Pregnancy is an important stage in the life of every woman. To make it easy, you must follow all the doctor's recommendations. You should also pay special attention to your body during pregnancy planning. Only in this case, both the health of the mother and the condition of the unborn child will not require additional help from specialists.
general information
It is no secret to anyone that the process of preparing for bearing the fetus is as complex as the pregnancy itself. Before becoming parents, it is recommended to undergo a thorough examination of the body, and pay special attention to the state of the circulatory system. Indeed, it is thanks to her that the child receives nutrition from the mother, which affects its full development.
The drug "Curantil" when planning pregnancy is prescribed very often. This is due to the fact that such a drug is one of the few that can improve the blood flow of a future mother. In this case, it must be remembered that the intake of such a medication should be carried out exclusively as prescribed by the gynecologist. Self-administration of a drug with an incorrectly selected dosage can adversely affect a woman's health.
Description, form, composition
When planning pregnancy, Curantil is the most commonly prescribed drug. It is available in the form of tablets coated with a yellow or greenish-yellow shell, which are round in shape with a smooth and uniform surface.
The active substance of this medicine is dipyridamole. The preparation also includes auxiliary components in the form of corn starch, lactose monohydrate, magnesium stearate, talc, gelatin and silicon dioxide colloidal.
On sale, such a tool (100 tablets) comes in bottles of colorless glass, placed in cardboard boxes.
Basic properties
Why is Curantil prescribed for pregnancy planning? Experts say that such a drug is a vasodilator of myotropic action. It is able to improve microcirculation, as well as have a slowing effect on platelet aggregation.
The active component of this drug expands the arterioles that are in the coronary blood flow system, and when taking high doses, in other parts of the circulatory system. It should be noted that, unlike calcium antagonists and organic nitrates, the expansion of large vessels does not occur when using this medication.
The vasodilating effect of Curantil 25 is due to inhibition mechanisms such as inhibition of phosphodiesterase and inhibition of adenosine uptake.
Other features of the medication
Why is Curantil prescribed for pregnancy planning? Such a drug is not only an effective antiplatelet agent, but also a good immunomodulator. The ability to positively affect the immune system of a woman is due to the ability of the drug to provoke the synthesis of interferon.
Supporting the body's defenses at the stage of conception and during gestation is an integral part of preparation. It is during this period that a woman is most susceptible to attacks of viruses and infections. Moreover, when planning pregnancy, Curantil positively affects the growth of the endometrium, which is essential for the successful implantation of a fetal egg. It should be remembered that with insufficient thickness of the inner layer of the uterus, a woman may experience a biochemical pregnancy. In this case, taking medication is required. That is why "Curantil 25" when planning pregnancy is very often prescribed for poor blood circulation, as this can interfere with the full growth of the uterus.
Pharmacokinetic properties
After a single oral administration of a medicine in a dosage of 150 mg, the maximum concentration of dipyridamole in the blood is reached within 60 minutes.
The active substance of the agent under consideration binds almost completely to plasma proteins. In this case, dipyridamole accumulates in red blood cells and in the heart.
The active component in the liver is metabolized through communication with glucuronic acid. Its half-life is 20-30 minutes. The drug is excreted along with bile.
What is it prescribed for?
The drug "Curantil" when planning pregnancy is recommended for women in the presence of the following conditions:
- varicose uterus;
- insufficient growth of the endometrium;
- "Thick blood" or increased blood coagulation;
- in order to prepare for IVF.
Other indications for use
For what purposes can the drug “Curantil” be prescribed when planning pregnancy? Reviews of experts report that such a medication has many different indications. The main ones are the following:
- prevention of placental insufficiency, including with complicated pregnancy;
- prevention and treatment of cerebrovascular accidents;
- the presence of discirculatory encephalopathy;
- microcirculatory disorders (as part of combination therapy);
- intolerance to acetylsalicylic acid (as a replacement);
- treatment and prevention of venous and arterial thrombosis;
- prevention of thromboembolism;
- treatment and prevention of influenza and acute respiratory viral infections (as an immunomodulator).
