Drotaverinum is an effective antispasmodic of myotropic and vasodilating action. The main active ingredient of the drug is drotaverine hydrochloride. In its pharmacological actions, the drug is similar to papaverine, but has a more pronounced therapeutic effect.
The composition of the drug "Drotaverin"
Drotaverine hydrochloride is the main component of this medication, each tablet contains 40 mg of this substance. Auxiliary components include:
- lactose;
- potato starch;
- povidone;
- talc;
- magnesium sterat.
Drotaverine is also produced as an injection solution. In this case, the amount of drotaverine hydrochloride in each ampoule is 20 mg.
The injection solution is available in the form of ampoules, each of which includes 20 ml of the main substance. In the form of tablets yellow with a greenish tint - each tablet contains 40 mg of drotaverine hydrochloride.
What are the indications for taking Drotaverinum?
What is Drotaverin? What are these pills from? The tool is aimed at reducing the smooth muscle tone of many internal organs and weakening the intestinal motility. It is able to dilate blood vessels. Often, a medicine is prescribed to eliminate spasmodic syndrome. Although the medication does not apply to pain medication, it acts on the cause of the pain.
So, such diseases and conditions may become indications for the use of the drug "Drotaverin":
- Exacerbation of gastric ulcer and 12 duodenal ulcer.
- Pylorospasm.
- Intestinal colic, proctitis.
- Spastic colitis, constipation, tenesmus.
- Soreness in spasms of the vessels of the head, coronary arteries, endarteritis.
- Pyelitis.
- Biliary dyskinesia.
- Biliary and renal colic.
- Cholecystitis.
- The threat of miscarriage or the onset of premature birth.
- If the opening of the uterus is delayed during childbirth, as well as during postpartum contractions.
- The medicine is prescribed during preparation for various procedures, for example, when installing a catheter in the ureters, or with cholecystography.
- As part of complex therapy for diseases of the gastrointestinal tract.
- Menses with severe pain.
In addition, sometimes a headache of a spastic nature can be relieved with Drotaverinum.
If the tablet form is prohibited for any reason, then you can use the medicine in the form of a solution.
It is prescribed to eliminate spasms of smooth muscles:
- In the urinary system. For example, with nephrolithiasis, urethrolithiasis, pyelitis, cystitis, tenesmus of the bladder.
- With diseases of the biliary tract. These include cholecystolithiasis, cholangiolithiasis, pericholecystitis, cholangitis, papillitis.
Thus, we can conclude that the medicine can be used for symptomatic treatment, when the main symptom of the disease is pain, during some medical procedures and procedures, in gynecology and even for preventive purposes with the threat of the development of some diseases. The scope of the drug is extensive.
Contraindications
Contraindications include the following:
- Individual intolerance to one or more components of the drug.
- Severe renal and hepatic insufficiency.
- Reduced cardiac output and development as a result of severe heart failure.
- Age up to 1 year.
- Glaucoma.
In which cases the medicine should be prescribed with caution
With the following pathologies and conditions, Drotaverinum is prescribed with caution:
- BPH;
- atherosclerosis of the coronary arteries in severe form;
- hypotension;
- angle-closure glaucoma;
- prostatic hyperplasia.
You will also need additional consultation with a doctor regarding taking Drotaverinum during pregnancy.
Side effects
Side effects of Drotaverin, subject to all the rules for taking the drug, are extremely rare. Usually the patient undergoes a course of therapy without complications.
Such side effects from Drotaverinum rarely develop:
- Nausea and vomiting, constipation.
- Pain in the head of dizziness.
- Sleep problems, palpitations.
- Very rarely hypotension develops
- Quincke's edema also occurs in rare critical cases.
Some patients report side effects after taking Drotaverinum:
- feeling of heat;
- sweating
- skin rashes;
- swelling in the nose.
Overdose
In case of drug overdose, the following side effects of Drotaverin may occur:
- AV block.
- Cardiac muscle arrest.
- Respiratory paralysis.
Rules for taking tablets and solution
You need to take the tablets inside, while drinking them with water. It is forbidden to chew or grind the medicine before taking. An exception may be children who cannot swallow a whole pill. In this case, you can grind the medicine into powder and dilute in a small amount of water.
The instructions do not indicate when to take the product - before or after a meal. But many doctors recommend drinking the medicine after meals. If the meal was carried out a long time ago, then before you drink the Drotaverin tablet you can eat an apple, a banana, a small sandwich, etc. That is, there may be little food, the main thing is that the medicine should not be taken on an empty stomach.
The duration of the therapeutic course is determined by the attending physician.
The dosage of "Drotaverin" for adults is as follows: 1-2 tablets three times a day, while the maximum dose per day should not be higher than 240 mg.
For children:
- From 3 to 6 years - 40-120 mg, which are divided into 2-3 doses. A maximum of 120 mg can be taken per day, dividing this dose into several doses.
- From 6 to 12 years - 2-5 tablets, which are also divided into several doses per day. The maximum dose per day is no more than 200 mg.
If we talk about the solution, then it is administered subcutaneously or intramuscularly at 40-80 mg from one to three times a day. At each dose, 2-4 ml of the drug is administered.
Special instructions are available to prevent renal or hepatic colic. In this case, the solution must be administered slowly, 40-80 mg intravenously.
All the above treatment regimens are considered conditional and stereotyped. Only a doctor can determine at what dose the medicine is indicated to the patient, depending on the particular case.
Analogs
There are analogues and substitutes for Drotaverinum, which may be similar in composition or effect. The following are drugs with a similar effect, "Drotaverinum":
- "Platifillin with papaverine."
- "Papaverine hydrochloride MS."
- "Band".
There are also synonymous drugs "Drotaverina" with the same chemical composition:
- Spazmol;
- "Bioshpa";
- Nosh Bra;
- Vero-Drotaverin;
- "Spakovin";
- No-shpa;
- Droverin;
- Ple Spa.
Special instructions for use
When the solution is injected inside so that collapse does not develop, the patient should be in a horizontal position. During the use of the drug, especially in the form of a solution, people should limit their activity within 1 hour after drug administration. This applies to potentially dangerous actions that require concentration, quick psychomotor actions, etc.
During the treatment of gastric and duodenal ulcers, Drotaverinum is combined with anti-ulcer medication.
In addition, while taking the drug as part of complex therapy, you need to know about the compatibility of Drotaverin with other drugs. If the patient is administered Phenobarbital and Drotaverin at the same time, the antispasmodic effect of Drotaverin will increase.
In addition, the drug has the following effect in some situations:
- The antiparkinsonian effect of levodopa is becoming weaker.
- The spasmogenic activity of morphine under the influence of Drotaverin decreases.
- Increases the effect of bendazole and other antispasmodics.
Under what conditions to store Drotaverinum
You can buy Drotaverin in a pharmacy without a doctor’s prescription. Tablets are stored for three years from the date of manufacture, injection for two years. The place to store the medicine should be dry and dark, and also inaccessible to small children. Storage temperature should not exceed + 25 ° .
As soon as the shelf life indicated on the packaging expires, Drotaverin should be disposed of.
Finally
When purchasing any medicine, be sure to read the annotation to it. But it is impossible to act only according to instructions. The doctor should prescribe the drug, as well as indicate the dosage of the drug and the duration of treatment. Self-medication can lead to dangerous consequences.
Now you know what Drotaverin is and what these pills come from. The medicine really helps, judging by the reviews of patients. It can be used both in the form of monotherapy, and as part of a comprehensive treatment, but in any case only as directed by a doctor.