How to use and how much does the medicine “Febrofid” (gel) cost? Instructions for use, the price of the mentioned drug will be presented later.
From this article you will learn about which components are part of the drug, according to what indications it is prescribed, how it affects a person and whether he has analogues.
Description, composition and packaging
What is an external agent like Febrofid (gel)? Instructions for use, patient reviews report that it is a 2.5% colorless, slightly opalescent or transparent drug (may have a light yellow tint), which includes the lysine salt of ketoprofen.
Also, the medicament under consideration includes additional components in the form of polyethylene glycol, propyl hydroxybenzoate, triethanolamine, methyl hydroxybenzoate, carbomer and purified water.
Pharmacodynamics of an external agent
What pharmacological characteristics are inherent in the medicine "Febrofid"? The gel, the instructions for use of which is enclosed in a package of cardboard, is a local remedy that belongs to the NSAID group.
This drug has a pronounced anti-inflammatory, antiexudative and analgesic effect. The field of application of this medicine is painful sections of the musculoskeletal system (injuries of joints, tendons, muscle tissue and ligaments).
Also, the medication in question is actively used for lesions of veins, lymphatic vessels, lymph nodes and skin.
After applying the gel, joint pain is significantly reduced, swelling and morning stiffness are eliminated.
Pharmacokinetics of the drug
What kinetic characteristics does the medicine “Febrofid” (gel) have? Instructions for use states that ketoprofen (the active ingredient of the drug) has good penetration. After applying the gel to the skin, its active component is quickly delivered to the problem tissue, resulting in a local analgesic and anti-inflammatory effect.
The bioavailability of this medicine is at 5%. Communication with plasma proteins is 99%. However , cumulation in the body is not observed.
Ketoprofen metabolism is carried out in the liver.
About 10% of the drug is unchanged and 80% in the form of metabolites are excreted by the kidneys.
Indications
When should I use the drug "Febrofid" (ointment)? Instructions for use indicate the following list of pathological conditions:
- uncomplicated injuries or injuries (including sports bruises, torn ligaments and tendons, sprains, post-traumatic pain syndromes, dislocations);
- painful conditions of the musculoskeletal system, which are inflammatory and degenerative in nature (including arthritis, tendonitis, bursitis, synovitis, lumbago);
- vascular pathologies of an inflammatory nature (phlebitis, periphlebitis), lesions of the lymphatic vessels and lymph nodes (for example, superficial lymphangitis, lymphadenitis) - in complex therapy.
It should also be said that this medication is often used in the symptomatic treatment of myalgia, neuralgia, pain in the spine, etc.
Contraindications
When can you not use the medicine "Febrofid" (gel)? Instructions for use inform us that this drug is not allowed to be prescribed for:
- weeping dermatoses;
- eczema
- breastfeeding;
- infected abrasions, wounds and burns;
- pregnancy (especially in the third trimester);
- hypersensitivity to the main ingredient and other components of the gel, as well as drugs that belong to the NSAID group.
Instructions for use of the drug "Febrofid"
Gel "Febrofid" is designed for external use only.
To achieve the maximum effect of treatment, a small amount of the drug (3-5 cm strip) should be applied to the area of the skin that is located above the damaged area. After this, the medication must be rubbed with light massaging movements.
The application of a dry dressing after the procedure is not required. This is due to the fact that the drug in question is well absorbed, does not include dyes, does not have any smell, and does not leave sticky and greasy stains on clothes.
Side effects
Sometimes, against the background of the use of the drug "Febrofid" in patients, negative manifestations of an allergic nature are observed. These include reactions such as skin hyperemia, photosensitivity, purpura, and skin exanthema.
Drug interaction
With frequent and prolonged use of the drug “Febrofid”, various manifestations of interaction with other medicines can form.
The drug in question increases the content of Verapamil and Nifedipine in the blood.
With the combination of Febrofid with oral anticoagulants, Cefamandol, antiplatelet agents, Cefoperazone, thrombolytics and heparin, the risk of bleeding increases.
The simultaneous use of the gel with glucocorticoids, corticotropin, other NSAIDs and ethanol increases the risk of ulceration and bleeding in the digestive tract.
Joint administration of the drug with insulin and oral hypoglycemic agents increases their hypoglycemic effectiveness.
Ketoprofen worsens the effect of antihypertensive and diuretic drugs due to inhibition of prostaglandin synthesis.
When combined with sodium valproate, platelet aggregation may be impaired.
Special recommendations for the use of an external agent
What you need to know before using the drug "Febrofid" (gel)? Instructions for use informs that this medication should not be applied to areas of skin that are subject to suppuration or mechanical damage. You should also take all precautions to prevent contact with the gel in the eyes.
If it is necessary to use an ointment in a patient with severe pathologies of the kidneys or liver, especially for a long time, it is necessary to constantly monitor his health condition.
If skin rashes are detected, therapy should be discontinued and a doctor should be consulted.
Price and analogues
The cost of the drug “Febrofid” is about 250 rubles per 30 g. You can replace this medication with such means as “Nimulid”, “Diclofenac”, “Ketoprofen”, “Butadion”, “Bystrumgel”, “Indomethacin”, “Artrozilen”, “ Ortofen ”,“ Finalgel ”, etc.
Patient Reviews
Now you have an idea of how to use the drug "Febrofid" (gel). Instructions for use, price, reviews about this tool are described in this article.
Most patients respond to the medication in question solely on the positive side. They claim that this drug quickly and effectively relieves pain, and also eliminates swelling and inflammation in injured areas.
Also, patients note that after applying the gel, it is absorbed quite quickly, without soiling the clothes and leaving no sticky stains on it.
As for negative responses, they are extremely rare. As a rule, the latter indicate the occurrence of allergic reactions in patients.