"Nebilet": instructions for use, reviews, analogues

In case of heart rhythm failure, high blood pressure, you can take (of course, clearly following the instructions) "Nebilet." The drug is based on nebivolol hydrochloride. On sale represented by tablets. From pharmacies dispensed with a doctor’s prescription. The drug has a list of contraindications, it can provoke a negative response of the body, therefore self-medication with its use is strictly not recommended.

Technical information

In the instructions to "Nebilet" the manufacturer indicates what additional components were used to create the drug. Familiarizing yourself with this list is especially important for people suffering from allergic reactions. This will prevent the negative experience of taking the substance. The following components are mentioned in the instructions for the use of Nebilet:

• talc;
• lactose;
• starch component;
• magnesium stearate;
• silicon dioxide;
• polysorbate;
• cellulose;
• sodium salt compounds.

The manufacturer produces a medication in the form of tablets, packed in blisters. One contour package contains 7 capsules or twice as many. In a cardboard box there are instructions for use and Nebilet - tablets packaged in blisters, blisters - from one to four. The specific amount contained inside the preparation is indicated on the outside of the package. Here, the manufacturer writes the name of the drug and the active component on which it works, mentions its dosage. The date of production, expiration date and rules of sale must be indicated (a prescription must be presented).

Pharmacology

The instructions to "Nebilet" indicated that the tablets have three directions of effectiveness:

• against arrhythmia;
• at elevated pressure;
• antianginal.

Proper use of the medication allows for stabilization of high blood pressure. The effect is noticeable both at rest and during exertion (physical, mental). "Nebilet" allows you to lower the pressure in the face of severe stress. The manufacturer describes the mechanism of influence on the patient’s body in the instructions for “Nebilet”.

Under the influence of the active component of the drug, the activity of beta-1-adrenergic receptors is selectively inhibited. The substance can affect both synaptic structures and external ones relative to them. Receptors become immune to catecholamines. Endothelial vasodilating factor is more actively released. The work of renin-angiotensin structures is inhibited, while at the same time there is no effect on renin activity in the blood plasma. This allows you to lower the pressure to normal levels, avoiding the negative effects on the body.

Features of use

In the instructions for the use of "Nebilet", the manufacturer indicates that at the beginning of the course there is a risk of an increase in SPS with a gradual normalization of parameters and a decrease after some time. The effect on pressure is usually observed on the second day of the course, sometimes the wait stretches to the fifth day of the program. A stable result can be observed for at least a couple of months. Under the influence of the active component, the myocardium does not need oxygen so much, angina pectoris is less of a concern, and the attacks themselves are much easier, easier to transfer.

According to the instructions for use, "Nebilet" is recommended to increase resistance to physical activity. Against arrhythmia, the drug is effective due to the correction of cardiac automatism, lowering the level of AV conduction in the opposite direction.

As tests have shown (and this is recorded in the instructions for use), “Nebilet” is absorbed soon after it enters the patient’s body, so the active component penetrates the circulatory system as soon as possible. The quality and speed of the process is not affected by the intake of food in the body. A predominant percentage of the active compound enters into strong bonds with plasma proteins. Transformation processes are localized in the liver. The reaction products have pharmacological activity. Elimination of the active components of Nebilet is performed by the kidneys, intestinal tract.

When will it help?

According to the instructions for use, "Nebilet" is recommended for the following diagnoses:

• Cardiac ischemia.
• High blood pressure.

It is impossible!

The list of contraindications for the use of tablets is much wider than the diagnoses for which it is recommended. According to the instructions, the drug "Nebilet" is not used if installed:

• hypersensitivity to the active component or other substances present in tablets;
• asthma;
• insufficiency of functioning of the heart, liver (especially in severe form);
• low blood pressure;
• cardiogenic shock;
• severe bradycardia;
• angina pectoris;
• depressive disorders;
• myasthenia gravis;
• pronounced muscle hypotension;
• weakness of the sinus node;
• some pathologies of the peripheral circulatory system;
• pheochromocytoma.

Do not use pills in a minor age.

