“Flemoklav Solutab” is an antibacterial agent from the group of penicillins with a wide spectrum of exposure with a beta-lactamase inhibitor. The drug can be used only after visiting a doctor and taking tests. Self-medication without examination can ruin the clinical picture of the disease and make it difficult to determine the correct diagnosis.
Structure
Release form "Flemoklava 500" - tablets for oral administration, packaged in blisters. One capsule contains the following active ingredients:
- amoxicillin;
- clavulanic acid.
Depending on the concentration of the main trace elements in the medication, capsules with a dosage of 125, 250, 500 and 1000 milligrams are produced.
Flemoklav 500 contains additional components, for example:
- povidone;
- cellulose;
- a salt of magnesium and stearic acid;
- flavoring;
- sodium saccharin;
- dispersed cellulose.
Indications
Flemoklav 500 is recommended for use in diseases caused by bacteria that are sensitive to penicillin and clavulanic acid:
- Sinusitis (an inflammatory process in the mucous cavity of one or more sinuses of the nose).
- Sinusitis (inflammation of the maxillary sinuses).
- Inflammatory lesion of the mucous cavity of the frontal sinus, which is part of the anterior base of the skull.
- Tonsillitis (prolonged inflammation of the pharyngeal and palatine tonsils).
- Angina (an infectious lesion with local manifestations in the form of an acute inflammatory process of substances of the lymphatic pharyngeal ring, in most cases of tonsils, which is caused by streptococci or staphylococci, sometimes other bacteria, viruses).
- The inflammatory process in the mucous cavity and lymphoid tissue of the pharynx.
- Bronchitis (a diffuse inflammatory disease of the bronchi affecting the mucous membrane or the entire thickness of the wall of the bronchi).
- The inflammatory process in the trachea, in most cases of an infectious origin.
- Bronchopneumonia (acute infectious pulmonary disease involving all structural elements and mandatory damage to the alveoli).
- An infectious inflammatory disease in which not only the bones and bone marrow are affected, but also the whole organism.
- Adnexitis (female gynecological disease affecting the fallopian tubes).
- Infectious inflammatory process in the fallopian tubes.
- Cervicitis (inflammation of the lower segment of the uterus, which includes the inflammatory process of the mucous cavity of the vaginal part and the mucous membrane of the uterine canal).
- Necrotic damage to the surface of the skin, which develops as a result of the penetration of pyogenic bacteria into it.
- A large group of skin infectious diseases that are provoked by various strains of streptococcus.
- Boils (purulent inflammation of the hair bulb, sebaceous gland and connective tissue, which is caused by negative microorganisms, mainly staphylococcus).
- Carbuncle (acute inflammation of several adjacent hair follicles with the formation of an extensive focus of necrosis in the skin).
- Erysipelas (a common infectious-allergic disease of the skin and subcutaneous tissue, prone to relapse).
- Urethritis (a disease associated with the development of an inflammatory process in the wall of the urethra).
- The inflammatory process in the kidneys, which occurs in acute or chronic form, the disease is quite common and dangerous to health.
- Inflammation of the urea, mainly of an infectious nature.
- Interstitial nephritis (a pathology that occurs in the kidneys).
Contraindications
Flemoklav 500 has the following prohibitions on use:
- Severe liver damage, accompanied by a violation of its functioning.
- Acute viral disease, which is characterized by febrile conditions, disturbance of the pharynx, and also inflammation of the lymph nodes.
- Kidney inflammation.
- Acute renal failure.
- Minor age.
- Individual intolerance to the components of the drug.
- Severe adverse reactions to antimicrobials.
- Pregnancy (first trimester).
With special care, the drug is recommended for women in an “interesting position”, nursing mothers, people who have diseases of the gastrointestinal tract.
Instructions for use
The dosage of the drug and the duration of therapy are selected by the attending doctor. It all depends on the testimony, age, weight and characteristics of the patient.
According to the instructions, adult patients and adolescents over twelve years of age (whose weight is more than forty kilograms) are prescribed 1000 milligrams of the active substance per day, dividing the dose into two doses in the dosage of Flemoklav Solutab 500 mg.
Children from six to twelve years old are prescribed 250 milligrams of the drug three times a day, that is, 750 milligrams.
Babies from one year to six years (depending on weight) are prescribed 125 or 250 milligrams of the drug three times a day under the supervision of a doctor.
Children "Flemoklav 500" is initially dissolved in one teaspoon of water so that there are no lumps, washed down with water. In order for the effectiveness of the antibacterial agent to be increased, the medication must be taken at the same time, preferably after a meal.
The duration of the course (“Flemoklav Solutab”), as a rule, is five days, but in rare situations the therapy is extended to ten days under the supervision of a doctor.
