In the article, we consider the instructions for use and reviews for the Klion-D 100 medication.
Trichomonas and fungal infections appear in women very often. The reasons for this can be very different, ranging from weakened immunity and heredity, ending with random and unprotected intimate relationships. Among the many drugs, one of the best is Klion-D 100. This drug locally fights infections, producing a drug effect. In the article we will get acquainted with the instructions for using these vaginal suppositories, in addition to find out what analogues it has, and in at the end we learn the opinion of the patients about this drug, who used it for treatment.
Description of the drug
According to the instructions to Klion-D 100, the presented vaginal suppositories are intended for the treatment of mixed infections caused mainly by a yeast-like fungus in combination with trichomonads. The course of treatment, as a rule, is about ten days, after which it is necessary to confirm the absence of a pathogen by means of a control test , which must be performed during the next three menstrual cycles. It is worth noting that this tool has some contraindications for use. For example, these candles can not be used in the first trimester of gestation, and in addition, when breastfeeding.
pharmachologic effect
The antifungal effect of the drug Klion-D 100 is made possible by two powerful components: miconazole and metronidazole. The first active ingredient in vaginal suppositories fights the disease by acting on the cell membranes of pathogenic microorganisms.
These microorganisms begin to weaken and soon die. The substance miconazole helps to get rid of irritating itching, which is often accompanied by fungal ailments.
Candles "Klion-D 100" act as an antiprotozoal and antibacterial agent. The active substances penetrate the DNA of microbes, blocking cell division processes. Due to this, the pathogen stops growing and reproduction.
Since the absorption of this drug is very high, the active components of the drug penetrate into breast milk, spinal cord and placenta. This drug is excreted in the urine. In this regard, urine may be brown.
Composition and format of the issue
According to the instructions, Klion-D 100 is available in the form of vaginal suppositories. Each candle contains 100 milligrams of metronidazole and miconazole. In addition to these components, sodium lauryl sulfate is also used along with magnesium stearate, povidone, colloidal anhydrous silicon and sodium bicarbonate. In addition, crospovidone, tartaric acid and lactose monohydrate are also included.
Vaginal suppositories are white in color and have an almond shape with a rough surface. Candles are packed in ten pieces in foil blisters. The composition of this medicine is aimed at destroying the focus of fungal infection in a short time, and in addition, actively resisting it.
In what cases is the use of Klion-D 100 indicated?
Indications for use
The presented drug is used to treat female infections that arose on the background of infection with Trichomonas and Candida. That is, this medicine is used for thrush and vaginitis of a different nature.
During pregnancy
During lactation and during the first three months of gestation, the use of this drug is strictly contraindicated. This is primarily due to the fact that it can penetrate the placental barrier and into breast milk. Starting from the second trimester, this tool in the form of vaginal suppositories is used only as prescribed by the doctor if there is an emergency.
With menstruation
There is no definitive ban on the use of these vaginal suppositories during menstruation. But during the release of blood mass, some fraction of the dissolved candle may simply come out. In the end, it turns out that, for example, only half the dosage will have an effect, which, of course, is not enough for treatment. In this regard, it is better to postpone the therapy with the presented drug during this period of the cycle, since there will be no effect when using candles.
Contraindications
These vaginal suppositories should be used with caution in women who have an individual intolerance to at least one ingredient that makes up the medicine. The contraindication for vaginal suppositories is also considered the first twelve weeks of pregnancy, and in addition, the lactation period. It is also forbidden to combine this medicine with alcoholic beverages or medical means based on disulfamiram.
Like any other medication, these vaginal suppositories can provoke one or another side effect in patients. Next, we find out what adverse reactions should be feared when they are used for treatment.
Side effects
Some women complain that they have orange discharge after this medication, patients consider them to be an adverse reaction. But in fact, the discharge is completely different depending on the nature of the inflammatory process that occurs in the vagina. Orange color indicates a strong inflammation of the mucous tissue. Such a specific color occurs due to blood impurities from the affected area. This phenomenon is considered normal and does not require instant interruption of vaginal suppository treatment.
