In the article, we will review the reviews and instructions for Pantocalcin for children and adults.
A drug is a nootropic drug whose spectrum of activity is associated with the presence of GABA in the structure. The pharmacological properties of this medication are due to the direct effect of pantocalcin on the GABAB receptor channel complexes.
Description
The drug has a neurometabolic, neuroprotective and neurotrophic effect, increases the brain's resistance to oxygen deficiency and the effects of various toxic substances, normalizes the anabolic process in neurons, has an anticonvulsant effect, reduces motor excitability with ordering behavior, stimulates physical and mental performance, and helps stabilize the content of GABA in alcohol chronic intoxication and the abolition of ethanol.
The medication also exhibits a pronounced analgesic effect. It is able to inhibit the acetylation reaction, which is involved in the inactivation of novocaine (procaine) and sulfonamides, as a result of which a prolonged action of these substances is achieved. It causes a slowdown in the pathologically high tone of the detrusor and cystic reflex. Reviews about "Pantocalcin" are abundant.
The composition of the drug
This medication contains calcium hopantenate (hopantenic acid or the calcium salt of this acid). As auxiliary elements in the manufacture of the medicine, magnesium hydroxycarbonate, calcium stearate, talc, potato starch are used.
Pharmacokinetics
The drug is rapidly absorbed from the digestive tract. Maximum concentrations are observed in the liver, in the wall of the stomach, kidneys and skin. The active substances of this medication are able to penetrate the blood-brain barrier. It is not metabolized and excreted within 48 hours unchanged.
Reviews on the use of "Pantocalcin" are mostly positive.
Indications for use
A remedy is prescribed for the following disorders and pathologies:
- cognitive impairment in organic brain damage and a variety of neurotic disorders;
- with the complex treatment of cerebrovascular insufficiency, which is provoked by atherosclerotic changes in the vessels of the brain;
- with the initial form of senile dementia;
- organic residual brain damage in elderly patients;
- organic cerebral insufficiency in patients with schizophrenia (in combination with antidepressants and antipsychotics);
- extrapyramidal hyperkinesis in individuals with hereditary pathologies of the nervous system (including Huntington's chorea, Parkinson's disease);
- consequences of traumatic brain injuries and neuroinfections (with complex treatment);
- to correct the side effects of antipsychotics and for prophylactic purposes as "cover therapy";
- epilepsy with inhibition of mental processes (in combination with anticonvulsant drugs);
- neuroleptic extrapyramidal syndrome (akinetic and hyperkinetic);
- psycho-emotional stress, lowering physical and mental indicators;
- to normalize the process of memorization and improve concentration;
- urination disorders: daytime urinary incontinence, enuresis, pollakiuria;
- with mental retardation in children (delayed speech, mental, motor development), cerebral palsy, stuttering (in clonic form), epilepsy (with combined treatment with anticonvulsant medications, especially with the appearance of polymorphic seizures and minor epileptic seizures).
This is confirmed by the instructions for use. Komarovsky’s reviews of Pantokaltsin for children will be presented below.
Release form and dosage
The drug is available in tablets of 250 mg and 500 mg of the active element. The medication is administered orally, after eating after 15-30 minutes. A single dosage for children is 0.25-0.5 g, for adults - 0.5-1 g. The duration of the course of therapy is from one to four months. As for the treatment of specific pathological conditions, the dosage and duration of treatment is prescribed exclusively by a specialist, taking into account the patient's age, type and stage of the disease and other circumstances.
Contraindications
The tool can not be used in the presence of the following pathologies and physiological conditions:
- acute liver failure;
- pregnancy in the first trimester;
- high sensitivity to the substances of this drug.
According to adult reviews, Pantocalcin is generally well tolerated, but dosage must be observed.
Drug interaction
A medication prolongs the effect of barbiturates, increases the effectiveness of drugs that stimulate the central nervous system, as well as anticonvulsants and local anesthetics (novocaine), and prevents adverse reactions from the use of phenobarbital, antipsychotics (antipsychotics) carbamazepine. The effects of hopantenic acid are increased in combination with xidiphone and glycine.
Drug Analogs
Analogues of Pantokalcin medicine can conditionally be divided into two main varieties - preparations that contain the same active substance - hopantenic acid. Similar in this case are drugs that have similar therapeutic activity, but contain other active ingredients.
According to reviews, analogues of Pantocalcin act no worse.
Synonyms of the drug are the following drugs:
- "Gopantam" - in tablets;
- "Calcium hopantenate" - in tablets;
- Pantogam - in the form of syrups and tablets.
