We will consider the Tenorik preparation instructions for use, reviews and analogues. It is a combination drug that can be attributed to the pharmacological category of antihypertensive drugs used to treat symptoms of high blood pressure.
Dosage form and composition of the drug
According to the instructions, "Tenorik" is available in tablet form. The tablets have a rounded configuration; they are biconvex, with a white tint; enteric coated film coating. The drug content is the two main active components, which are atenolol and chlortalidone.
In addition, in accordance with the instructions, Tenoric tablets also contain some auxiliary substances. These include:
- hypromellose;
- lactose;
- magnesium stearate;
- titanium dioxide;
- methylene chloride;
- talc;
- corn starch;
- Vaseline oil;
- macrogol;
- isopropanol;
- colloidal silicon dioxide;
- polyvinylpyrrolidone;
- sodium lauryl sulfate.
As the instruction "Tenorik" indicates from pressure, it is packaged in blisters, each of which contains 14 tablets. Blisters of 2 pieces are packed in a cardboard box, which also includes instructions for using this medication.
Therapeutic effects
In accordance with the instructions, "Tenorik" contains substances that help to reduce high systemic blood pressure due to its complex medicinal effect.
Atenolol is a beta-blocker that selectively suppresses the activity of certain adrenergic receptors of blood vessels and the heart, as a result of which smooth muscles are relaxed and the lumen of the vessels widens with a decrease in blood pressure. In addition, this substance helps to reduce the frequency of contractions of the heart, as well as shock and minute volumes, due to which the patient lowers blood pressure. This is described in the Tenorik manual. 50 mg is the standard dosage.
Chlortalidone, which is also part of the drug, is a thiazide diuretic (diuretic), which increases urine excretion, resulting in a decrease in the total volume of circulating blood and, consequently, blood pressure.
With the combined effect of these medicinal substances, their therapeutic effect is summarized. After taking one tablet of the medicine “Tenorik”, the active substances of this medicine are absorbed into the blood from the intestinal lumens, and the bioavailability is more than 50%. After this, the active substances enter the bloodstream and begin to be evenly distributed in the tissues of the body. They practically do not undergo the action of metabolism and are excreted unchanged with feces and urine.
What else does the instruction for Tenorik tell us?
Indications for use of the drug
The only indication for the use of this medication is systemic and periodic arterial hypertension (increased levels of blood pressure).
Contraindications
Taking the drug is contraindicated in certain concomitant physiological and pathological conditions, which include:
- Cardiogenic shock, which is characterized by a sharp decrease in the contractile functions of the myocardium, accompanied by a critical decrease in the intensity of blood flow in the arteries, as well as pressure.
- A pronounced decrease in the number of heart contractions (bradycardia).
- Metabolic acidosis, which is a shift in blood reactions to the acid side, which is usually associated with metabolic disorders.
- Severe changes in blood circulation in the peripheral vessels.
- Blockade of the atrioventricular (atrioventricular) node of the second or third degree. This is confirmed by the instructions for use with the blue Tenorik.
- Syndrome of weak function of the sinus node of the heart with insufficiency of the formation of a heart pulse.
- Acute and severe forms of heart failure.
- A hormone-producing tumor of the brain substance in the adrenal glands (pheochromocytoma), which leads to an increase in the adrenaline level in the blood, without appropriate therapy.
- Chronic forms of heart failure, which are accompanied by congestive blood events.
- Vasospastic forms of angina pectoris with periodic narrowing of the coronary (cardiac) arteries.
- Obstructive form of bronchitis - with inflammation of the bronchial mucosa with impaired air patency in them.
- Bronchial asthma, which is a specific allergic inflammatory process in the bronchi, with their periodic spasms.
- Diabetes mellitus, which is a violation of the carbohydrate metabolism in the body.
- Hepatitis is an acute form of the inflammatory process in the liver.
- Violation of the metabolic functions of purine bases (gout).
- Muscle weakness (myasthenia gravis).
- Acute forms of renal failure.
- Individual intolerance or high sensitivity to certain substances contained in the drug.
- The patient's age is up to 18 years.
Before using "Tenorika" 50 mg according to the instructions for use, you need to make sure that there are no contraindications in the patient.
Ways to use the medicine and dosage
The medicine is intended for oral administration (oral).
According to the instructions, "Tenorik" can be drunk regardless of food, most often - once a day, at the same time. Tablets should not be chewed and crushed. Drink the medicine with a sufficient amount of liquid. The initial dosage for an adult is 50 mg of the active substance per day. With an insufficient decrease in blood pressure, the dosage can be increased to 100 mg of atenolol per day.
Such a dose, as a rule, is sufficient to obtain the necessary therapeutic response.
What else does the instruction for Tenorik tell us?
In case of insufficient decrease in blood pressure, a subsequent increase in the dosage of tablets is considered inappropriate. In this case, the drug can be used in combination with other antihypertensive drugs (angiotensin converting enzyme inhibitors or calcium channel blockers). The duration of treatment with this medication is very long, and in most cases the medicine is prescribed for life.
Adverse reactions from the use of the medication
In accordance with the instructions and reviews of "Tenorik" in some cases, the development of certain pathological reactions from different systems and organs may be observed:
- Digestive system - dyspeptic disorders, accompanied by bloating (flatulence) and dry oral mucosa.
- Nervous system - headaches, the occurrence of periodic dizziness, confusion, sudden changes in mood, sleep disturbance, hallucinations and cases of acute psychosis can rarely be observed.
- Cardiovascular system - inhibition of the frequency of heart contractions (bradycardia), increased symptoms of insufficiency of heart function, a marked decrease in blood pressure when a person changes his body position (from horizontal to vertical), a change in the passage of cardiac impulses through the atrioventricular division.
