Macropen are tablets that are coated with a white film coating. In shape they are round, biconvex. Judging by the instructions and reviews, "Macropen" belongs to the antibiotics of the macrolide group. It is prescribed for infectious and inflammatory diseases that were caused by pathogens.
Description
According to reviews, "Macropen" is a good drug to cope with acute infection. After taking the medicine, it is rapidly absorbed in the gastrointestinal tract. A high concentration of the active substance, midecamycin, is observed in the lung tissue and skin. The active substance binds to proteins. The drug is metabolized in the liver. It is excreted in the bile and urine. If you take Macropen for a long time (reviews confirm this), then the growth of bacteria will increase, that is, they will be resistant to the antimicrobial properties of the drug.
The medicine can cause severe diarrhea and dehydration. It is important to use Macropen in patients with a diseased liver with caution in this case. If the person taking the medicine has an allergy to excipients, then it is better to cancel the drug, otherwise bronchospasms can be provoked.
Indications
The use of "Macropen" (in the reviews it is said) is possible if the attending physician recommended this drug. The main indications include inflammation, infections that were caused by pathogenic microorganisms. It is also prescribed for:
- tonsillopharyngitis;
- chronic bronchitis;
- pneumonia;
- acute otitis media;
- sinusitis;
- infections of the skin;
- subcutaneous tissue infections;
- enteritis;
- diphtheria;
- whooping cough;
- diseases of the genitourinary system caused by bacteria.
If the doctor prescribes this drug, then you must strictly follow the instructions.
Instruction manual
If you read the reviews, Macropen should be taken before meals, this applies to the suspension and tablets. Older children and adults are prescribed one tablet per day, but it all depends on the patient’s weight and diagnosis. Children who weigh less than thirty kilograms per day are prescribed from 20 to 40 mg / kg three times, if the infection is severe, then 50 mg / kg three times a day.
The suspension is recommended to be taken twice a day at 50 mg / kg. For children, "Macropen" (reviews - below) is not contraindicated. It is prescribed from 2 months of life. The duration of treatment with this drug is from seven to fourteen days. For prophylactic purposes, diphtheria medication should be taken at 50 mg per day. This dosage should be divided into two. The course of treatment is one week. To prepare the suspension, you need to add 100 ml of boiled water to the contents of the vial and shake. Shake well before use.
Structure
In reviews of "Macropen" it is said that taking pills is easy, since they are available in a convenient form. Sold in blisters of 8 pieces, in cardboard packs. The tablets consist of potassium polacryline, magnesium stearate, talc, microcrystalline cellulose. Granules for suspension are small, orange in color with a banana smell. When the suspension is prepared, it turns orange.
The granules consist of methyl parahydroxybenzoate, citric acid, flavor, hypromellose, sodium saccharinate, mannitol, silicone antifoam, dye. Sold in dark bottles.
Contraindications and side effects
In which cases do not recommend Macropen? The main contraindications include severe liver failure, hypersensitivity to the active substance and auxiliary components, children under three years of age (this applies to tablets). Caution should be taken "Macropen" during pregnancy, breastfeeding, if there is an allergy to acetylsalicylic acid. Pregnant women are sometimes prescribed this antimicrobial if the benefits to the mother outweigh the risks.
During breastfeeding, you should stop taking the medicine. If we talk about an overdose of the drug, then information about severe intoxication is not recorded. With caution, you need to take a suspension of "Macropen" (expert reviews confirm this) and tablets at the same time as alkaloids, carbamazepine, anticoagulants, cyclosporine. Side effects include stomatitis, decreased appetite, vomiting, diarrhea, jaundice, and weakness in the body.
Analogs
At Macropen (from the reviews you can also find out about this), there are two direct analogs that completely coincide in the mode of action and composition: Midepin and Midecamycin. However, these two drugs are rarely available. Macropen is advised to be replaced with generics from the macrolide antibiotic group. Their classification depends on the chemical structure. So, distinguish between natural and semi-synthetic antibiotics.
Erythromycin and Oleandomycin are among the first generation of macrolides. Semi-synthetic antibiotics are Dirithromycin, Roxithromycin, Flurithromycin, Clarithromycin. The second generation includes natural antimicrobial agents that have an excellent molecular structure. These are Spiramycin, Midecamycin, Josamycin, Linkomycin.
Semi-synthetic macrolides are Roquitamycin. All generic counterparts have a lower price than Macropen. You can replace it with Aziklar, Zetamax, Starket, Fromilid, Klafar, Azivok, Azimed and many others.
Reviews
"Macropen" is recommended by approximately 80% of patients who took it, and also left reviews about the drug. It really helps with infections caused by bacteria, after which a cough quickly passes. The advantages include users price, the absence of side effects, quick action, a wide range of effects. "Macropen" helps with sinusitis.
Among the shortcomings: sometimes it causes constipation, negatively affects the gastrointestinal tract, also causes diarrhea, severe dysbiosis. The downside is that it is an antibiotic. As patients note, the number of tablets in the package does not correspond to what is needed for the course of treatment. There is a high probability of side effects. Someone did not notice the result of therapy, there was a pain in the stomach, an allergic reaction. The price of the drug may seem overpriced. Pills cost 276 rubles, and a suspension - 360 rubles.
Doctors say that Macropen is a good and effective drug that can deal with infections instantly. Of course, it cannot be assigned on its own. Only after consultation with a specialist and analyzes can we talk about whether there is a point in the therapy with Macropen. He has a large list of contraindications and possible side effects that occur in highly sensitive people. If the state of health worsens after the medication, then the attending physician should be told about this so that he reduces the dosage or completely cancels the tablets or suspension. Watching young children while taking the drug is especially important carefully.