During gestation and lactation, as confirmed by reviews and instructions, "Nebilet" is allowed, but only if it is possible to monitor the patient's condition. Women who took the medication noted that doctors prescribing the drug had previously warned of all the possible negative consequences of such a course. When using tablets in an “interesting” position, the doctor first assesses all the risks associated with the course, the possible positive aspects of therapy, and only with a dominance of benefit decides on the purpose of the medicine.

Negative consequences: what to prepare for?

In the instructions for use with the Nebilet medicine, the manufacturer warns of the possibility of side effects from the medication. Some patients complained that during the course of treatment they were sick and dizzy, while others noted stool disorders. There is a possibility:

• vomiting
• nausea
• paresthesia.

It is possible that the oral mucosa is dry.

In rare cases, while taking the medication, bradycardia was noted, and heart failure developed. The instructions for use and reviews of Nebilet tablets contain references to the following adverse reactions to the drug:

• increased skin sensitivity to light;
• Raynaud's disease;
• bronchial spasm;
• runny nose;
• sleep disturbances;
• craving for sleep in the daytime;
• swelling
• hallucinations;
• depressive states;
• allergy.

Against the background of the use of the drug, hyperhidrosis is possible.

Admission Rules

As indicated in the instructions for use of "Nebilet", 5 mg is the amount of active ingredient in one capsule of the drug. The specific dosage, the amount of substance required for the day, should be chosen by the doctor. On average, 2-5 mg are prescribed. All the recommended amount is used in food daily at a stable time. Taking the drug does not depend on the meal regimen. For better assimilation, the capsules are washed abundantly with clean water without additives.

In the instructions for Nebilet (5 mg), the manufacturer mentions the need for dosage adjustment if the course is prescribed to an elderly person (over sixty-five years old), as well as to persons suffering from kidney failure. At the beginning of the course, such patients are prescribed medicine in an amount of 2.5 mg, gradually adjusting the volumes based on the response of the body.

A dose increase of up to 10 mg per day is allowed.

Too much!

In the instructions for the drug "Nebilet" the manufacturer mentions the possibility of an overdose. She can prove herself:

• pressure reduction;
• cyanosis;
• nausea, vomiting;
• severe heart failure;
• bronchial spasm;
• cardiogenic shock;
• bradycardia;
• coma;
• cardiac arrest.

In accordance with the instructions for the use of Nebilet tablets, if an overdose is detected, it is necessary to rinse the patient’s stomach urgently and give activated charcoal. Additionally, drugs are used based on specific symptoms. If an overdose is detected, it is best to seek emergency medical attention from doctors so that recovery measures, symptomatic therapy are effective and do not become a source of additional harm to health.

Mutual influence

The instruction for Nebilet tablets draws attention to the possibility of cardiodepressive action if you take the medicine at the same time as anesthetics. Such a situation is characterized by a high risk of persistently lowered blood pressure. The deterioration of hypotension is possible when combining the described drug and:

• calcium channel blockers;
• pressure-lowering drugs;
• nitroglycerin.

Medicines that prevent arrhythmias, when ingested with Nebilet tablets, can cause vivid bradycardia. This effect can lead to a combination of drugs and:

• "Reserpine."
• "Guangfacin."
• "Clonidine."

The likelihood of bradycardia with a combination of Nebilet and alpha-methyldopa is increased.

The risk of severe withdrawal is with a combination of the drug in question and agents containing clonidine.

In the instructions for the use of "Nebilet" (reviews confirm that doctors do not recommend such a combination), the manufacturer draws attention to the fact that a decrease in the effectiveness of the drug is possible with its simultaneous use with barbiturates and medicines containing rifampicin. An increase in the concentration of the active compound of the considered tablets in the circulatory system can be observed against the background of the use of drugs with cimetidine.

Features of use

In the reviews of cardiologists, instructions for the use of Nebilet, special attention is paid to the possibility of correction when taking the means of activity of the glands responsible for the production of lacrimal secretions. This fact is especially important for patients using contact lenses. Although the drug itself, according to experts, is reliable, modern, and rarely provokes side effects, doctors pay attention: good results when taking it are achievable only if you follow the instructions and take into account all the specific features of the effect of components on the human body.