Use during pregnancy and lactation
In the first three months of pregnancy, taking Flemoklav Solyutab is prohibited, since at this stage all the organs and systems of the unborn baby begin to form and lay in, and the effect of the drugs on the mother's body can lead to disruptions of this important process.
The use of the medication in the following months of pregnancy is allowed, but strictly according to the indications. Before using Flemoklav 500 tablets during pregnancy, the doctor carefully weighs the risk-benefit ratio for the expectant mother and baby. Treatment is carried out in a minimally effective dosage under the supervision of a physician.
According to the instructions for use "Flemoklava 500" it is known that during lactation the drug is allowed to take. The main micronutrients that make up the drug are excreted in milk; during the studies, no negative effect of the drug on the baby's body was found.
Adverse reactions
During the administration of Flemoklav Solutab tablets, certain side effects may develop in patients with increased sensitivity to the medication:
- Thrombocytosis (a hematological pathology characterized by an increase in blood platelet count).
- Leukopenia (a decrease in white blood cells in human plasma).
- Anemia (decreased blood count of red blood cells).
- Thrombocytopenia (a condition characterized by a decrease in platelet count below the standard).
- A pathology in which there is a decrease in the level of leukocytes due to monocytes.
- Pain in the stomach.
- An unpleasant burning sensation in the area behind the sternum and in the upper abdomen.
- Vomiting.
- Diarrhea (rapid, multiple loose stools).
- Digestive disorders, which is caused by an infectious or non-infectious lesion of the intestine.
- Pseudomembranous colitis (acute inflammation of the large intestine that occurs with antibiotics).
- Intestinal dysbiosis (quantitative and qualitative violation of the normal intestinal flora).
- Liver disease.
- Cramps (involuntary convulsive contraction of a muscle or muscle group, usually accompanied by sharp and aching pain).
- Violation of sensitivity, which is characterized by abruptly appearing Disease, which is characterized by motor anxiety of varying severity, often accompanied by speech arousal.
- Insomnia (a pathological condition in which the process of the onset and maintenance of sleep is disturbed).
- Aggression (behavior that is aimed at causing physical or psychological harm, up to the liquidation of the object).
- Inflammation of the mucous membrane of the urea.
- An infectious disease that is relatively easy to treat, but if not properly diagnosed and treated, can lead to coma and even death.
- Irritation and itching in the female genital area.
- Rashes on the skin.
- Exanthema (instant infectious condition in children of preschool age, which is caused by strains of herpes of the sixth and seventh type).
- Urticaria (skin disease, dermatitis of mainly allergic origin, characterized by the rapid onset of severely itchy blisters).
- Inflammatory disturbance of the skin, which occurs as a result of the influence of destructive factors of a chemical, physical or biological nature.
- Drug fever (a condition that occurs simultaneously with taking antibiotics and disappears after they are canceled, but this is if there is no other reason).
- Anaphylaxis (allergic manifestations of an immediate type, a state of instantly increased body sensitivity).
- Serum sickness (an allergic disease caused by the administration of heterologous or homologous serums or drugs).
- The development of superinfection (the process by which a cell initially infected with one virus is codified after some time by another strain of the virus or another virus).
According to the instructions for use for Flemoklav 500, in case of side effects it is necessary to consult a doctor for help.
In case of an overdose, gastric lavage is necessary, and activated carbon is also required. If kidney diseases occur, the patient undergo hemodialysis.
With a strong increase in the standard dosage of Flemoklav 500 mg or prolonged uncontrolled use, the patient has symptoms of overdose, manifested by an increase in side effects, impaired extracellular hyperhydration, constant vomiting and diarrhea.
Interaction with other drugs
When taking the drug with acetylsalicylic acid or Indomethacin, the duration of Amoxicillin in the blood and bile increases, which increases the likelihood of side effects.
According to the instructions for use with Flemoclav 500, when using the drug with laxatives or aminoglycosides, the process of assimilation of Amoxicillin in the body decreases, after which the therapeutic effect of the antibacterial agent will be small.
With the combined use of Flemoklav with Allopurinol, the likelihood of skin rashes increases. When taking Flemoklav Solyutaba with indirect anticoagulants, the patient has an increased risk of bleeding.
In rare situations, under the influence of the drug, the effectiveness of oral contraceptives decreases, therefore, representatives of the beautiful half of humanity who prefer this type of protection against unwanted pregnancy need to be careful and use condoms or other barrier agents during treatment.
Features
Before using Flemoklava Solutab, patients who are prone to allergic reactions to drugs should definitely be tested for sensitivity, since penicillins quite often cause serious problems. When symptoms of anaphylaxis or angioedema appear, it is forbidden to use the medicine.
You can not use Flemoklav Solutab (500 milligrams) longer than the standard period (no more than fourteen days), since in this situation the likelihood of superinfection and exacerbation of all signs of the disease increases. In the absence of the effect of the medication within five days after the start of therapy, the patient urgently needs to consult a doctor to clarify the diagnosis and adjust the prescribed course.
