The drug "Betamethasone", analogues of the drug (for example, the drug "Diprospan") belong to the category of glucocorticosteroids for local and systemic use. Medicines have antipruritic, anti-inflammatory effects, have anti-allergic and glucocorticoid effects. Betamethasone (the instructions for use contains this information) is able to interact with specific receptors in the cell cytoplasm. The formed complex penetrates the cell nucleus, interacts with DNA and activates the synthesis of mRNA. The medicine has an effect on different phases of inflammation. Due to the stabilization of cell membranes, the concentration of lysosomal enzymes decreases, their output is prevented. The medication is able to improve microcirculation, reduce vascular permeability, provoke vasoconstriction in the capillaries, and reduce fluid exudation. By reducing the synthesis and production of allergy mediators, an anti-allergic effect is manifested. The drug "Betamethasone" (reviews of doctors confirm this) has, among other things, anti-toxic, anti-shock effect, has an immunosuppressive effect.
Indications
The drug is recommended for shock conditions against burns, injuries, operating, cardiogenic, toxic, anaphylactic, blood transfusion type. Indications include anaphylactoid and allergic reactions (severe and acute), swelling in the brain (due to tumors and injuries), bronchial asthma. The medication Betamethasone recommends the use instructions for systemic pathologies in connective tissue, systemic lupus erythematosus, rheumatoid arthritis, thyrotoxic crisis, acute adrenal insufficiency , hepatic coma, and acute hepatitis.
The
drug is prescribed
for poisoning with cauterizing fluids and compounds (to prevent inflammation and scarring). Intra-articular agent is administered for rheumatoid arthritis, osteoarthritis,
ankylosing spondylitis, Reiter’s
disease . Orally (in tablet form), Betamethasone is recommended for use in case of systemic pathologies in connective tissue, periarteritis nodosa, acute, inflammatory joint pathologies, allergic rhinitis, Quincke’s edema, contact dermatitis, allergic reactions when taking medications and other conditions.
Contraindications
Means "Betamethasone" (instructions for use warns about this) is not recommended for hypersensitivity. If necessary, for short-term use for health reasons, intolerance is considered the only contraindication. Orally and parenterally, the drug is not prescribed for herpetic lesions, systemic mycoses, tuberculosis, immunodeficiency states, pathologies in the gastrointestinal tract. Contraindications include congestive heart failure, acute psychosis. Intra-articular preparation is contraindicated for instability in joints, pathological bleeding, intra-articular infections. Outwardly, no medicine is prescribed for tuberculosis, syphilitic skin lesions, post-vaccination reactions, rash in children up to a year old due to diaper rash and other conditions.