It is allowed to use "Nebilet" in the first stage of hypertension, if the persons are allowed to practice flight.

The manufacturer does not indicate in the instructions for use of "Nebilet" at what pressure tablets should be used. This is due to the individual characteristics of the human body. The drug is indicated for high blood pressure, but only a doctor can tell specific indicators by examining the patient’s medical history and individual characteristics of his body. What is high pressure for one is an absolute norm for the other.

What to replace: analogues of "Nebilet"

The instructions for the drug in question indicate that the active component is nebivolol. Popular drugs are based on it:

• "Binelol".
• "Nebivolol."
• "Nebilong."

The last drug is perhaps the cheapest of this group of medicines. According to the instructions for use, the analogue of "Nebilet" called "Nebilong" contains nebivolol and is used with high blood pressure, but strictly under the supervision of a doctor. One package of Nebilong costs about 400 rubles. For comparison: a package with 14 Nebilet tablets will cost the buyer 500 rubles, and with 28 - 900 rubles.

The similarity of some drugs with the medication in question can be concluded not only by studying their instructions for use: reviews of the Nebilet counterparts prove that in some cases these remedies replaced the medication in question for patients.

Before replacing the composition recommended by the doctor, you must first check with your doctor how much the alternative is suitable in a particular case. Some drugs may be cheaper, but often cause adverse reactions, others are not suitable for the patient. The selection of medicines is carried out individually, and the unauthorized replacement of the prescribed drug with an analogue can cause a course inefficiency.

Hypertension: what is it?

Many are used to thinking that high blood pressure is a problem exclusively for the elderly. Unfortunately, in recent years she has become increasingly active in younger years. It is believed that there is a higher chance of encountering it in the presence of a hereditary predisposition, but many people themselves put themselves on the verge of risk: they lead an incorrect and unhealthy lifestyle that adversely affects the work of the heart and blood vessels.

Arterial hypertension - systolic or diastole. The first parameter indicates the pressure parameters at the time of the heartbeat, the second describes the stage of relaxation of the main muscle of our body. Doctors actively use the term “working pressure”. On average, the norm is about 120/80, although the values ​​vary significantly from person to person. Working pressure close to 120/80, at which a person feels good - this is the norm.

With stress (on the psyche, physical, with emotional experiences), the pressure changes. Thus, the body reacts to external factors, compensates for their action, and the body makes the most efficient use of all the resources given to it by nature. Soon after stress or anxiety, joy or effort, the parameters of the circulatory system return to normal on their own, if a person is healthy, the body regulates all systems. But with a frequent increase in pressure, while maintaining such parameters for a long time, in the absence of reasons that could provoke abnormal indicators, it is necessary to consult a doctor for a thorough diagnosis. The doctor will direct the patient to specific tests, based on the results of which he can accurately say what he had to face and how to deal with ill health. You can’t prescribe pills for yourself: even the “Nebilet” described above, although effective, provokes side effects, and the risk of encountering them is much higher for those who take the drug incorrectly.

Pressure: Levels and Classification

About two decades ago, WHO experts developed a classification system for high blood pressure problems. It is she who is currently used both in our country and in other powers.

The pressure 120/80 is considered as close to normal, but deviations upward to 130/85 are allowed. If the indicators are above this boundary, but not significantly (5-10 units), then they speak of a normally elevated parameter.

Arterial hypertension:

• first degree - up to 160/100;
• second degree - up to 180/110;
• third degree - above this indicator.

With a one-time rise in pressure to 150/90, after which the body independently returns to normal, they talk about the borderline degree of the disease.

An isolated form is possible when only the first indicator is higher than normal, and diastole is estimated at 90 or close to this figure. Systole in this case is more than 140 units.

