An antispasmodic is a drug that helps suppress muscle cramps. As you know, such drugs are very often used to eliminate pain and other unpleasant sensations in the digestive system. It should also be said that the mentioned medications are often prescribed for diseases of the urinary system.
What antispasmodics do you know? The most popular remedy with such properties is the drug "Colofort". Instructions for use, price, reviews of doctors, analogues and features of this medication are listed below.
The composition of the drug, its packaging, release form and description
In what form is the preparation "Colofort" made? Reviews of doctors say that this tool can be purchased at any pharmacy in the form of lozenges.
The medication in question has a white color, a bevel, at risk, a flat-cylindrical shape.
What ingredients does Colofort contain? Reviews of doctors indicate that the active components of the drug in question are affinity-purified antibodies to:
- histamine;
- human TNF alpha;
- brain-specific protein S-100.
It should also be noted that, as additional components, this drug contains MCC, lactose monohydrate and magnesium stearate.
This medicine is sold in contour cells, which are packaged in cardboard packaging.
The main properties of the drug
What is remarkable drug "Colofort" (Koloforl)? Instructions, reviews (the price of the drug is indicated below) report that this medication has anti-inflammatory, anxiolytic and antispasmodic properties.
According to experts, the active components of this agent are able to modify the activity of the ligand-receptor interaction of endogenous regulators with the corresponding receptors (in particular, antibodies to S-100 proteins to serotonin and sigma-1 receptors, antibodies to TNF-alpha to TNF-receptors alpha, antibodies to histamine - to histamine H4 receptors, which are located in the digestive tract).
The combination of the listed active ingredients of the drug allows you to comprehensively affect the central as well as peripheral links of functional disorders of the intestinal tract, including abdominal pain.
Features of the drug
What is remarkable medicine "Colofort"? Reviews, instructions (the price of this medication is quite high) claim that the effectiveness of the drug in question is due to its components.
Antibodies to S-100 proteins have a broad psychotropic activity. They also have nootropic, anxiolytic, antidepressant and antiasthenic effects. This is manifested in the elimination of internal stress and anxiety. In addition, this component normalizes a number of visceral functions, including the work of the large intestine. It should also be noted that antibodies to S-100 proteins do not cause withdrawal syndrome (including addiction) and do not have a sedative effect.
Antibodies to histamine have decongestant, anti-inflammatory and antispasmodic effects.
Antibodies to TNF-alpha have a pronounced anti-inflammatory effect. In addition, they help normalize the balance of pro-inflammatory cytokines.
Operating principle
How does the drug "Colofort"? Reviews of doctors report that a combination of the listed components of the drug reduces visceral hypersensitivity of the receptors, and also normalizes the humoral and nervous regulation of the intestines.
It is impossible not to say that the drug in question eliminates bloating, helps to restore impaired gastrointestinal motility, reduces the severity of abdominal pain and eliminates the feeling of fullness of the stomach.
As for the antispasmodic effect of this medication, it manifests itself in a decrease in the tone of the walls of the gastrointestinal tract, normalization of the stool, relaxation of smooth muscles and a decrease in intraluminal pressure.
Indications for taking the drug
When should I take Colofort? Reviews of doctors claim that such lozenges work well in the treatment of IBS, that is, irritable bowel syndrome. It should also be said that this tool can be used for general functional disorders of the digestive system.
Contraindications
The medication in question has virtually no contraindications. It can not be taken only in the presence of hypersensitivity to its elements.
Dosing
Colofort absorbable tablets should be taken only inside, long before the meal.
A single dose of this medication is one or two tablets twice a day. The medicine must be kept in the mouth until completely dissolved.
The course of treatment with such a drug is from one to two months. In case of acute need, therapy can be extended up to six months or repeated after 60 days.
With an exacerbation of diseases of the digestive tract, the frequency of taking the medication in question should be increased up to four times a day for up to two weeks.
Unwanted effects
Does the medication in question cause negative reactions? What do consumer reviews say about this (about Colofort)? Analogues of the drug and the remedy itself are well tolerated by patients. Only sometimes, against the background of their intake, hypersensitivity reactions may develop.
Recommendations for taking the medicine
According to the instructions, the composition of the drug in question includes lactose. Therefore, it can not be prescribed to people with congenital galactosemia and lactase deficiency, as well as glucose or galactose malabsorption syndrome .
It should also be noted that this drug does not affect the patient's ability to drive dangerous machinery or vehicles.
Analogs and cost of medication
The cost of this drug is approximately 400-430 rubles per 100 absorbable tablets.
This remedy can be replaced with Pepsan-R, Antiflat Lannacher, Bobotik, Plantex, Bebinos, Disflatil, Gascon Drop, Gastrocap, Dietetel, Iberogast, Meteospazmil "," Sub Simplex ".
The drug "Colofort": reviews
Real reviews of doctors about this tool are positive. According to the statements of experienced specialists, the medication in question is effective in irritable bowel syndrome.
As a rule, after a course of treatment with this drug, patients fully normalize their stools. Also, all unpleasant sensations associated with the mentioned intestinal disease disappear in patients.