The drug "Palin" is available in the form of capsules, suppositories (suppositories) of vaginal tablets. The active ingredient is pipemidic acid.
The drug "Palin" refers the instruction to the uroantiseptics of the quinol series. The drug has a bactericidal effect. The medication is active against most gram-negative microorganisms (including Pseudomonas aeruginosa and Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella). In addition, the drug affects some gram-positive microbes (Staphylococcus aureus, in particular).
Vaginal suppositories do not show activity against infections caused by trichomonads, Candida fungi, chlamydia and mycoplasmas.
The active component of the tablets has good absorption in the digestive tract. Unchanged, it is almost completely excreted by the kidneys. A high concentration of the drug is formed in the urine. The effectiveness of the drug does not depend on the pH of urine.
The drug "Palin". Instruction Indications.
The drug "Palin" is prescribed for chronic and acute infectious and inflammatory diseases, the causative agents of which are microorganisms sensitive to the active component. Among the indications for the drug are the following pathologies: pyelonephritis, prostatitis, urethritis, cystitis.
The drug "Palin". Instruction Contraindications
No medication is prescribed for severe violations of renal, hepatic function, hypersensitivity to pipemidic acid. Contraindication is children's age.
During the therapeutic course, ultraviolet irradiation should be avoided due to the high probability of the development of photosensitization. It is recommended to increase the amount of fluid consumed.
The drug "Palin". Instructions for use.
The average adult dosage is 400 mg (tablet or two capsules) twice a day for ten days. Treatment of infections provoked by staphylococcus involves an interval between doses of no more than eight hours. Therapy lasts, usually ten days. If necessary, the doctor can extend the treatment.
Therapy of acute infectious diseases in the female urinary tract may include the use of both oral and vaginal forms of the drug in combination. As a rule, one suppository is prescribed at night for seven or ten days.
The drug "Palin". Instruction Adverse Reactions
Rash, diarrhea, vomiting, nausea, abdominal pain, and appetite disorder may be noted as undesirable manifestations. In some cases, vision is impaired, headache, mood swings, insomnia develop. In rare cases, hallucinations, impaired consciousness, convulsions were noted. In case of detected metabolic disorders, anemia may occur. When taking the drug, platelet count may decrease, the tendency to bleeding may increase.
When taking the drug "Palin", the reviews of experts are mostly positive. At the same time, doctors do not recommend using the drug during pregnancy. In extreme cases, the drug "Palin" is prescribed in the second trimester. Due to the poorly understood effect of the drug on the health of the mother and fetus, as well as the likelihood of side effects, the drug is considered contraindicated in pregnant and lactating women. This is especially true of the third trimester. During this period, the risk of developing changes in the peripheral and central nervous system increases. The drug "Palin" is able to reduce platelet count. If their concentration at delivery does not recover, the risk of bleeding will increase.
If a urinary tract infection occurs during pregnancy, consult a doctor. The specialist will choose a safer drug.
Before using the drug "Palin", you should carefully study the instructions and consult a doctor.