With the development of diarrhea due to the use of pills and severe pain in the abdomen, it is important to stop therapy immediately and contact a medical professional, possibly pseudomembranous colitis.
According to the instructions for use, Flemoklav 500 should be taken with caution to people with chronic liver diseases, since under the influence of an antibacterial drug, the general condition and functioning of the organ may decrease.
It is not recommended to independently interrupt the course of drug therapy immediately as soon as the first improvements in the general condition have appeared. It is necessary to undergo the treatment prescribed by the doctor to the end. Termination of the course ahead of schedule may cause the emergence of bacteria resistance to Amoxicillin and the transition of the disease to the chronic stage.
According to reviews of Flemoklav 500, during treatment with medication, care must be taken when driving a car and working with equipment that requires a quick reaction. This is due to the fact that during therapy the patient may experience sudden dizziness.
Substitutes
The following medicines are analogues of Flemoklav 500:
- "Augmentin."
- Amoxiclav.
- Amoxicillin.
- "Medoklav".
- "Arlet."
- "Ecoclave".
- Amoklavin.
- "Clavocin."
- Moksiklav.
- Cefixim.
- "Cefuroxime."
Amoxiclav
The drug belongs to antibiotics with a wide spectrum of effects. It is active against most microorganisms that cause infectious diseases. The drug is considered to be a representative of the therapeutic group of semisynthetic antibacterial agents of the penicillin series.
The medication is made in the form of tablets of fourteen pieces per pack. Active trace elements of the drug are amoxicillin and clavulanic acid.
The number of capsules in the package is designed for an average course of therapy. Different dosage of Amoxiclav helps to regulate the receipt of an antibacterial agent during its use.
The duration of the course and the dosage of the drug is determined by the attending doctor on the basis of various information: improvement of the general condition, course of the infection process, its source. And it is also necessary to conduct a laboratory study of the effectiveness of treatment. The cost of Amoxiclav varies from 100 to 800 rubles.
Augmentin
A complex drug from the group of antibacterial drugs with a wide spectrum of action, which contains amoxicillin and clavulanic acid. The medication is available in the form of tablets for oral administration.
Augmentin capsules are active against gram-positive and gram-negative pathogenic bacteria, as well as the active microelements of the drug adversely affect some other sources of serious diseases.
Tablets are a pharmacological medication of prolonged action, which mainly distinguishes them from other drugs, which are based on amoxicillin. The drug can be used to eliminate the source of pneumonia, which is resistant to penicillins.
The duration of the course and the dosage of Augmentin are determined by the doctor for each individual patient individually. It must be remembered that the drug is an antibiotic, so you can not start to use it without permission and when you want. In addition, some diseases are triggered by bacteria that are not susceptible to the effects of active micronutrient tablets.
The dosage of the medication is set by the doctor depending on many factors:
- age
- the diagnosis;
- complications;
- kidney and liver work;
- weight.
To achieve maximum absorption of substances and reduce the likelihood of side effects, tablets are recommended to be used before meals. The cost of the drug is from one hundred twenty to three hundred and seventy rubles.
Amoxicillin
The medicine is available in the form of coated tablets, intended for oral administration. Amoxicillin (a structural analogue of Flemoklava Solutab) belongs to the group of antibacterial drugs with a wide spectrum of influence.
The antibacterial agent is not destroyed by the action of gastric juice and is completely absorbed from the digestive system. The maximum content in the blood is reached after one to two hours. With increasing dosage, its concentration also doubles. Total absorption is not dependent on the presence of food in the stomach.
The bioavailability of an active trace element with blood proteins is twenty percent. The drug is evenly distributed throughout all tissues and systems of the body. It instantly penetrates into the lung tissue, as well as middle ear fluid, urine and bile. In elevated concentrations, stored in the liver.
The half-life is an hour and a half. With kidney disease, this period takes up to twenty hours. About sixty percent of Amoxicillin is excreted by the kidneys, a small part - with feces. In the inflammatory process of the meninges, the drug in small volumes can pass through the blood-brain protection, is eliminated during hemodialysis. The cost of Amoxicillin varies from 50 to 100 rubles.
Storage conditions
The drug is dispensed from pharmacies according to the doctor’s prescription. Store the medicine in a cool, dry place, inaccessible to children. The shelf life of Flemoklav 500 is three years.
The price of the drug varies from 300 to 500 rubles (depending on dosage) for example:
- Flemoklav Solyutab 125 milligrams - 350 rubles.
- Tablets 250 milligrams - 450 rubles.
- Capsules 500 milligrams - 500 rubles.
In their reviews of Flemoklava Solutab, patients noted the following advantages of the drug: excellent bioavailability of the drug, rapid achievement of the effect, and the possibility of children taking it.