The health of most people today is quite fragile, as getting the right amount of nutrients from food is becoming increasingly difficult. Therefore, an increasing number of people have to deal with the problem of deficiency of certain vitamins and minerals. As a rule, such conditions lead to serious diseases. For example, the state of iron deficiency sooner or later leads to iron deficiency anemia, which can be dealt with only through prolonged use of specialized drugs.
An effective tool in this case is the drug "Venofer". However, the ability to take this drug does not always exist. Therefore, it would be prudent to investigate which analogues of the drug can be used with equal effectiveness. This article will help you make this choice, in which the instructions for the Venofer tool, reviews and analogues will be examined. It is important to pay attention to this information.
Indications for use of Venofer and its analogues
In order to choose the right method of treatment, it is important to explore the key nuances regarding the drug Venofer. Instructions for use, reviews and analogues of this drug will be considered by us further.
According to the testimony, as well as the method of using the Venofer drug, the following analogues in Russia exist: Ferrum-Lek, Fermed, Dextrafer, Ferinzhekt, as well as Ferrolek-Zdorov. In addition to these, “Argeferr” and “Likferr” are especially popular. All of them have similar properties, methods of use and contraindications, with rare exceptions, to which attention will be paid. Otherwise, everything described below equally applies to the presented analogues of Venofer.
Antianemic drugs are used to correct iron deficiency conditions in the following cases:
- the need to make up for a serious iron deficiency in the body in a short time;
- the patient's inability to take such drugs orally;
- non-compliance by the patient with the treatment regimen for some time;
- the disease is accompanied by serious impaired intestinal function, which does not allow the gland, which is part of oral preparations, to be absorbed.
All of these analogues correspond to this purpose. However, in any case, before replacing the drug, you should get the appropriate advice from a specialist.
The main active substance
The main active ingredient of the drug is iron (III) hydroxide sucrose complex. The analogue of "Venofer", having an identical composition, is called the "Surfer".
Excipients as part of antianemic drugs
Distilled water and sodium hydroxide are additional components that both Venofer and Venofer analogues for intravenous administration contain.
The pharmacological effect of this group of drugs
The drug "Venofer", analogues (in Moscow they can be found without problems) have the following scheme of pharmacological effects on the patient's body. We have already considered that these are preparations containing iron. The chemical composition does not allow the substance to be excreted by the kidneys in the form in which it enters the body. In the human body, drugs are not able to release iron ions, which is why these drug complexes are reasonably considered absolutely stable.
The use of analogues of "Venofer" and dosage
Means "Venofer", analogues administered intravenously, as a rule, are taken according to a similar scheme.
The drug should be administered as slowly as possible using ordinary or drip intravenous injection or using a dialysis system. "Venofer" and analogues of "Venofer" intended for intravenous administration should be administered exclusively intravenously.
Immediately before starting a full-fledged treatment, the original drug or analogue of Venofer must be checked for compatibility: it is necessary to find out if any unwanted reactions from the body occur. For this, a test dose is administered once, which is part of the standard therapeutic dose for this patient. It is imperative to have at hand the means for first aid in case of any side effects. If in the next fifteen minutes no adverse events occur, you can safely enter the rest of the therapeutic dose of the drug.
In order to prevent the drug from getting into the perinovenous space and significantly reduce the risk of arterial hypotension, the drug solution should be administered by drop infusion.
It is not recommended to change the proportions of the drug and physiological saline, so as not to violate the stability of the therapeutic agent.
The maximum tolerated dose is seven micrograms of iron per kilogram of patient weight. The drug should be administered at this dosage for at least three and a half hours, regardless of the total volume of the drug, at most once a week.
You can enter the solution intravenously undiluted, but in this case, you should adhere to some conditions. For example, the rate of administration should not exceed one milliliter per minute. The maximum allowable volume of undiluted solution for a single injection should not exceed ten milliliters.
In the same way, Venofer, analogues of the drug can be administered using the dialysis system. However, only subject to careful observance of the rules for intravenous injection.
If the dose that the patient needs at the moment significantly exceeds the maximum allowable for a single injection, then the drug solution should be administered in parts.
If in the period from seven to fourteen days from the start of treatment there is no improvement in the patient's condition, then it is important to review the diagnosis that was originally established.
For adults, the standard dosage is from five to ten milliliters of Venofer (depending on the weight of the patient). The drug is administered from one to three times a week, depending on the appointment of a specialist.
For children, the drug is administered only if there is an urgent need for a dose not exceeding 0.15 milliliters of the drug per kilogram of the child’s weight. Injections are made from one to three times a week, depending on the condition of the patient.