Analogs are:
- "Amilonosar" - in the form of tablets and solutions for injection;
- "Acefen" - in tablets;
- "Vinpotropil" - in the form of capsules, tablets and concentrates for solution;
- "Vinpocetine Forte" - in tablets;
- "Ginkoum" - in capsules;
- “Glycine” - in the form of sublingual and cheek pills;
- "Demanol" - solutions for oral prem;
- "Idebenone" in capsules and tablets;
- "Carnitex" - in the form of capsules;
- "Combitropil" in capsules;
- "Cortexin" in the form of a lyophilisate for injection solutions;
- “Lucetam” - in solutions for injections and tablets;
- "Neupilept" - in the form of injection solutions;
- "Neuromet" - in capsules;
- "Noclerin" - oral solutions;
- "Omaron" - in tablets;
- Pantogam - in the form of syrups and tablets;
- "Picanoyl" - in tablets;
- "Pineamine" - lyophilisates for injection solutions;
- "Piracezin" - in capsules;
- "Pyriditol" - in tablets;
- "Semax" - in the form of nasal drops;
- "Celestab" - in capsules;
- "Cellex" in the form of a solution for administration under the skin;
- Epithalamin - in the form of powders for injection solutions.
Consider the instructions for use for "Pantocalcin" for children and reviews.
Use in childhood
The drug is prescribed to children very often. This nootropic drug, which has cerebroprotective, anticonvulsant and antidysuric effects, improves metabolism in cells and tissues, prevents the development of oxygen starvation of the brain, has a mild sedative effect, reduces the incidence of spontaneous motor activity, and reduces hyperactivity in children. Hopantenic acid, which is part of the medication, has an anticonvulsant effect by optimizing the conductivity of nerve impulses and reducing psychomotor excitability.
According to reviews, "Pantocalcin" for children is ideal.
In what cases is appointed?
For children, this drug is prescribed for the following pathologies:
- cognitive impairment resulting from organic brain damage and neurotic disorders;
- with organic cerebral insufficiency during schizophrenia;
- with the consequences of brain injuries and various neuroinfections;
- with extrapyramidal hyperkinesis with hereditary pathologies of the nervous system (for example, hepatocerebral dystrophy);
- with epilepsy, which entails a slowdown in the mental process;
- with disorders of urination.
Adverse reactions
According to reviews of Pantocalcin, during treatment, various allergic reactions in the form of rhinitis, conjunctivitis and skin rashes can occur as side reactions. With the development of such symptoms, the medication should be discontinued. In addition, in some cases, the medicine can cause the appearance of noise in the head, sleep disturbances, and drowsiness.
This is confirmed by the reviews to Pantokaltsin and the instructions.
Such side effects are temporary, and, as a rule, pass quickly, without requiring discontinuation of the drug. There are isolated cases of the development of acute hepatic encephalopathy with a fatal outcome due to a lack of pantothenic acid in the body (vitamin B5).
What else does the instruction for Pantocalcin tell us? Reviews will be presented at the end of the article.
Use during pregnancy and lactation
In the course of scientific tests on animals, it was found that the medication Pantocalcin does not cause an embryotoxic and teratogenic effect. However, due to the fact that such studies have not been conducted in humans, it is impossible to say unequivocally whether this medication is safe during pregnancy. Therefore, the medication is absolutely forbidden for prescription in the first trimester of pregnancy (up to the 13th week inclusive), and in the second and third trimesters it can be used in cases where the expected effect exceeds all possible risks.
It is also not known whether the drug Pantocalcin penetrates into breast milk, therefore, during lactation, one should refrain from using this medication. If for any reason it is necessary to take it, then you need to stop breastfeeding and transfer the baby to an artificial milk mixture.
When driving cars or other dangerous machinery, some caution should be exercised at the beginning of treatment, due to transient side effects, such as drowsiness, tinnitus, etc.
Reviews about "Pantocalcin"
This drug is relatively recently produced by pharmacological companies, so there are not many reviews about its use. Basically, patients who were prescribed this medication suffered from minor impaired memory, attention, impaired mental activity and decreased performance.
According to reviews of Pantocalcin (0.25), a good efficacy of the drug is observed.
It is difficult for people to say for sure whether this remedy helped them or not, since the symptoms of such diseases are very similar to the signs of usual chronic fatigue. And also due to the fact that the medication Pantocalcin is used, as a rule, in combination therapy with other medicines.
We also consider adult reviews of Pantocalcin for children.
Reviews on the use of children
The drug at the present stage of development of clinical medicine is widely prescribed for children with minor mental retardation, poor performance, distraction and impaired concentration. Experts say that the drug is very effective in the treatment of such disorders, however, children should be prescribed it with great care and at the same time with some sedative medications.
Adult reviews of Pantocalcin are most often positive.
Parents of children who were prescribed such treatment observed that the effect was good, the children became calmer, their sleep normalized, their behavior improved.
Reviews about "Pantocalcin" do not end there.
Regarding the side effects caused by this medication, approximately the same negative reactions of the body to its use were observed in both children and adults. Among them, reactions such as nausea, dizziness, and stool disorder most often occurred. Many patients complained of excessive drowsiness during treatment with the drug, which significantly complicated their usual lifestyle.
There are a lot of reviews about Pantocalcin for children.
In some cases, the kids showed manifestations of inhibition, which was very dissatisfying with the parents, since this phenomenon also negatively affected the learning and behavior of children. Adverse symptoms from the use of the medicinal product disappeared in most cases after discontinuation of the drug or adjustment of therapeutic dosages.
We reviewed the reviews and instructions for Pantocalcin for children and adults.