The Meronem medication (the instructions for use contain this information) is active in relation to most gram-positive, gram-negative aerobes and anaerobes. The medicine is effective both in combination with other drugs, and as a mono-drug. A medicine is produced in the form of a powder for the manufacture of a solution for injection.
Appointment
Meronem (reviews by doctors confirm this) can be used in patients from three months of age. The drug is indicated for infectious inflammatory lesions caused by the activity of microbial strains that are sensitive to the drug. In particular, it is prescribed for infections in the urinary tract, abdominal cavity, pelvic organs (endometritis, for example). The indications include pneumonia (including low-mine), septicemia, meningitis.
Antibiotic Meronem. Contraindications
The drug is not recommended for severe intolerance to the components of the drug, anaphylactic and severe skin reactions during therapy with any drug with a beta-lactam structure (to cephalosporins and penicillins). The Meronem medication is not prescribed (the instructions for use confirm this) for patients under the age of three months. Caution is observed with complex use with nephrotoxic drugs, with disorders of the gastrointestinal tract (in the presence of colitis in particular). The medication is contraindicated during gestation and breastfeeding. If treatment is necessary during lactation, feeding should be discontinued.
The drug "Meronem." Instructions for use. Side effects
As practice shows, the drug as a whole is tolerated satisfactorily by patients of different ages. Adverse events rarely occurred requiring discontinuation of treatment. Hemolytic anemia, headache, thrombocytosis, increased irritability, eosinophilia, anxiety may occur due to therapy. Some patients have insomnia, depression, neutropenia, vomiting, thrombocytopenia, agranulocytosis, convulsions (rarely). Instructions for use include pseudomembranous colitis, increased activity of liver transaminases, urticaria, constipation, paresthesia, and drowsiness to the undesirable consequences of therapy with the Meronem drug. Some patients develop anaphylaxis, necrolysis (toxic epidermal), erythema multiforme type, insufficiency of cardiac function, change in pressure (decrease or increase). Rarely, dyspnea, an increase in creatinine and urea, pulmonary thromboembolism, tachycardia, cardiac arrest, bradycardia may occur. As local reactions, soreness at the injection site, candidiasis of the oral mucosa and vagina may appear.
Dosage regimen
Means "Meronem" instructions for use recommends appointing in accordance with the tolerance of the patient, the nature of the course and the type of pathology personally. The initial amount of the drug is 0.5 g for adults. Dosages for infants are calculated by weight. The recommended amount is 30-60 mg / kg / day. The total dosage is distributed over several administrations.