- Red bone marrow and blood - neutropenia (a decrease in the number of neutrophils), leukopenia (a deficiency of leukocytes), thrombocytopenia (a decrease in the number of platelets), agranulocytosis (granulocyte deficiency), as well as a sharp increase in the number of eosinophils (eosinophilia) in the blood.
- The respiratory system is bronchospasm (narrowing of the gaps of the bronchi), which is often observed in patients suffering from bronchial asthma.
- Mucous membranes and skin - alopecia (hair loss), exacerbation of psoriasis symptoms, dry eyes, skin rashes, photosensitivity (increased sensitivity to light).
- The reproductive system is a decrease in potency in men.
- Laboratory research indicators include an increase in uric acid levels in the blood (hyperuricuria), as well as a decrease in the amount of sodium ions in it (hyponatremia).
If the above signs of negative pathological effects from the use of the drug occur, the need to stop taking the medication, or change its dosage, is determined by a specialist.
The instructions for the Tenorik tablets are very detailed.
Special recommendations
Before using the medication, a specialist should carefully familiarize himself with the medical history of a particular patient, taking into account the characteristics of the body, the presence of allergic reactions to a particular drug substance, and also taking into account some special recommendations regarding the appropriate use of the drug. Similar recommendations in the instructions for use include the following:
- The drug should be used with caution in patients with concomitant atrial ventricular blockade of the first degree.
- The use of Tenorik tablets due to a decrease in pressure can lead to a decrease in the manifestations of hypoglycemia and hyperthyroidism.
- If the heart rate decreases to 50 beats per minute or less, the use of this medication should be suspended or its dosage reduced.
- In patients suffering from nicotine addiction, a decrease in the therapeutic effect of treatment with a medication is possible.
- It is not recommended to abruptly discontinue the drug, as this can cause a "withdrawal" syndrome, accompanied by a sharp increase in blood pressure. The abolition of the use of this medical device is carried out by methods of gradual reduction of its dosage.
- In the case of a planned surgical intervention, the use of the medication is stopped two days before its implementation.
- The drug “Tenorik” can provoke the occurrence of various allergic manifestations, therefore, it is prescribed with extreme caution to people suffering from any form of allergy, especially in cases where patients have had allergic bronchospasms in the past.
- Against the background of taking the medicine “Tenoric”, a decrease in the number of potassium ions in the blood is possible, which implies periodic laboratory monitoring of such indicators.
- Since the medicinal product contains a diuretic, against the background of its use, a decrease in the production of tear fluid may be observed, which must be taken into account if the patient uses contact lenses.
- Against the background of decreased kidney function, the drug should be used with extreme caution.
- Patients who have a predisposition to diabetes mellitus, the drug "Tenorik" 100 according to the instructions is prescribed with caution.
- The active substances of these tablets can interact with a large number of other drugs of various pharmacological groups, therefore, in cases of their use, it is necessary to inform the attending specialist.
- Since this drug can increase the level of uric acid in the blood, after laboratory monitoring, additional prescription of medications is possible, contributing to its rapid elimination.
- In the treatment with the drug "Tenoric" is not recommended to perform work associated with an increased rate of psychomotor reactions and high concentration of attention.
- In the pharmacy network, these tablets are dispensed exclusively by prescription from a doctor. Their independent use without the appointment of a specialist is not recommended.
- When treating with this drug, you can’t take alcoholic beverages, as this can cause a sharp decrease in pressure and increase the manifestation of side effects. This can be confirmed by the instructions for use with the drug "Tenoric".
Excessive Dose
If the dosage of the “Tenoric” medical device is exceeded, the blood pressure, the intensity of the heart contractions decrease, and the development of acute forms of heart failure, loss of consciousness, bronchospasm is also possible. In such cases, pathogenetic and symptomatic therapy is carried out in a hospital with constant monitoring of vital indicators.
We examined the medicine "Tenoric" and its instructions.
Drug Analogs
The following medications have a similar therapeutic effect and composition:
- Tenorox.
- "Tenorm".
- Tenoretik.
- Atenol.
- Dinoric.
- "Atenolol".
- Ventavis.
- Corvitol.
- "Trifas".
- Arifon Retard.
- "Bisoprolol."
- Biprol.
The question of which drug to buy instead of the means described by us should be decided jointly with the doctor. Self-medication is unacceptable and fraught with serious health consequences.
Reviews about the drug
Numerous reviews about the drug "Tenorik", left by patients, as well as specialists of medical institutions, indicate that this medication is currently widely used for the treatment of arterial hypertension.
Patients note that this medication acts more gently than other antihypertensive drugs, and its use is very advisable in the initial stages of the development of hypertension. After its use, blood pressure returns to normal after a rather short period of time, which is why patients are very satisfied.
When using honey. the preparation "Tenorik" according to the instructions in cases of an advanced pathological condition associated with an increase in pressure, a slight decrease is noted, which indicates that the drug is not strong enough to use it in the late stages of the disease. This is also evidenced by the reviews of patients who were prescribed this medication at the initial stages of therapy. They argue that after the use of this remedy did not produce positive results, it was replaced with other, more powerful drugs.
In addition, the patient reviews reflected some information about the side effects of the drug "Tenorik". It is indicated that some time after taking the pill, people had bouts of acute headache, dyspepsia, dizziness and bradycardia. In this regard, they had to contact a specialist for adjusting the dosage of the drug.
In general, many experts note that the drug is very effective for use in cases of a single decrease in blood pressure, or in situations associated with stress, excessive physical exertion, etc., that is, in single, non-systemic cases of hypertension illnesses. Patients suffering from just such phenomena on the part of the body also confirm this and note that in such situations, the drug was very effective.
The article was presented to the tool "Tenoric" instructions and reviews.