In the article we will consider the instruction on the use of Zinnat. The price of the drug is of interest to many.
Antibiotics from the group of cephalosporins are considered very effective, and they are often prescribed for both adults and children with the appearance of infectious diseases. One of the most popular drugs among the group of these drugs is considered to be the Zinnat drug. Unlike many other means of this group, it is not produced by injection.
Drug Information
According to the instructions for use, Zinnat is currently very widely used to treat purulent infections. This drug is used in various fields of medicine, including pediatrics. This medication is characterized by a sufficiently high efficiency and effectiveness. It differs from other similar medicines in low toxicity, which makes it possible to prescribe it to children, starting from the age of three months.
The presented agent belongs to the class of antibiotics, namely to cephalosporins that are resistant to beta-lactamases. Thanks to this, Zinnat is active in the fight against most common strains of pathogenic organisms. “Zinnat” is sold in pharmacies in the form of special soluble granules that are used to prepare the suspension, and this product is also produced in the form of oral tablets.
Forms of drug release
As the instructions for use indicate, “Zinnat” is produced in the following forms:
- In vials (suspension), inside of which 1.25 grams of white granules are contained. The size of the granules is less than three millimeters, and they have an irregular shape. When water is added, a yellow suspension with a fruity odor is obtained. A glass is attached to the bottle so that you can accurately measure the required amount of water, as well as a spoon for dosing the drug. Instructions for use with the Zinnat suspension are in each pack.
- The drug is also released in tablets that are film-coated. The pills are white and have an oval convex shape. These tablets have two dosages: 125 and 250 mg. Instructions for use with Zinnat, which is in each pack, are very detailed. Tablets are sold packaged in ten pieces in blisters. In one pack is one blister.
The composition of the drug
According to the instructions for use in Zinnat for children and adults, cefuroxime serves as the active substance in any form of the drug presented. In 5 milliliters of suspension, this component is contained in an amount of 125 milligrams. One tablet may contain the active ingredient 125 or 250 mg.
Instructions for use with Zinnat tablets confirm this.
Xanthan gum, along with povidone and stearic acid, are additional ingredients in the liquid composition. The sweet taste of the drug is ensured by the presence of aspartame, sucrose and acesulfame potassium in it, and the smell is given by the flavor of Tutti-Frutti.
Auxiliary ingredients of tablets are sodium lauryl sulfate along with hydrogenated oil and colloidal silicon dioxide. The shell is made of parahydroxybenzoate, propylene glycol, white dye and hypromellose.
The principle of the effect of the drug
According to the instructions for use, Zinnat is an antibiotic from the cephalosporin category. He represents their second generation. The presented drug is very active in relation to a large list of pathogenic organisms. It is worth saying that this medicine will be effective if amoxicillin or ampicillin is not affected by microbes. By influencing the formation of walls in bacterial cells, the active substance cefuroxime produces a bactericidal effect.
This medication is active against Escherichia coli, Klebsiella, gonococcus, protea, various types of staphylococcus, many streptococci, borrelia and a number of other microorganisms. But it is worth emphasizing that Zinnat will not help if the cause of the infection is listeria along with enterococci, enterobacteria, pseudomonads, cytobacteria, legionella and some other parasites.
In addition to this medicine, some staphylococci can be very resistant along with clostridia and other microbes that cefuroxime is not effective enough. In this regard, before treatment, it is desirable to determine the sensitivity of the pathogen. We should also not forget that this medicine does not act on viruses. In this regard, in the presence of influenza, mononucleosis, chickenpox and other viral infections, it is not used.
Suitable "Zinnat" for children. Instructions for use are discussed below.
Indications for use of the drug
The drug is prescribed for patients with infectious diseases caused by organisms sensitive to Zinnat. The medication presented is prescribed to patients in a number of the following cases:
- Against the background of the development of otitis media, pharyngitis, sinusitis, tonsillitis or another disease of the upper region of the respiratory system.
- With urethritis, pyelonephritis or cystitis.
- If the patient has furunculosis, pyoderma, or other bacterial infection of the skin.
- With the development of pneumonia or bacterial bronchitis.
