"Furamag" refers to derivatives of nitrofuran antimicrobial agents. One capsule of the drug contains 50 mg of the active substance furazidine and excipients, talc potassium carbonate and magnesium carbonate.
Pharmacology
The drug "Furamag" is an antibiotic , it is very resistant to gastric acidic environment, has high bioavailability, while the color of urine does not change , its high concentration is observed in the kidneys. Based on the composition of the drug "Furamag", the instruction refers it to complex means, it consists of furazidine and magnesium carbonate in a ratio of 1: 1, the presence of the latter affects its pharmacological properties.
Furamag acts as a highly effective anti-infective agent. The fact of its high concentration in the lymph matters, this creates an obstacle to the transmission of infection through the lymphatic tract. Instructions also indicate high concentrations of Furamag in bile, in slightly lesser amounts - in blood serum, in the liver, in the portal vein. Repeated use of the drug does not cause resistance in microorganisms.
The main principle of the drug "Furamag" is its ability to inhibit nucleic acids. The drug starts in the cell of the microorganism such irreversible processes that inevitably lead to its death. "Furamag" reduces the toxicity of certain microorganisms, this is important, because even before its action leads to their death, an improvement in the patient's condition is observed.
The drug “Furamag” has a wide range of action, it is highly active against many grams of positive and negative bacteria, even those that remain resistant to other antibiotic drugs. Due to this property, the drug "Furamag" instruction recommends its use. Even if it was not possible to achieve high efficiency from other antibacterial drugs.
To the many advantages of the Furamag preparation, the instruction adds its beneficial effect on the immune system (unlike other antibiotics that suppress it). The maximum concentration of the drug in the blood lasts for 8 hours, after 4 hours you can detect the presence of the active substance in the urine, the medicine is excreted by the kidneys, there are recommendations for taking after meals, because then the bioavailability of the Furamag agent increases.
Judging by the pharmacodynamics, one can say about the medical indications of the Furamag preparation, first of all, of course, these are severe inflammatory infections caused by microorganisms that are sensitive to this antibiotic. High efficiency is observed in the treatment of diseases of the genitourinary system, the Furamag remedy is indispensable for cystitis (chronic or acute), urethritis, pyelonephritis.
The instruction considers the absence of side effects among the advantages of the Furamag drug , unlike other nitrofurans, only in isolated cases can nausea with vomiting, neuritis and allergic reactions occur.
Contraindications for taking the drug include the special sensitivity of the body to its components, the pregnancy of the patient and the period of breastfeeding. Treatment with Furamag in renal failure is not recommended.
If an overdose of the drug occurs, it manifests itself in the form of neurotoxic reactions (it is extremely rare and only in patients with diseased kidneys). In these cases, enterosorbent therapy, gastric lavage, and heavy drinking are recommended.
There are a number of drugs, the interaction with which is contraindicated for a number of reasons. These include Chloramphenicol, Ristomycin, sulfonamides (inhibit hematopoiesis), nalidixic acid (causes antagonism). The drug weakens the effect of other uroantiseptics when used together; acid intake is not recommended.
Storage of the drug "Furamag" is recommended in a dark, cool place at a maximum temperature of 25 ° C.