There are many pathologies that require the use of antiemetics, which relieve the symptoms of nausea and poisoning. This is especially important in the postoperative period, when the body moves away from anesthesia. You also need to prescribe the drug in the process of chemo - and radiation therapy. Such effective remedies include Ondansetron. Analogs (preparations "Emetron", "Latran", "Zofran") will also relieve intoxication symptoms and vomiting in a short time.
The effect of the drug "Ondansetron"
The medicine belongs to the group of antiemetics. Effectively and in a short time relieves nausea and vomiting that occurred in the postoperative period, after chemo - and radiation therapy. The effect of the drug is that it can selectively block serotonin 5-HT3 receptors. As a result, the gag reflexes subside.
After ingestion, the drug is rapidly absorbed in the stomach. Almost 100% binds to blood proteins. The liver lends itself to high metabolism. Within four hours, the medicine reaches its maximum therapeutic effect. Nausea and vomiting pass thanks to the Ondansetron medication. Analogs and substitutes for the drug have the same property and can fully replace the original.
Indications and contraindications
The main indications are the treatment and prevention of nausea and vomiting after chemotherapy and radiation therapy, as well as in the postoperative period. There are several contraindications:
- you can not take medicine in the first half of pregnancy;
- with increased sensitivity to components;
- prescribed with caution in patients with pathology of the kidneys and liver.
Application
The drug is prescribed individually. The daily rate depends on the severity of symptoms, as well as intoxication of the body during radiation and chemotherapy. In the period after surgery, the medicine is prescribed several times a day until the symptoms of nausea and vomiting disappear completely. Only a doctor can prescribe Ondansetron. Instructions for the drug are inside the pharmacy packaging.
It is not recommended to take together with the inducers of the enzyme system of cytochrome, which can lead to clearance and a decrease in the tolerance of the main substance (ondansetron).
You can not prescribe the drug in the first trimester of pregnancy. If you need to use the medicine during lactation, then you need to refuse feeding. Also, patients after surgery on the abdominal cavity should take the drug with caution so as not to hide the symptoms of acute intestinal obstruction. With liver pathology, the dose of 8 mg of the Ondansetron medical product cannot be exceeded.
Analogs and prices, indications and contraindications - all this information should be clarified before treatment.
The price of the drug is about 100 rubles per package.
Side effects:
- headaches;
- coming visual impairment and dizziness;
- pressure reduction;
- tachycardia;
- allergic reactions;
- sensations of heat in the head.
Latran
Refers to antiemetics. Effectively relieves symptoms of nausea and vomiting in the postoperative period, during chemotherapy and radiation therapy. The drug is able to block selective serotonin 5-HT3 receptors. When ingested, the medicine is absorbed in the stomach in a short time. Almost 100% binds to blood proteins. It undergoes metabolism in the liver by hydroxylation.
The maximum availability of the drug is achieved within four hours from the moment the first dose is taken. The Latran medicine has such an effect on the body. The Ondansetron remedy has a similar property. Analogs, synonyms and generics can only be used after consultation with your doctor.
The cost of the medicine is 180-200 rubles in various pharmacies.
Application features
Prevention and treatment of vomiting and nausea in the postoperative period, as well as after chemotherapy and radiation therapy. You can not prescribe a drug in the first trimester of pregnancy and with increased sensitivity to the drug. Also, the drug is not prescribed for liver and kidney pathology. The drug can not be used for poisoning with food or alcohol.
The dose is established individually and taking into account the severity of the disease. The course depends on the symptoms and the presence of intoxication. It can not be taken with tablets, which are inhibitors of the cytochrome isoenzyme system. Without consulting a doctor, it is not recommended to take the Latran drug, as well as the Ondansetron medical product (injection). The instruction describes how to use the medicine for educational purposes only.
Side effects
In most cases, the medicine is well tolerated. The following symptoms may very rarely develop:
- impaired vision and dizziness of a transient order;
- headache;
- bradycardia;
- significant decrease in pressure;
- constipation
- stomach ache;
- feeling of heat.