- Against the background of gonorrhea or borreliosis.
At what age is it allowed to take the drug?
According to the instructions for use, Zinnat is very effective for treating adult patients, but it can also be prescribed for children. For example, suspensions are used in childhood to treat babies older than three months. But it must be emphasized that the neonatal period is a contraindication to treatment with this drug.
Children from four months to three years of age are prescribed only a liquid form. Tablets are prescribed at the age of three years and older, however, provided that the child can swallow them without biting. In the event that a small patient is more than three years old (for example, six), and he is still protesting against the solid form of the drug, then Zinnat suspension should be used for his treatment.
Instructions for use also contain information on contraindications.
Contraindications
Any form of this medication should not be used to treat patients with intolerance to cephalosporins. The restriction on the use of the suspension is phenylketonuria, since the composition of this form of the drug includes aspartame. In the event that the patient has renal pathologies or diseases of the digestive system, then the presented drug should be prescribed with caution. The presence of sucrose in the liquid form of Zinnat must be considered when using the drug to treat patients with diabetes.
Side effects
Zinnat is able to cause many different side effects in people. Against the background of taking Zinnat, the following negative reactions may occur in patients:
- The occurrence of allergies. Often, such a reaction manifests itself in people with a rash on the skin. In addition, urticaria and itching are not excluded. In more rare cases, fever is possible.
- The appearance of loose stools, nausea, or pain in the abdomen is likely. Sometimes taking this medicine leads to vomiting or colitis.
- Dizziness and headaches are possible.
- As adverse reactions in patients, an increase in the activity of liver enzymes is possible. Sometimes this medicine provokes hepatitis and cholestatic jaundice in people.
- Against the background of treatment with the presented drug, an increase in the number of eosinophils is likely along with a decrease in the level of platelets and white blood cells.
- The development of candidal infection.
The method of taking Zinnat tablets for adults
Usually, Zinnat medicine in tablet format is required to be taken for seven days. But the duration of the treatment course can be from five to ten days. The instructions for the use of Zinnat tablets (250 and 125 mg) recommend taking the drug immediately after eating.
For adults, 250 milligrams of the drug is prescribed twice for the treatment of most infectious diseases. In the treatment of infectious pathologies of the urinary tract, 125 milligrams is also taken twice. In the presence of infectious diseases of the lower respiratory tract, 250 mg are prescribed to patients twice a day. The instructions for use with Zinnat indicate that against a background of severe illnesses, the dosage is increased to 500 milligrams twice. In the presence of uncomplicated forms of gonorrhea, patients are shown a single dose of 1 gram of the drug. For the treatment of Lyme disease, 500 milligrams is prescribed twice, and the course of treatment lasts twenty days.
Instructions for use with Zinnat tablets (250 mg or 125 mg) are best studied in advance.
Suspension for children
For breeding granules, a measuring cup is used. In it, up to the mark of 37 milliliters, boiled non-hot water is collected. After shaking the treatment granules, water flows into them, the bottle closes and turns over. The vial should be shaken vigorously for about fifteen seconds, and then turn over and shake again a little more.
Before use, measure the desired volume of the drug with a dosage spoon. In the event that the child did not like the taste, then the drug is mixed before use with fruit juice or a small amount of milk. But you can not add hot liquid to the suspension.
The drug is prescribed twice after a meal. Dosage for children over two years of age is usually 5 milliliters. It is worth noting that from this amount of suspension the child receives 125 milligrams of cefuroxime. In the event that a small patient has otitis media or there is one or another serious infection, then a single dose increases to 250 milligrams (two tablespoons of suspension). Thus, a child receives 500 milligrams of cefuroxime per day.
Children who are younger than two years old often calculate the dose by weight. A similar definition of a single dosage of the drug is often used for children who are over two years of age. To carry out the calculation, the baby's body weight in kilograms is multiplied by ten, and in severe infections by fifteen. The resulting number indicates the amount of cefuroxime in milligrams that you need to give the child at one time.
What dosage to choose for a child, according to the instructions for use with Zinnat tablets (250 or 125 mg)?
