Persistent or transient disorders of blood microcirculation in a particular organ occur throughout the life of each person. Doctors use pharmacological therapy to adjust tissue and organ blood supply. One of the most effective and often prescribed drugs to improve peripheral circulation is Trental.
The medication belongs to the group of vasodilating drugs that improve microcirculation. Influencing two pathological processes at once, which lead to obstruction of blood flow through small vessels, arterioles, hemocapillaries, venules, Trental perfectly helps patients with a large list of diseases. To find out the compatibility of Trental with alcohol and what results from their combined use should be expected, it is necessary to understand in detail how they interact with each other. This question excites many people. Can Trental and alcohol be combined?
Act
The active component of the drug is pentoxifylline. The range of effects of a drug that improves microcirculation is to change the properties of blood under its influence.
The active substance acts on the membrane of red blood cells and on the process of formation of a non-globular protein formed from fibrinogen. The active component increases the elasticity of red blood cell membranes, with the help of which they are better compressed in small vessels. Pentoxifylline eliminates platelet adhesion, which slows down intravascular coagulation. As a result, the active component of the drug reduces blood density.
When using Trental, a decrease in the level of fibrinogen is found in human plasma. Pentoxifylline also increases the effects of fibrinolysis enzymes, which speeds up the absorption of blood clots. With the help of these properties, the medication has a fibrinolytic and anticoagulant effect.
Trental tablets for oral use are well absorbed in the digestive organs, reaching maximum blood levels one hour after use. After entering the bloodstream, the active component is metabolized in the liver.
Metabolites are excreted in urine. The half-life is about two hours. Accordingly, any violations of the kidneys lead to an increase in the content of pentoxifylline in the blood. The use of the next dosage of the drug is fraught with poisoning.
Indications
With the help of a wide spectrum of action, the medication is indicated for administration in the following conditions and diseases:
- Violations of the microcirculation of the brain.
- Discirculatory lesions of brain cells, which is caused by the action of damaging factors, and leads to disruption of the brain structures.
- Raynaud's disease - a violation of the arterial blood supply to the hands or feet.
- Angioneuropathy is a violation of the tone of the capillaries, as a result of which the vascular wall undergoes a change and its full functioning is impaired.
- Frostbite - damage to body tissues under the influence of low temperatures.
- Bronchial asthma is an inflammation of the respiratory system involving a variety of cellular elements.
- Obstructive bronchitis is an inflammatory disease that affects the bronchi and is complicated by obstruction.
How to use the drug?
The medicine in tablets is recommended for use in the amount of three to four capsules up to three times. Trental must be taken after meals. The duration of therapy is set by a medical professional and can be several months.
"Trental" is prohibited for use with increased sensitivity to pentoxifylline or other substances of the drug, as well as a tendency to bleeding. It is not recommended to prescribe the drug to women in the "position" and during lactation.
Can Trental be combined with alcohol?
The study of the interaction of ethyl alcohol, which is contained in alcoholic beverages, with the active components of drugs, as a rule, is not included in clinical trials of drugs. Therefore, the combination of Trental and alcohol has not been investigated either, and therefore there is no information on their compatibility.
Of great importance is also the sequence in which the person who took Trental used alcohol. If the drug was first drunk, and then almost immediately alcohol, then a person may have side effects in the form of bleeding.
The interaction of Trental and alcohol largely depends on what was the interval between their use. To find out how long after the alcohol has been taken, you can use the drug, you need to pay attention to the half-life of the active substance of the drug in the instructions for use.
This is due to the fact that the active substance lowers blood viscosity, and ethanol immediately after it enters the body has a similar effect, enhancing the blood-thinning effect of Trental. When taking the drug, each used dose of a strong drink decreases blood viscosity more and more. This interaction is especially dangerous for people who have had hemorrhages in the brain or retina.
Trental can be combined with alcohol. Since ethanol and the active ingredient of the drug interact in a very different way, if the latter was taken after drinking strong drinks. If you take "Trental" a couple of hours after taking alcohol, it can eliminate the symptoms of a hangover.
Conclusion
Medicines and alcohol are incompatible things. Do not take alcohol during treatment. In order to get a positive effect from therapy, the patient should choose one thing. The most correct decision for a patient who takes Trental for a long time is to completely abandon alcohol during treatment.