At the first stage of hypertension, there are no specific organic changes in target organs, but over time, the disease progresses. In the second stage, deformation of one or more organs is possible. Such patients are a risk group for hypertensive crisis. At the third stage, violations of the structures of the internal organs are numerous, and the patient is at risk for health problems:

• stroke;
• optic nerve degeneration;
• heart attack;
• kidney failure.

Causes and consequences

All cases of hypertension are usually divided into primary, secondary. Tactics of treatment is chosen based on belonging to one of these groups. Primary - this is increased pressure, an independent disease, called essential. Secondary develops against the background of other diseases and is their symptom. Doctors say that secondary occurs on average in only one in ten hypertensive patients, but the predominant percentage of cases is precisely the essential form. To this day, it was not exactly possible to establish its causes, although some factors provoking the disease were identified. These include:

• lack of motor activity in everyday life;
• excess weight (up to 85% of obese - hypertension);
• high cholesterol;
• lack of potassium in the body;
• calciferol deficiency;
• hypersensitivity to salt;
• smoking;
• alcohol abuse;
• frequent, severe stresses, inadequate response to them, increased susceptibility.

Secondary hypertension is observed if pathological processes affect the internal organs responsible for pressure.

In each individual case, hypertension is usually the result of several aggressive factors. Having identified all of them, having established predispositions for various health disorders, especially the daily routine of a person, a doctor can develop an optimal course of combating the disease. It will include both medications (for example, Nebilet tablets), and additional activities - diet, lifestyle changes.

It is known that almost every third (according to some estimates, every fourth) resident of our planet suffers from hypertension. To a greater extent, the disease affects people over 65 years old - in this age group, increased pressure was found in every second. Up to the age of forty, hypertension is more common among men, and among people over the age of 40, women predominate. , , , .

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How to notice?

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• dyspnea;
• nausea, vomiting;
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The signs are nonspecific, therefore they rarely attract attention, more often people attribute them to weather phenomena, overwork and feelings.

We’ll check everything!

If you succeeded in time to suspect hypertension and consult a doctor, you will have to undergo a comprehensive examination. The doctor identifies what factors could be the cause in this case, how to deal with them, which systems and organs have already suffered from pathological processes.

The most basic check is taking a tonometer (mechanical, electronic). Such devices should be at home for everyone and everyone, especially if there are people in the family who suffer from high or low blood pressure.

At the reception for symptoms that allow to suspect hypertension, the doctor collects patient complaints to compile a picture of the disease, identifies which risk factors are relevant for a particular case. Check the family history of the disease for similar cases in close relatives.

The doctor dries out the heart sounds, prescribes an electrocardiogram, a general blood test and biochemistry, a hormonal check. Additionally, an ultrasound study of the heart muscle is done, revealing the thickness of the muscle tissue, the state of the valves. An obvious sign of hypertension is an enlarged left ventricle in excess of the norm. To identify secondary disorders using ultrasound study the condition of the liver, kidneys, vascular system, thyroid gland.

If hypertension is suspected, the patient is referred to an ophthalmologist to assess fundus health. Often high blood pressure provokes a wide range of ophthalmic diseases. To identify the specificity of blood flow in the carotid arteries, Doppler measurement is prescribed. The vessels of the brain are checked by the same method.

In some cases, the doctor prescribes highly specialized tests.

What to do?

The therapeutic course for hypertension includes several approaches, both medicinal and alternative. A comprehensive scheme is developed by the doctor, based on the individual characteristics of the patient's condition. Select the appropriate drugs - for example, the “Nebilet” described above, transfer the patient to a low-fat diet, and recommend regular exercise as part of the reasonable. With hypertension, you will have to abandon bad habits, establish a daily regimen, and avoid stressful situations.

The drugs prescribed for hypertension are designed for a short course, but most of the drugs are designed for prolonged, sometimes life-long use. The doctor will give specific recommendations regarding the course format, dosage, frequency of use and the possibility of combining different substances. In addition to Nebilet, the doctor usually recommends a course of diuretics, sedatives. Additionally, they may be advised to use traditional medicine recipes - many herbs soothe well, help stabilize the condition and reduce the amount of medicines used.