Pills for treating children
In most situations, a single dosage for a child is just one pill, which contains 125 milligrams of cefuroxime. If there is a severe infection, one dose is given at one time, either with doubled dosage or two 125 dosage pills. The instructions for use for Zinnat for children contain this information.
The tablets must be swallowed and washed down with some water. They can not be broken, crushed into powder or cut into several parts. In the event that the child cannot swallow the pill, it is best to abandon this form of medication and prefer treatment with a suspension.
Overdose
According to the instructions for use in the Zinnat suspension for children, if it is drunk in a larger dosage than prescribed by the doctor, this can cause nervous excitement, and in some patients with an overdose, convulsions can also occur. Such negative symptoms are often treated symptomatically, and dialysis is performed against the background of severe conditions. The same applies to tablets.
Interaction with other medicines
It is not recommended to take Zinnat along with drugs that lower the acidity in the stomach, as this can seriously affect the absorption of cefuroxime and its bioavailability. The combination with diuretic drugs can prevent the excretion of the active component of cefuroxime by the kidneys, because of this, its concentration in the plasma will increase significantly. In the event that giving the patient tablets or suspension in parallel with treatment with aminoglycosides, this will have a toxic effect on the kidneys.
This is stated in the instructions for use.
Zinnat's price and storage conditions
To purchase Zinnat granules or pills in pharmacies, you must provide a prescription from a doctor. On average, one bottle containing the granules of the drug costs about 260 rubles, and the cost of one package of tablets of 125 milligrams of cefuroxime costs patients about 240 rubles. 400 rubles is a dosage of 250 mg.
A package with pills and a packed vial with granules are stored in a room protected from children at a temperature not exceeding thirty degrees. The storage temperature of the prepared suspension is, as a rule, up to two degrees, therefore, after dilution, this preparation must be kept in the refrigerator. Shelf life of drug granules is usually about two years, and Zinnat tablets can be stored for three years. As for the suspension, immediately after dilution it can be stored in the refrigerator for about ten days.
This is confirmed by the instructions for use. The price of Zinnat tablets (250 or 125 mg), as well as the suspension of buyers, is not scary. Consider their feedback in more detail.
Reviews about Zinnat
We reviewed the price and instructions for the use of Zinnat 250 for children and adults. What do patients say about this medication?
In most of the comments that describe the treatment with Zinnat, people respond very well to this medicine. Parents who sometimes turn to this medicine to treat their children are also praising the drug. They confirm that the medication presented is very effective in combating such ailments as otitis media, tonsillitis, sinusitis, boils and coughing with bronchitis.
Adult patients also note that the Zinnat medical product effectively copes with various health problems caused by harmful bacteria. This is also confirmed by doctors who admit that they often prescribe Zinnat to their patients.
Parents often choose the Zinnat suspension for children. Instructions for use with it are simple and straightforward. It is noted that this form of the drug is particularly convenient for childhood treatment due to the ease of dosing.
The disadvantages of this drug, consumers attribute the appearance of various side effects. Most often in the comments it is noted that against the background of Zinnatom treatment, patients experience diarrhea or vomiting. And some children complain to parents that they did not like this medicine.
Analogs of Zinnat
The drug “Zinnat” can be completely replaced with other drugs that are made on the basis of cefuroxime. For example, “Aksetin” along with “Zinacef”, “Cefurus” and “Cefurabol” are among such medicines. But it is worth saying that almost all of these drugs are available in the form of powder for injection, which is not very convenient. In the form of tablets, only Axosef, Cetil Lupine and Zinoksimor are available.
Other antibiotics from the category of cephalosporins or penicillins, for example, drugs such as Suprax along with Ospamox, Ecoclave or Augmentin, can serve as a substitute for Zinnat.
Also, based on an analysis of the sensitivity of bacteria, the doctor can replace Zinnat with antibacterial agents in the form of Sumamed, Macropen, Vilprafen and so on. But replacing the drug yourself is unacceptable. Only a doctor should determine which antibiotic is best suited to a particular patient in the presence of a certain infection.
We reviewed the instructions for use with Zinnat tablets and suspensions.