Stevens Johnson Syndrome

Stevens-Johnson Syndrome is a very serious skin disease, a malignant type of exudative erythema, in which severe redness appears on the skin. At the same time, large blisters appear on the mucous membranes and skin. Inflammation of the oral mucosa makes it difficult to close your mouth, eat, drink. Severe pain provokes increased salivation, shortness of breath.

Inflammation, the appearance of blisters on the mucous membranes of the genitourinary system complicates the natural administration. Urination and sexual intercourse become very painful.

Most often, Stevens-Jones syndrome occurs as a response to an allergic reaction to taking antibiotics or drugs designed to treat bacterial infections. Representatives of medicine are inclined to the fact that the tendency to the disease is inherited.

The cause of the exacerbation may be, according to scientists, several factors.

Most often, Stevens-Jones syndrome occurs as a response to an allergic reaction to taking antibiotics or drugs designed to treat bacterial infections. The reaction can cause drugs from epilepsy, sulfonamides, non-steroidal painkillers. Many drugs, especially those of synthetic origin, also affect the onset of symptoms that characterize Stevenson Johnson syndrome.

Infectious diseases (influenza, AIDS, herpes, hepatitis) can also provoke a malignant form of exudative erythema. Fungi, mycoplasmas, bacteria that enter the body can provoke an allergic reaction

Finally, symptoms are very often recorded in the presence of cancer.

More often than others, Stevens Johnson's syndrome manifests itself in men from twenty to forty years, although the disease was recorded in women, children up to six months.

Since the disease belongs to instant allergies, it develops very quickly. It begins with severe malaise, the appearance of unbearable pain in the joints, muscles, a sharp increase in temperature.

After a few hours (less often - days), the skin becomes covered with silvery films, deep cracks, blood clots.

At this time, bubbles appear on the lips and eyes. If initially an allergic reaction in the eyes comes down to their intense redness, then ulcers and purulent blisters may appear later. The cornea, posterior parts of the eye become inflamed.

Stevens-Johnson syndrome can affect the genitals, causing cystitis or urethritis.

A general blood test is required for diagnosis. Usually, in the presence of a disease, he shows a very high white blood cell count, rapid erythrocyte sedimentation.

In addition to the general analysis, it is necessary to take into account all the preparations, substances, food that the patient took.

Treatment of the syndrome usually involves intravenous transfusion of blood plasma, drugs that cleanse the body of accumulated toxins, the introduction of hormones. To prevent the development of infection in ulcers, a complex of antifungal and antibacterial drugs, antiseptic solutions are prescribed.

It is very important to follow a strict diet prescribed by a doctor, drink plenty of fluids.

It has been statistically established that with a timely visit to a specialist, the treatment ends quite successfully, although it takes a lot of time. Therapy usually lasts 3-4 months.

If the patient has not started receiving medical treatment in the early days of the disease, then Stevens-Johnson syndrome can be fatal. 10% of patients die due to late treatment.

Sometimes after treatment, especially if the disease is severe, scars or spots may remain on the skin. The occurrence of complications in the form of colitis, respiratory failure, impaired functioning of the genitourinary system, blindness is not ruled out.

This disease absolutely excludes self-medication, as it is potentially fatal.


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