Contraindications
An effective regimen of taking "Courantil" when planning pregnancy should be selected only by a specialist. In this case, the doctor must necessarily take into account the presence of the following contraindications for use in the drug:
- acute myocardial infarction;
- subaortic aortic stenosis;
- chronic obstructive pulmonary disease;
- coronary artery atherosclerosis (common stenotic);
- collapse;
- heart failure (during decompensation);
- arterial hypotension;
- hemorrhagic diathesis;
- unstable angina pectoris;
- liver failure;
- severe arterial hypertension;
- heart rhythm disturbances;
- diseases with a high risk of bleeding;
- chronic renal failure;
- high sensitivity to drug substances.
How to take Curantil when planning a pregnancy?
If there are blood problems, experts recommend taking Curantil for three months before trying to conceive. At the same time, the decision to use this drug should not be independent, since it can adversely affect the patient's condition, which will delay the time of pregnancy for another indefinite time.
Also, before taking the medication in question, you must pass all the necessary tests and undergo an ultrasound of the pelvic organs.
The maximum dosage of Curantil when planning pregnancy is 600 mg. However, it is used only in the presence of serious pathologies.
In general, there are several regimens for taking this medicine:
- In order to strengthen the immune system, the patient is recommended to take 50 mg of the drug per day for a month. Together with treatment, it is necessary to monitor the immune system, as well as donate blood for coagulation.
- When planning pregnancy, this drug is prescribed at a dose of 75 mg three times a day. The medication must be taken with a course of 21 days, and then take a break for the same period.
How to drink Curantil when planning pregnancy? This remedy should be taken before meals or after 1.5–2 hours after eating. The tablet is forbidden to chew. It must be washed down with plain clean water (not tea, not soda).
Side effects
In some cases, the drug "Curantil" can cause the following adverse reactions:
- palpitations, thrombocytopenia, tachycardia (including with the simultaneous use of other vasodilators), nausea, bradycardia, urticaria;
- vomiting, flushing, epigastric pain, flushing of the face, skin rash, coronary stealing syndrome, diarrhea, decreased blood pressure;
- dizziness, bleeding, noise in the head, weakness;
- increased bleeding after surgery, arthritis, headache, myalgia, sensation of stuffy ear, rhinitis.
When taking the drug in therapeutic dosages, side effects may be mild and may be transient.
Interaction with other drugs
When taking Curantil, it is undesirable to conduct parallel treatment using other anticoagulants and acetylsalicylic acid. Otherwise, there is a high risk of developing adverse reactions.
It's important to know!
While taking "Courantil" should not eat foods and use drugs that contain theophylline or caffeine. This combination of substances can significantly reduce the effectiveness of the drug. The same applies to the simultaneous use of coffee or tea with the drug (due to the content of xanthine derivatives in them). With such combinations, the vasodilating effect of Curantyl may decrease.
It should also be remembered that the medication in question is prohibited for children under 12 years of age (due to the lack of clinical experience with its use at a young age).
During treatment with Curantil, special care should be taken when driving vehicles or using other complex mechanisms, as a result of a drop in blood pressure (while taking the medicine), the patient may be affected by the speed of psychomotor reactions, as well as impaired concentration.
Reviews of patients about the drug
What do women planning pregnancy and also those who are already bearing a child say about Curantil 25? Patient reviews about this medicine are mostly positive. Firstly, it improves blood flow, which contributes to the successful conception and subsequent attachment of the embryo to the uterus. Secondly, "Curantil 25" prevents the occurrence of thrombosis, which allows you to safely endure the child. Thirdly, the drug improves the immune system, minimizing the risk of acute respiratory viral infections and acute respiratory infections in a pregnant woman.
Also, patients note that side effects after taking such a drug are extremely rare (nausea, dizziness, vomiting are sometimes observed).
Of the negative reviews regarding the drug "Curantil 25" can be noted those that mention its overpriced (for 100 tablets you need to give about 600 rubles).