Features of the application of analogues "Venofer"
Both the Venofer preparation and any of its analogues are recommended to be mixed exclusively with a sterile 0.9% sodium chloride solution. All other solutions intended for intravenous injection, use in this case is strictly prohibited.
It is not recommended to use this tool simultaneously with any other iron-containing preparations, so as not to artificially reduce the absorption of iron by the body. That is why, if the administration of any oral drugs of this group is prescribed, it must be started no earlier than five days after the end of the use of Venofer.
As a rule, the use of Venofer and its analogues in no way affects the patient’s ability to drive a car or work with complex mechanisms. However, if the patient is prone to dizziness and confusion after using this medication, you should refrain from life-threatening actions.
It is important to remember that the drug is strictly prohibited for use during the first trimester of pregnancy, during the main period of fetal formation. Large-scale studies of the effect of Venofer on the body of a pregnant mother and her child have not yet been conducted. However, the limited results that are available at the moment, did not reveal any negative impact on the body of pregnant women.
An intravenous drug does not enter the mother’s breast milk, therefore, it can not harm a newborn in any way.
Despite the prevalence of the Venofer preparation, analogs in tablets are not so easy to find. Yes, and injection solutions are recognized as the most effective.
Adverse Reactions Specific to Venofer Analogs
It is important to remember that the adverse reactions possible with the use of Venofer can equally cause the analog of Venofer, which is identical in composition.
At the moment, it has been found out what undesirable effects can occur in the human body when taking the drug. Despite the fact that the incidence of adverse reactions is not more than one hundredth of a percent, it is not worth ignoring the possible onset of negative consequences. It is recommended to carefully study this item in order to be prepared for the occurrence of side effects of the drug.
Some manifestations occurred in one and a half percent of patients, therefore, were included in the group of the most common adverse reactions to the drug, officially registered. This group included nausea, hypotension, chills, dysgeusia, and pyrexia.
All adverse reactions are classified in accordance with the body system from which they arise. Thus, anaphylactoid reactions can occasionally occur on the part of the immune system .
The nervous system often responds to the Venafer drug, analogues of the drug by distortion of taste sensations, dizziness and an obsessive headache are less likely. Very rarely, patients suffer from fainting, burning of the skin and paresthesia. There is no official confirmation of the following reactions, but their occurrence is regarded as possible: confusion and impaired consciousness.
The cardiovascular system can respond to Venofer and the analogue of Venofer in ampoules by the appearance of a rapid heartbeat, tachycardia, possibly bradycardia, as well as arterial hypotension or hypertension, sometimes circulatory collapse.
Sometimes shortness of breath or even bronchospasm occurs.
The gastrointestinal tract sometimes reacts with diarrhea, severe abdominal pain, nausea and vomiting.
Sometimes there are unpleasant reactions on the skin, such as severe itching, rash, urticaria, erythema and exanthema.
The musculoskeletal system can respond as follows: joint swelling, muscle spasms, arthralgia and myalgia.
The body as a whole can respond with hot flashes, chills, fever, and general discomfort. Local reactions may occur at the injection site, such as burning, pain, inflammation, skin discoloration. Less commonly, fatigue, general malaise, fever, local edema are felt. Sometimes the patient experiences pain in the back, excessive sweating, pallor of the skin.
Chromaturia may occur.
Fersinol is a safe remedy
There are analogues, the action of which does not cause so many adverse reactions. The most popular of them is Fersinol, the use of which is much safer than others. If the occurrence of any side effects is extremely undesirable, the use of this particular drug is recommended.
Conditions for the sale of drugs
All drugs of this group of medicines are dispensed in pharmacies strictly according to the prescription prescribed by the doctor. That is why you should not resort to self-medication and purchase drugs on your own initiative. Any medications that are designed to correct iron deficiency conditions should be taken only as directed by a specialist and under his supervision.
Generalization
General information about the Venofer preparation, instructions for use, analogs and their use are enough to determine whether it is worth taking drugs of this pharmacological group, as well as which ones (Venofer or one of its analogues).
It is important to remember that any means of the antianemic group should be used only after the diagnosis of anemia has been confirmed by specialists and all clinical studies have been conducted. Otherwise, drugs of this class can pose a potential threat to the life of the patient. In no case is it recommended to take the medicine as a preventive measure as self-medication, it can be dangerous to health and life.
Instructions for use will safely help using the Venofer preparation. Analogues of the drug are not absolutely safe and carry the same threat if used improperly, as Venofer itself. That is why a thorough study of the instructions for the drug will guarantee the patient’s full awareness and further safety during treatment. In this case, the antianemic drugs will become a valuable help in the correction of iron deficiency conditions.
Be careful, rely on the authoritative opinion of experienced professionals and never get sick!