Also, according to the instructions and reviews, “Klion-D 100" can cause a number of adverse reactions. For example, agranulocytosis, neutropenia, thrombocytopenia or leukopenia may develop. The immune system can respond with anaphylactic shock. In addition, adverse reactions such as a decrease can be observed. appetite, along with the appearance of mental disorders, hallucinations, confusion and poor mood.
As for the reaction of the nervous system, it can respond with headache, cramps, drowsiness, encephalopathy, dizziness, ataxia, or taste disorder. Short-term visual impairment is possible along with blurry images and a decrease in its sharpness. Sometimes patients experience a violation of color perception, as well as optical neuropathy with neuritis.
The digestive system when taking this medicine may be accompanied by nausea, vomiting, diarrhea, dry mouth, inflammation of the mucosa, stomatitis, or anorexia. In laboratory indicators, darkening of urine can be recorded.
Drug interaction
What else does the instruction for use of Klion-D 100 tell us? This drug can be combined with antibiotics from the sulfanilamide category.
This medicine interacts very badly with disulfiramine-based drugs. Their simultaneous use contributes to confusion.
This drug at times enhances the effect of anticoagulants, because such drugs should be prescribed only by specialists.
Vaginal suppositories "Klion-D 100" can increase the concentration of lithium in the blood. For this reason, it is either necessary to adjust the dosage or reduce it.
Alcohol compatibility
Alcohol with this drug is combined very poorly. Their simultaneous use can provoke the development of hyperemia, abdominal pain, vomiting, nausea, or headache.
Dosage and overdose
Usually, no more than one suppository is used by the intravaginal method. In the presence of any fungal disease, no more than one suppository should be used once.
An overdose of this drug in the form of vaginal suppositories is not possible. But in the event that for any reason it does occur, then poisoning will occur, which will manifest itself as nausea, vomiting, abdominal pain, diarrhea, itching, and in addition, a metallic taste in the mouth. In case of an overdose, ataxia, convulsions or a decrease in white blood cells are not excluded.
Instructions for use
This drug in the form of vaginal suppositories for various genital infections is used, as a rule, in different ways. For example, with trichomoniasis, vulvovaginal candidiasis or thrush, one candle is used intravaginally for ten days in the evenings.
Shelf life of the drug
Presented vaginal suppositories should be stored at a temperature not exceeding thirty degrees. The effect of moisture, as well as sunlight, on this product should be minimal. The described drug from the moment of release can be stored for no more than five years.
special instructions
You can not drink alcohol with a course of therapy with this drug. Even within the next few days after completing the therapeutic course, it is recommended not to drink alcoholic beverages. These vaginal suppositories are forbidden to use longer than ten days and no more than three times a year. Women who are on peritoneal hemodialysis do not need to adjust the dosage of vaginal suppositories.
Discontinuation of the use of this drug is required if there is excessive sensitivity of the genital mucosa, and in addition, against the background of the development of leukopenia. During treatment with vaginal suppositories “Klion-D” it is forbidden to perform the Nelson test, as it will be false positive. Particularly careful with this drug in the form of suppositories, diabetics and patients with impaired microcirculation should be treated.
Cost of medicine
Vaginal suppositories "Klion-D 100" in the amount of ten pieces in one package cost an average of two hundred and ten rubles. The described drug is dispensed only by prescription.
Analogs of Klion-D 100
Absolute analogues of this drug are Neo-Pentoran along with Metromicon-Neo. Among the substitutes with a similar effect include “Geynomaks” along with “Klomegel”, “Wagisept” “Ginalin” and “Wagiferon”.
Women's reviews
Mostly happy reviews are found about Klion-D 100 suppositories. Women especially praise this drug for its help in fighting thrush. It is reported that with bacterial diseases of the female genital organs, this drug very quickly and effectively copes with itching and burning.
In addition, women in reviews of Klion-D 100 write that in bacterial diseases three days after the use of this medicine, the discharge stops. But, unfortunately, there are many complaints of various adverse reactions, such as headache, insomnia and dizziness.
Thus, the presented drug, according to patients, very quickly removes the most unpleasant medical symptoms. Women consider this tool effective and appropriate for the treatment of various bacterial infections.