The article will focus on a drug called Kaffetin. Tablets have a number of effects, which include:
- psychostimulant;
- painkiller;
- antipyretic;
- antitussive;
- anti-inflammatory.
Most often it is used for headaches. Like all medicines, Kaffetin has indications and contraindications, side effects and incompatibility with certain medications. You can find out all this by reading this article. In addition, you need to know that Kaffetin and Kaffetin Light (which will be discussed in the article) are slightly different in composition. The first contains codeine, and the second does not.
Composition and form of release
In this section, you will learn about what Caffetine is (tablet composition, release form). To begin, we will analyze the composition, it is more convenient to arrange it in the form of a table. In the left column are substances, and in the right - their content in milligrams.
Paracetamol | 250 |
Propiphenazone | 210 |
Caffeine | fifty |
Codeine Sesquihydrate Phosphate | ten |
Glyceryl dibehenate | 6.3 |
Calcium Hydrogen Phosphate Dihydrate | 21.1 |
Sodium carboxymethyl starch | 14.5 |
Colloidal anhydrous silica | 2,5 |
Croscarmellose sodium | 9.6 |
Magnesium stearate | 13.5 |
Sodium lauryl sulfate | 1,5 |
Povidone | 12.5 |
Microcellulose | 28.5 |
When buying, pay attention to the packaging, if it is damaged, then you should not use the drug. In order to check the tablets for originality, pay attention to the inscriptions, color and number of tablets in one plate. They should look like this:
- flat, round;
- White colour;
- engraving - β5β, Caffetin;
- in one strip there can be six or ten tablets;
- in a carton box there is one strip if it contains ten tablets, or two if they contain six tablets.
Pharmacodynamics
"Caffetine" (tablets), which is discussed in this article, as it has already become clear, is a combination drug. Each component element performs a specific function. Paracetamol has the following effects:
Caffeine, which is part of the drug, is capable of:
- stimulate the brain;
- enhance the analgesic effect of paracetamol;
- reduce drowsiness;
- remove fatigue;
- increase efficiency;
- increase heart rate;
- increase blood pressure.
Codeine is able to relieve cough. This becomes possible due to the suppression of the excitability of neurons of the cough center in the central nervous system. Like paracetamol, codeine is an analgesic that can alter the emotional perception of pain.
There is a substance in the table called propiphenazone, which helps get rid of pain and lower body temperature. The analgesic effect occurs an hour after taking the drug, but lasts about eight hours.
Pharmacokinetics
Now we discuss the pharmacokinetics of the drug "Kaffetin." The tablets in the composition have common paracetamol, which is instantly absorbed. Its maximum concentration in the blood is observed 30 minutes after administration. Metabolism can occur in three ways in the liver:
- conjugation with glucuronides;
- sulfate conjugation;
- oxidation.
It is excreted after four hours through the kidneys in the form of metabolic substances.
The peculiarity of caffeine is that it is absorbed in all parts of the intestine. It easily penetrates the placenta. The maximum caffeine content in the blood is observed 1 hour after taking the medicine. This substance spreads very quickly throughout the human body. Caffeine is metabolized in the liver, excreted through the kidneys after five and a half hours.
Codeine is also a feature of fast absorption. In plasma, its maximum concentration is reached 2 hours after administration. The substance is excreted by the kidneys, it can come out with bile after 4 hours.
The substance propiphenazone is absorbed in the digestive tract. It can be detected in the blood 50 minutes after administration. It is excreted in the bile or urine after two hours.
Indications
In this section you can find out what are the indications for the use of Caffetin Light. Instructions for use (tablets) say that the remedy can be taken for certain diseases and painful sensations, namely:
- headache;
- toothache;
- migraine;
- neuralgia;
- myalgia;
- post-traumatic pain;
- arthralgia;
- algodismenorea.
Indications for the drug "Kaffetin" are the same. It is necessary to take into account the fact that the drug contains caffeine, which increases physical and mental activity. That is, it is not recommended to use it before bedtime. You can drink a Koffetin tablet in cases where the pain syndrome is moderate. Any source can have pain.
