Means "Acetylcysteine" describes the instructions for use as a mucolytic medicine. The medication helps to increase the volume and dilute sputum, facilitate its excretion from the bronchi. The activity of the drug is associated with the properties of sulfhydryl groups. They are able to break disulfide bonds in acid mucopolysaccharides of sputum. This provokes the depolarization of mucoproteins and a decrease in the viscosity of mucus. The medicine “Acetylcysteine” (instructions for use contains such information) has an antioxidant property due to the presence of the SH group, which interacts and neutralizes oxidative electrophilic toxins. The tool enhances the synthesis of glutathione - an important antioxidant element in intracellular protection, ensuring the maintenance of functioning and morphological cellular integrity. After penetration into the bloodstream, the drug binds to plasma proteins by 50%. The medicine passes through the placental barrier, is present in the amniotic fluid. A small amount of the drug goes through the intestines.
Prescribing Acetylcysteine ​​Medication
Drugs with a mucolytic effect are prescribed for respiratory pathologies and conditions complicated by the production of viscous, mucopurulent sputum difficult to separate. Therapy is recommended for chronic and acute bronchitis, tracheitis due to a viral or bacterial infection, bronchiectasis, pneumonia. Instructions for use include atelectasis (as a result of clogging in the bronchi), bronchial asthma to the indications for using the “Acetylcysteine” agent. As part of the complex effect, the drug is recommended for cystic fibrosis. The medicine is indicated after injuries and operations to remove mucus from the bronchi, as well as to improve sputum secretion in sinusitis.
Dosage regimen
The medication "Acetylcysteine" is intended for inhalation. Dosage - 2-5 ml of a twenty percent solution three to four times a day. The duration of the procedure is 15-20 minutes.
Means "Acetylcysteine." Instructions for use. Adverse reactions
Typically, drug tolerance is satisfactory. Rarely, nausea occurs (usually due to the specific smell of the drug), local irritation in the respiratory tract, and reflex cough. Some patients may have rhinitis, stomatitis.
The medicine "Acetylcysteine." Instructions for use. Contraindications
Do not prescribe medication for exacerbations of duodenal ulcers or stomach, pulmonary hemorrhage, hemoptysis, hypersensitivity, bronchial asthma without thickening of sputum. The advisability of conducting therapy in the prenatal period and during lactation is determined by a specialist.
additional information
When working with the medicine, it is recommended to use glass vessels, to avoid contact of the product with rubber or metals in order to avoid the formation of sulfides with a specific odor.