At what dose is Bronchobos (syrup) prescribed? Instructions for the use of mucolytic drugs are described in detail below. Also in the materials of this article you can find information about the purposes for which the medication is used, how much it costs, whether it has adverse reactions, analogues and contraindications.
Composition and packaging
In what packaging does Bronchobos (syrup) go on sale? Instructions for use of the mucolytic agent are enclosed in a pack of cardboard, where there is a measuring spoon of polystyrene with tags, as well as a bottle of dark brown glass with an aluminum cap having a sealant, a protective mechanism and a first opening control.
The active substance of this medication is carbocysteine. Also, its composition includes auxiliary compounds in the form of ethanol, glycerol, sodium hydroxide, citric acid monohydrate, sodium carmellose, methyl parahydroxybenzoate, propyl parahydroxybenzoate, sodium saccharinate, azorubine, raspberry flavoring and purified water.
Syrup "Bronchobos", reviews of which are described below, is a 2.5% or 5% transparent preparation with a slightly viscous consistency, raspberry aroma and bright red color.
Pharmacodynamics of the drug
Mucolytic drugs, including Bronchobos syrup, have an expectorant effect. This effect of the drug is due to the activation of the enzyme - sialic transferase, which is produced in goblet cells in the bronchial mucosa.
The drug normalizes the numerical ratio of acidic as well as neutral sialomucins in bronchial secretions. In addition, it restores the viscosity of the mucus and its elasticity.
What other features do mucolytic drugs have? They contribute to the regeneration of the mucous membranes, normalize the structure, and also activate the ciliated epithelium. Syrup "Bronchobos" restores the secretion of immunoglobulin A as a specific defense, as well as the number of sulfhydryl groups in the mucus and its components as a non-specific defense. Also, this drug improves mucociliary clearance.
Pharmacokinetic parameters of the drug
The drug "Bronchobos", the price of which will be indicated below, is absorbed quickly and completely. Moreover, it has a rather low bioavailability (less than 10% of the dose taken). The highest level of active carbocysteine in the mucous membranes and blood is reached after 1.5–2 hours. Its therapeutic level persists for 8 hours. The drug lingers for the longest time in the liver, blood flow, and middle ear. At maximum concentrations, it accumulates in the secretion of the bronchi (about 17.5% of the dose taken).
The drug is metabolized in the liver. It is characterized by the effect of the first passage. About 60–90% of the drug is excreted through the kidneys in an unchanged form.
The half-life of the drug is 2-3 hours. Its complete elimination occurs after three days.
Indications for use of syrup
For what purposes is Bronchobos prescribed for children and adults? According to the instructions, such a syrup effectively helps with:
- inflammatory processes in the sinuses and middle ear, including sinusitis, rhinitis and otitis media;
- chronic and acute bronchopulmonary diseases accompanied by impaired elimination of mucus and its secretion (for example, with bronchitis, tracheitis, bronchial asthma, tracheobronchitis and bronchiectasis).
In addition to the above, the medication in question is actively used during the preparation of the patient for bronchography or bronchoscopy.
Contraindications
Under what conditions is it not recommended to take Bronchobos (syrup)? Instructions for use indicate the following contraindications for all dosage forms:
- ulcer of the duodenum and stomach (especially with exacerbation);
- hypersensitivity to the components of the drug;
- cystitis and chronic glomerulonephritis (including with exacerbation);
- age up to 15 years.
For 2.5% and 5% syrup:
- epilepsy;
- various liver diseases, alcoholism;
- brain diseases and injuries of this organ;
- breastfeeding and pregnancy.
For 2.5% syrup:
Conditions for careful use of the drug:
- history of duodenal ulcer and stomach ulcer.
Preparation: Bronchobos (syrup): instructions for use
According to the attached instructions, this medication must be taken orally. The dosage of the drug should be determined using a measuring spoon.
For adults, the drug is prescribed in an amount of 15 ml, which is equal to 3 scoops of 5 percent syrup (three times a day).
For children aged 3–6 years, a 2.5 percent medication is given 5 ml 2–4 times a day, that is, in the amount of 1 scoop at a time.
Children from 6 years of age are prescribed 5-10 ml of 2.5 percent syrup three times a day, that is, 1-2 measured spoons.
Drug overdose
When taking high doses of syrup, the patient may experience stomach pain, diarrhea, and nausea. To eliminate such deviations, symptomatic treatment is prescribed.
Side effects
Taking the Bronchobos medication can cause unwanted effects from the following organs and systems:
- Gastrointestinal tract: epigastric pain, nausea, bleeding, vomiting, diarrhea.
- Immune system: allergic reactions in the form of exanthema, urticaria, skin itching, angioedema.
- Other: dizziness, onset of weakness, malaise.
- People with bronchial asthma and elderly patients may experience airway obstruction.
Drug interaction
When taking any dosage forms of the drug:
- The bronchodilator effect of the drug "Theophylline" increases.
- In the treatment of infectious and inflammatory processes in the lower and upper respiratory tract, a mutual increase in glucocorticoid effectiveness can be observed, as well as a separate antibacterial effect.
- With atropine-like drugs, the antitussive effect is weakened.
When taking syrup:
- With extreme caution (due to the presence of ethanol) used with drugs that cause fever, vomiting, redness and tachycardia.
- With extreme caution (due to the presence of ethanol), they are taken with drugs such as Cefamandol, Disulfiram, Cefoperazone, Latamoxef, Chloramphenicol, Glipizide, Glibenclamide, Chlorpropamide, Tolbutamide ”,“ Griseofulvin ”,“ Metronidazole ”,“ Tinidazole ”,“ Secnidazole ”,“ Ornidazole ”,“ Procarbazine ”,“ Ketoconazole ”.
Special recommendations
Syrup "Bronchobos" contains ethanol. In this regard, it is prescribed with caution to children and people suffering from alcoholism. After taking the drug in patients, there is a violation of attention and speed of psychomotor reactions. In this regard, the use of this medication is not recommended for drivers of vehicles and those who work with complex mechanisms.
Terms of sale, storage and shelf life
Such a drug is sold in pharmacies without a doctor’s prescription. It should be stored out of the reach of children, observing a temperature regime of 16-30 degrees. The shelf life of the syrup is three years (without violating the integrity of the package).
The drug "Bronchobos": analogues and cost
Currently, there are many analogues of this tool. The closest to the mechanism of action is the drug "Fluifort" (syrup). He is also a good mucolytic. In addition, the medication presented can be replaced by such means as Fluditek, Bronkatar, Libexin Muko, Mukopront and Mukosol.
How much does the Bronchobos cost? The price of this medicine depends on its form of release. 5% syrup can be purchased for 550-570 rubles, and 2.5% of the drug - for 420 rubles.
Drug Reviews
Like Fluifort, Bronchobos Syrup is a high-quality and effective mucolytic. This is the opinion most patients who used this medication to treat chronic and acute bronchopulmonary diseases.
According to experienced experts, this drug is able to quickly and efficiently liquefy, as well as remove sputum from the bronchi. Another advantage of this tool is that it can be given to young children from two years of age, as evidenced by many reviews. This is due to the fact that the syrup in question has practically no side effects and contraindications.
As for the negative reviews, most often they are associated with the price of the mucolytic drug. However, pharmacists argue that the cost of this tool is fully justified, since it is one of the most effective drugs against bronchopulmonary diseases.