One of the best antibiotics that suppress growth and cause the death of microorganisms in dysentery, abscessed pneumonia, Bruce’s disease, typhoid fever and other serious illnesses in humans is Biomycin. The instructions for use describe it as a drug that can simultaneously affect various microbes and is often used in rabbit pasteurellosis for therapeutic and prophylactic purposes. In addition, Biomycin is used to stimulate the growth of young animals as a feed additive.
Description of the drug
"Biomycin" is an antibiotic that is produced by the microorganism Actinomyces aureofaciens. The drug is produced in the form of a yellow crystalline powder, bitter in taste, but odorless. It is poorly soluble in water (at a temperature of +18 only 1.3%), yellow solutions; pH (pH) is from 2.7 to 2.9.
The drug is stable in a slightly acidic environment and in air, but it is easily destroyed in solutions of alkalis and strong acids. The chemical structure allows us to attribute Biomycin to the group of tetracyclines, which also includes Terramycin, Tetracycline and Oxytetracycline.
The activity of the drug is determined by the results of biological standardization and is expressed in units of action (ED) or in weight ratio. One unit is equivalent to 1 μg of chemically pure chlortetracycline hydrochloride.
Ointment "Biomycin" instructions for use describes how a suspension of solid particles in the aqueous phase of the emulsion. This is due to insignificant solubility in water.
“Biomycin”, possessing a wide antibacterial spectrum, is effective against both gram-positive and gram-negative bacteria, as well as rickettsia and certain types of viruses.
Indications for use
"Biomycin" in the form of a solution, ointment or powder can be prescribed for intramuscular administration, as well as external and internal use. With the help of this antibiotic, many infectious diseases are treated (malignant carbuncle, necrobacteriosis, Balkan flu, dysentery, coliparatyphoid infections). At the same time, semi-finished products of the drug, which are added to the feed, accelerate the growth of young animals. "Biomycin" application instruction for animals recommends the use of acute diseases of the gastrointestinal tract and pulmonary diseases of lambs, calves and piglets, as well as with chicken pallorosis.
This broad-spectrum antibiotic can also be used to heal mechanical damage to the covers of aquarium fish.
As for contraindications, the use of "Biomycin" is unacceptable with increased sensitivity to its constituent components.
Dosage and method of administration
“Biomycin” (powder) is recommended for use in the preparation of solutions for intramuscular administration. Despite the fact that the drug itself has an excellent therapeutic effect, the best effect is achieved while taking with sulfa drugs (with the calculation of 0.1-0.2 g per rabbit).
In the treatment of hemorrhagic septicemia, the recommended dose of the antibiotic is determined taking into account the weight of the animal (1 kg of “Biomycin” is needed per 1 kg). The duration of pasteurellosis therapy is 3-4 days, provided that the drug will be administered to sick rabbits twice a day.
In the chronic form of hemorrhagic septicemia, the treatment is different: the first 3 days the animal is given preparations with a wide spectrum of bacteriostatic action, which are included in the group of sulfanilic acid amide derivatives, then the same number of days - “Biomycin”, and at the end again sulfonamide drugs.
When taking antibiotics, you should refrain from feeding the rabbits with silos, which can cause diarrhea.
The solution of "Biomycin" is administered to animals in the latent period, some time before the vaccination. The interval between the first and second injection should be at least 8 hours. Thanks to the use of "Biomycin" the animal is saved from possible death.
Inside, an antibiotic is prescribed to rabbits for diseases of the gastrointestinal tract, less often for colds. The recommended dosage in these cases is 0.1-0.15 g twice a day with a treatment duration of 3 to 5 days. In order to prevent the occurrence of coccidiosis "Biomycin", the instructions for use allow you to give rabbits mixed with food at the rate of 0.01 g per animal. Prevention is recommended to continue for 5 days.
Within 1.5-2 months, to accelerate the growth and development of young animals, starting from 20 days of age, you can give 0.005-0.1 g of the drug "Biomycin." Instructions for use in veterinary medicine indicate that if the recommended dosages and the timing of use of the antibiotic are not observed, rabbits can die. This is due to the poor tolerance of the drug.
Side effects
Exceeding the recommended doses of Biomycin can cause poisoning. If the drug is used for longer than the prescribed period, stomatitis, vomiting, diarrhea and edema may occur. If such side effects occur, it is necessary to reduce the dose of the drug or to completely abandon the use. The veterinarian will help make a decision after the degree of intolerance to the drug is established.
"Biomycin": instructions for use for chickens
According to laboratory data obtained at the Belarusian Research Institute of Animal Husbandry, the consumption of chickens “Biomycin” over the course of two months accelerated the growth of chickens by 25.5%, while using a pure preparation - by 21%. When feeding birds with fodder and fodder fortified means, their weight increased by 27-29%.
The mass of broilers fed with Biomycin up to two months of age ranges from 1.5 to 1.7 kg. This is quite logical, because under the influence of antibiotics, the growth and development of chickens is accelerated. This drug is in great demand among people involved in the cultivation of poultry for sale, because when taking Biomycin, the growing time is reduced from 91 days to 70.
Approximately the same reaction to an antibiotic in turkeys, ducklings and goslings. "Biomycin" is recommended not to be given in its pure form, but with food.
The cost of the drug and storage conditions
"Biomycin" (instructions for use indicates this) must be kept in a dark and dry place where the temperature does not rise above 20 degrees. Shelf life of the drug is not more than six months.
Despite the fact that the reviews about this antibiotic are mostly positive, some people involved in breeding farm animals are forced to abandon the use of “Biomycin” due to the difficulties that arise with its acquisition in Russia. In veterinary pharmacies, mainly foreign analogues of the drug are offered.