You can not prescribe a solution or tablets during gestation and breastfeeding. Also, with caution, it is necessary to prescribe after surgery on the peritoneum so as not to miss the symptoms of acute intestinal obstruction. The same measures must be observed during treatment with the Ondansetron drug. Instructions for use, analogs, the correct dosage - all information should be studied before starting therapy, and if you have any questions, consult a specialist.
Zofran
The drug belongs to the group of antiemetic drugs. Effectively relieves symptoms of vomiting and nausea during chemotherapy, radiation therapy and after surgery. The agent can selectively block serotonin 5-HT3 receptors, which reduces the symptom of intoxication. Almost 100% combines with blood proteins. Maximum bioavailability is observed 4 hours after taking the medicine. It is mainly metabolized in the liver by the main substance of the medicine Zofran. Preliminary should be studied, like before using the medicine “Ondansetron”, instructions. Analogs, as a rule, do not differ in composition and indications. Zofran costs about 300 rubles.
Features of use
It is prescribed for treatment and prevention in the period after surgery and chemo- and radiation therapy. You can not take in the first half of pregnancy and during breastfeeding. Also not recommended for hypersensitivity to the drug. The medication cannot be used to stop vomiting and relieve symptoms of intoxication in case of poisoning.
The dose is determined only by the doctor, and it depends on the severity of the patient’s condition after chemotherapy procedures and in the period after surgery. The drug is taken until the symptoms of intoxication disappear completely. Co-administration with isochromic isoenzyme system inhibitors is not recommended. This must be taken into account when treating with Ondansetron. Analogues of the drug can fully replace the original and save the patient from vomiting and nausea.
Side effects:
- coming dizziness and visual impairment;
- headache;
- constipation or diarrhea;
- lowering blood pressure;
- bradycardia;
- abdominal pain.
If any unpleasant symptoms appear, you should consult a doctor for help. The specialist will reduce the dosage or offer a quality substitute.
Emetron
An antiemetic drug that blocks serotonin receptors and has a central effect.
The medicine is in the form of yellow tablets and a solution. The drug is prescribed to eliminate vomiting and nausea after surgery and during chemo and radiation therapy. With intramuscular or intravenous administration, efficacy and a decrease in intoxication are observed for 10 minutes. A solution of the Ondansetron preparation has the same effect. Analogs are very similar in composition.
The price of the drug in some pharmacies exceeds 1200 rubles per package.
Indications and contraindications
It is prescribed to eliminate vomiting and nausea in the period after the operation and during chemotherapy and radiation therapy in children and adults. To eliminate intoxication in case of poisoning, the medication can not be used. There are a number of contraindications for taking:
- pregnancy period;
- lactation;
- age up to 2 years;
- hypersensitivity to active ingredients.
The drug is administered in a dose of 8 to 32 mg per day. The daily norm depends on the severity of intoxication and the individual characteristics of the body. With caution, a medicine is prescribed for patients with pathology of the liver and kidneys. Also, the "Emetron" in low doses is used in old age.
Reviews
In most cases, the drug has positive reviews and is well tolerated by patients. In a short time, removes the symptoms of intoxication of the body, which are expressed in vomiting and nausea. The medicine does not harm the body and can be administered until the symptoms of poisoning disappear completely. According to the reviews of patients and doctors, an allergic reaction to the drug “Ondansetron” may develop. Analogues of the drug can also provoke urticaria and even anaphylactic shock. Therefore, the dosage is established only by a specialist, taking into account the individual characteristics of the patient's body.
The medicine is not addictive and is available in the form of a solution and tablets, which is suitable for the patient with any severity of the process. The described preparations can be used from the age of two. You can buy medicine at any pharmacy. Many doctors recommend such a drug to relieve symptoms of intoxication.
If there is a need to prescribe a drug during breastfeeding, then it is better to abandon lactation. Experts note that the active ingredient passes into milk and may harm the health of the newborn. And, of course, as before taking any drug, a preliminary consultation with a doctor is necessary - then the risk of developing side effects will be minimized.