Contraindications
Like all medicines, Caffetine in tablets has its contraindications. Instructions for use of this drug states that in certain certain cases, the drug can not be used. In this section, we will get acquainted with contraindications to the drug. These include:
- hypersensitivity;
- liver failure;
- renal failure;
- leukopenia;
- bleeding disorders;
- anxiety disorders;
- diseases of the cardiovascular system;
- sleep disturbances;
- pregnancy;
- lactation period;
- age under eighteen.
The above cases are related to a strict ban on the use of this drug. At risk are also people who:
- felt a sharp pain in the abdomen and do not know its cause;
- suffer from asthma;
- have chronic lung disease;
- who have cramps;
- having drug addiction;
- suffer from alcoholism;
- who have increased excitability;
- having viral hepatitis;
- elderly age.
In these cases, before taking the drug, you must always consult a doctor.
Side effect
Kaffetin Light tablets, like Kaffetin, can also have side effects. Remember that all medicines must be used strictly according to the instructions, which is in the box with the medicine. Do not self-medicate, consult with a specialist before taking. Even the most harmless drugs can be harmful if you neglect the rules for their use. So, the side effects of the drug "Kaffetin" include:
- increased excitability;
- tremor;
- anxiety;
- insomnia
- heart rate increase;
- increase in pressure;
- exacerbation of an ulcer;
- nausea
- vomiting
- skin rash;
- urticaria;
- itching
- swelling of the face;
- bronchospasm;
- laryngeal edema.
They can occur together or separately. Side effects are quite rare. If any of the symptoms listed above have manifested themselves, then you should definitely inform your doctor. He will tell you how to deal with the problem, and may recommend a more suitable drug.
"Kaffetin": instructions for use
Kaffetin tablets, like all other medicines, must be used strictly according to the instructions so as not to cause an overdose of the drug. The maximum daily dose is six tablets.
The duration of treatment should not exceed five days. However, the attending physician may increase the daily dose and course of treatment. Without the recommendation of your doctor, these actions can not be performed.
Overdose
Mostly take these pills for headache. Caffetine should be drunk strictly in accordance with the instructions. Each component in an overdose manifests itself in different ways. If the norm of paracetamol is exceeded, then the following symptoms are possible:
- pale skin;
- nausea;
- vomiting
- impaired liver function.
This may occur a day after taking the drug. If the dose of caffeine is exceeded, the following are possible:
- anxiety state;
- tremor;
- headache;
- confusion.
If the dosage of codeine is exceeded, then the following symptoms appear:
- cold and clammy sweat;
- dizziness;
- drowsiness;
- pressure reduction;
- nervousness;
- fatigue;
- weakness;
- labored breathing;
- anxiety;
- cramps.
If you notice overdose symptoms, then you need to urgently call an ambulance. Do not try to rinse your stomach yourself. This is not enough, it is necessary to normalize heart activity and blood pressure.
Caffetine forte tablets: interaction
The instructions for this drug say that Kaffetin should not be used together with the following drugs:
- barbiturates;
- with drugs for epilepsy;
- rifampicin;
- zidovudine;
- ethanol.
It has already been mentioned that paracetamol is part of the product, it contributes to the fact that the complete elimination of chloramphenicol increases five times. The presence of caffeine leads to improved absorption of other substances. And codeine enhances the effects of analgesics and sleeping pills.
Sale, storage, price and special instructions
This drug is dispensed from a pharmacy strictly by prescription. Kaffetin is stored in a dark place, away from children. The room temperature should not exceed 25 degrees Celsius, and also be less than 15. The shelf life of the drug is three years.
When taking this medication, you should abandon the use of alcohol. Kaffetin can slightly distort the test results. Athletes should be aware that the drug changes the results of the doping control. The price of the product is approximately 115 rubles.
Reviews and analogues
"Caffetin" - pills that help eliminate pain. Analogs can serve:
- "Paracetamol" (from 18 rubles).
- "Trigan-D" (from 70 rubles).
- "Solpadein" (from 140 rubles).
Reviews about this drug are extremely positive. Rare cases of dizziness and nausea were noted.