The preparatory stage for the diagnostic examination of the intestine is a very important thing, because the correct diagnosis and further treatment of the disease depend on it. The main thing here is to cleanse the intestines well. There are many drugs for this purpose, but Moviprep is considered the best. Reviews note that its use helped to prepare the procedure qualitatively and to establish the exact cause of the disease.
Composition and form of release
Available in the form of a powder enclosed in a sachet-packet drug "Moviprep". The composition in package “A” and “B” is different.
The powder in package "A" has a characteristic smell of lemon and a white-yellow tint. It contains the following components: macrogol 3350, sodium sulfate, sodium chloride, potassium chloride. Auxiliary components are potassium acesulfame, aspartame and lemon flavor.
The powder for the preparation of solution "B" practically does not smell. It has a light brown color. Contains ascorbic acid mixed with sodium ascorbate.
Sachets are made of polyethylene and packaged in a cardboard box along with instructions for use. The package contains two packages “A” and the same number of sachets “B”.
The drug "Moviprep" is made in the UK. Manufacturer - Norgin Limited. The drug should be stored in a dry place, protected from light and children. At a temperature not exceeding + 25 ° C.
The shelf life of the drug in powder is three years. Shelf life of the reconstituted solution is 24 hours, provided that it will be stored at a temperature of no more than 8 ° C.
pharmachologic effect
The drug "Moviprep" (reviews, by the way, note the high cost of the medication) refers to laxatives with an osmotic effect.
The use of an electrolyte solution inside, the main part of which consists of a macrogol, provokes moderate diarrhea. This action of the drug contributes to the rapid cleansing of the colon from its contents.
Macrogol 3350 together with sodium sulfate and vitamin C (ascorbic acid) give an osmotic effect, which helps to weaken the intestines and its rapid emptying.
The substance macrogol 3350, as part of the drug, increases the volume of feces, which leads to more severe intestinal motility.
The electrolytes contained in the preparation and the liquid that it is recommended to drink at the same time as Moviprep prevent the medicine from disturbing the water-electrolyte balance in the body.
Macrogol 3350 practically does not change when passing through the intestinal environment and is not absorbed from the gastrointestinal apparatus. The volume of the drug that managed to be absorbed leaves through the kidneys, with urine.
Most of the ascorbic acid is absorbed in the small intestine. There is an inverse relationship, oscillating between the absorbed share of the drug and the dosage taken.
When using a solution prepared from powder, inside in an amount of 30-180 mg, absorption accounts for 70-85%. If vitamin C will continue to be consumed in a dose of up to 12 g, then its absorption will become 2 g. Ascorbic acid, used in large doses, comes out unchanged through the kidney organ.
Indications for use of medicine
Indications for the use of the drug are various diagnostic studies, before which it is necessary to cleanse the intestines well. So, they take Moviprep before colon colonoscopy, X-ray examination, and before other clinical measures that are aimed at studying the intestinal environment. A medication is prescribed before surgery in the intestine.
When can not I use a medication?
Despite the effective action of the drug, not everyone can resort to the Moviprep medicine. Contraindications to the use of this tool are: the presence of excessive sensitivity to the active substances of the drug, as well as gastroparesis and bowel obstruction. A ban on the use of this medication is intestinal perforation and the possible likelihood of it.
Aspartame is a part of the medicine, therefore Moviprep should not be taken by people with phenylketonuria. Do not prescribe medication with a lack of glucose-6-phosphate dehydrogenase, severe pathologies of the intestinal organs and with toxic megacolon, which appeared due to inflammation in the intestinal environment.
Contraindication to use is Crohn's disease, colitis and an ulcer. Do not use the drug in an unconscious state and in children whose age has not reached eighteen years.
With extreme caution, the drug is prescribed for a failure of the vomiting reflex, a predisposition to regurgitation and aspiration. Particularly careful when taking the medication should be persons suffering from heart and kidney failure, which are in a difficult stage of development.
The drug "Moviprep": instructions for use
The drug is taken orally. The solution prepared from the powder (2 liters) can be taken at a time. That is, two liters of the prepared medicine should be drunk on the eve or on the day of the upcoming procedure. The finished substance can be divided into two methods. One liter can be drunk in the evening, the day before the upcoming procedure, and the second on the day of the upcoming event.
If there is a surgery on the intestine, then two liters of the resulting solution should be taken the day before.
The prepared solution retains its properties for 24 hours. In addition to the solution, you should drink a liter of any liquid. This can be ordinary still water, fruit juice without adding pulp, various drinks not containing alcohol, and the same tea and coffee without adding milk.
With any method of taking the solution, the use of liquids, including the Moviprep drug (the instructions for use before which should be carefully studied), must be stopped one hour before the start of the diagnostic procedure.
