In the article, we consider the instructions for use with "Methyluracil" in suppositories, tablets and in the form of an ointment.
A pharmacological agent is a medicine from the clinical-pharmacological group of leukopoiesis stimulants (the process of formation and maturation of leukocytes). Also, this medicine activates metabolic processes and tissue nutrition, stimulates their regeneration. It is used for leukopenia and various pathological conditions that are accompanied by damage to tissues and cells.
Release form and composition
Instructions for use with Methyluracil are very detailed. To date, the medicine is made in three forms: tablets, suppositories and ointment.
According to the instructions for use, the ointment "Methyluracil" is available in tubes of aluminum with a volume of 25 g, tablets are packaged in convolutes of 100 or 50 pieces, and candles - in packs of 10 pieces. In all forms of this drug, the substance methyluracil is present as the active element. As additional components, candles and ointment contain alcohol, paraffin and macrogol, and tablets contain potato starch, calcium stearate, povidone and talc.
Pharmacological properties
As indicated by the instructions for use with "Methyluracil", the main active substance of the pharmaceutical agent has anabolic effects, stimulates the formation of organic compounds in cells, resulting in a number of therapeutic effects:
- stimulation of leukopoiesis and hematopoiesis, which consists in increasing the number of formed elements (white blood cells and red blood cells) in a unit of blood;
- immunostimulating effect - increased activity of all structures of the immune system;
- acceleration of regenerative processes in tissues in case of damage as a result of stimulation of the processes of epithelization and granulation of tissues.
There are currently no accurate clinical data on the absorption, distribution, metabolism and excretion of the active element of this medicine.
Indications for appointment
Reception of tablets "Methyluracil" according to the instructions for use is indicated for the following pathological processes:
- Leukopenia is a decrease in the number of leukocytes in the blood, which has a different nature of origin, including that induced by the use of certain pharmaceuticals, chemotherapy and radiation therapy for the development of malignant neoplasms.
- Agranulocytic tonsillitis, which is a septic pathology, which can lead to severe depletion of the immune system and the disappearance of granulocytes from the blood (eosinophils, neutrophils, basophils).
- Thrombocytopenia is a decrease in platelet count in the blood.
- Anemia is a low level of hemoglobin and red blood cells in the blood, which can be triggered by a variety of reasons, including the toxic effect of some chemical compounds and drugs on the bone marrow.
- Benzene intoxication, which interferes with the processes of formation and maturation of cell structures in the bone marrow.
- Radiation sickness, developing as a result of exposure to ionizing radiation and characterized by damage to the bone marrow.
- Recovery from severe infectious diseases.
- Fractures, wounds, conditions after burns, when there is a slow healing of tissues.
Instructions for use with the tablets "Methyluracil" must be strictly observed.
In addition, this drug is used as part of a combined therapeutic course for peptic ulcer, hepatitis and pancreatitis.
In accordance with the instructions for use, Methyluracil suppositories are prescribed for diseases such as ulcerative colitis, proctitis, sigmoiditis, hemorrhoids, proctosigmoiditis, anal fissures, colpitis.
The ointment is prescribed for poorly healing deep wounds, trophic ulcers, pressure sores, diaper rash, burns, dermatitis, photodermatosis, radioepithelitis, radiation damage to the vagina.
According to the instructions for use, Methyluracil is also used in gynecology.
The use of the drug in gynecology
Due to the fact that the main substance of this medication helps restore cell structures, gynecology uses suppositories of this medication to heal sutures, wounds and eliminate the inflammatory process in the genital area. Thus, the main indications for the appointment are the following pathologies:
- colpitis;
- vaginitis;
- injuries of the vaginal walls and cervix;
- cervicitis;
- ectropion;
- vulvitis;
- cervical erosion;
- cystitis.
Mainly used candles "Methyluracil" in gynecology. Instructions for use with them confirms this.
Contraindications
Taking the medication is contraindicated in the following pathological conditions:
- intolerance to the existing or additional elements of the drug;
- myeloid forms of leukemia, which are characterized by the formation of a large number of tumor blood structures in the bone marrow;
- lymphogranulomatosis, which is a tumor of lymphocytic bone marrow growths;
- hemoblastosis - a tumor lesion of cells that are the precursors of red blood cells:
- malignant bone marrow.
The drug is not prescribed for the treatment of children under 3 years.
Dosage and route of administration
As indicated by the instructions for use with Methyluracil, the tablets are taken orally with food. The therapeutic dosage depends on age:
- 3-8 years - 250 mg 3 times a day;
- 8-14 years old - 250-500 mg 3 times;
- over 14 years old and adults - 500 mg 4 times.
For the treatment of gastrointestinal pathologies, namely peptic ulcer, the course of therapy should last at least 30 days.
The drug in the form of rectal suppositories is indicated for use during an exacerbation of pathological conditions (with inflammation of hemorrhoids, the presence of bleeding and cracks in the mucous membrane). When used in proctological practice, they are prescribed for introduction into the rectum in the amount of 1 pc. 3 times a day.
Ointment is applied in a volume of not more than 20 grams. for one application, it is applied twice a day for a month.
Side effects
In general, the pharmacological agent “Methyluracil” is well tolerated, however, in some cases, allergic reactions, heartburn and dizziness may occur.
Special recommendations
Before starting treatment with the drug "Methyluracil", you must carefully read the annotation on its use. There are several specific recommendations regarding taking the drug:
- During pregnancy and the lactation process, the use of this pharmacological agent is possible only by prescription.
- The drug is not prescribed for children under 3 years.
- The medicine does not directly affect the speed of mental and motor reactions and the possibility of concentration.
In the instructions for use with "Methyluracil" price is not indicated.
Price
Depending on the pharmacological form of release, this medication can cost from 20 to 40 rubles per package.
Analogs
According to the active substance and therapeutic effect for the drug, the following medications are similar:
- "Kolartek";
- Prelax
- "Stizamet";
- Softovak;
- Esculex
- "Hemorol";
- "Venolek";
- "Diovenor";
- Daflon
- "Diosmin";
- "Provin";
- Aescin;
- "Bezornil";
- Maclura;
- Sedum.
Reviews
This medication at the moment of the development of the pharmaceutical industry is in great demand among consumers and is often prescribed by specialists. There are many reviews of this medicine and most of them are positive. Patients to whom it was prescribed, note its high effectiveness in the treatment of a variety of skin lesions, diseases of the digestive tract, in particular the stomach. Many women use it for various gynecological problems and are also very pleased with the effect.
Some reviews contain information that this medication can cause negative reactions in the form of nausea, but this phenomenon is not indicated in the instructions for use of the drug.
The reviews of doctors talk about the safety and good tolerability of the drug. Experts say that this tool is almost indispensable for many diseases, and is prescribed both as an independent medication and as part of complex therapy.
We reviewed the instructions for use with Methyluracil.