If the solution is taken once, in the amount of two liters in the morning, then its reception must be stopped two hours before the intended event, and drinking other liquids in an hour. At the very beginning of the use of the Moviprep preparation, the use of solid food should be excluded until the end of the clinical procedure.
How to breed "Moviprep"? To prepare one liter of laxative solution, the powder from package “A” should be mixed with a sachet marked “B” in a small volume of water. Bring the resulting amount of solution with water to a liter. The second liter of solution is prepared similarly from the remaining sachets "A" and "B".
The total amount of solution obtained from one Moviprep package is equal to two liters.
Negative body reactions
The drug "Moviprep" causes diarrhea during bowel preparation. Since the medicine acts in a special way, at the preparatory stage negative symptoms occur in almost all patients. The most common are: bloating, nausea, vomiting, pain in the abdomen. There is also irritation and discomfort in the anus. In some cases, sleep disturbance, dehydration was observed.
Along with taking the medication, an allergic reaction can develop, which manifests itself in the form of rashes on the skin, urticaria, dyspnea, itching, as well as anaphylactic shock and Quincke's edema.
When using the solution, dizziness, pain in the head, cramps in the limbs can be observed. In some cases, patients are concerned about dehydration, electrolyte abnormalities may occur, including a decrease in carbonate and changes in plasma chlorides. People, when using the solution, may be disturbed by a short increase in blood pressure, arrhythmia, heart palpitations, flatulence. Sometimes there are deviations from the indicator of liver tests.
The drug can cause general malaise, fever, hunger, chills, thirst and other discomfort.
special instructions
Elderly people, as well as people weakened and emaciated, should take the drug under the supervision of a doctor. This applies to people prone to regurgitation or aspiration, accompanied by impaired consciousness. To avoid dehydration, you should drink plenty of fluids, in addition to the Moviprep medication.
When does the drug begin to act? Almost immediately after its application, the active process of cleansing the body begins.
If people are weakened, and they have many concomitant pathologies, such as impaired renal organ function, arrhythmia, as well as a malfunction in the balance of electrolytes, then an analysis should be done to determine the number of electrolytes before treatment and after the clinical procedure. You also need to monitor the functioning of the kidneys and make an ECG.
Rarely enough, patients experience a severe form of arrhythmia, including with atrial fibrillation, which is associated with the use of laxative drugs with an osmotic effect for the intestinal preparation procedure. A similar picture is observed in patients with cardiological risks and a violation of the number of electrolytes.
If arrhythmia appeared during the use of Moviprep, there are symptoms that indicate a violation of the water-electrolyte balance, then you need to immediately determine the number of electrolytes in the blood, make an ECG and perform adequate therapy for the revealed abnormalities.
If flatulence, abdominal pain, bloating and other symptoms occur, you need to stop taking the medicine and get medical advice.
A person who follows a sodium diet should take into account that the medicine has 56.2 mmol of absorbed sodium. The same applies to people on a diet with potassium control, because the composition of the medication includes 14.2 mmol of potassium per liter of solution.
During treatment with Movipred it is not permitted to drive vehicles.
Drug Interactions
The laxative effect that the drug "Movipred" gives violates the absorption of other drugs that are used simultaneously with it. All oral medications should be taken one hour before using Movipred.
Overdose
The use of the drug in high doses can lead to an overdose. As a result, the water-electrolyte balance is disturbed.
To eliminate this ailment, it is enough to consume enough water and fruit juices. If necessary, infusion solutions can be injected into a vein.
Drug cost
The drug "Moviprep" is sold in every pharmacy in the Russian Federation. Its cost ranges from 600 to 700 rubles. He is released only on prescription.
Analogs
If this drug seems expensive or it does not work for other reasons, then you can choose analogues instead of the drug "Moviprep". The most common include:
- Osmogol.
- "Lavacol."
- "Realaxan."
- "Polyoxyfumarine."
- Forlax.
- "Transipeg".
- Forteza Rompharm.
- Fortrans.
- Endofalk.
All of the above drugs contain macrogol and act in a similar way.
Patient Reviews
The drug "Moviprep" reviews has only positive. Doctors recommend this drug to be used not only in preparing the intestines for clinical diagnosis, but also in case of constipation, if other treatment was ineffective.
Patients note the lemon smell of the solution and the sweet-sour taste of the medicine. They say that the medicine works almost immediately, after a few minutes after taking it. Gently and quickly cleanses the intestines. Well tolerated by humans. The drug does not irritate the mucous membrane and does not damage it, but acts only on peristalsis. Patients recall that while taking this drug it is very important to drink plenty of fluids, at least one liter. Many consider it to be the best among other similar means.
Among the negative aspects of the medicine, people indicate its high cost and the taste of the solution that is too sweet and unpleasant.
From the foregoing, it can be concluded that Moviprep patient reviews are considered the most effective laxative medicine. They say that he perfectly prepares the body for colonoscopy and other diagnostic procedures for examining the intestines.