In the article, we consider the spray instruction "Asterisk Noz."
The drug is a vasoconstrictor drug for local use in ENT practice and a decongestant drug.
This product is made in the form of a nasal spray, which is a clear, colorless solution, poured in 30, 20, 15 or 10 ml into plastic bottles equipped with a nebulizer and a special protective polyethylene cap. Vials with medication are packaged in cardboard boxes of 1 pc.
According to the instructions, the Sprocket “Noz” contains the main active element - xylometazoline hydrochloride, as well as some additional substances, which include:
- disodium hydrogen phosphate dodecahydrate;
- disodium dihydrogen phosphate;
- benzalkonium chloride;
- edetate disodium dihydrate;
- sodium chloride;
- purified water.
pharmachologic effect
In the spray "Zvezdochka Noz" xylometazoline hydrochloride - the main active substance, is an alpha-adrenergic agonist (vasoconstrictor). This chemical substance, providing narrowing of blood vessels of the nasal mucosa, helps to eliminate its hyperemia and swelling. Against the background of rhinitis, it greatly facilitates nasal breathing. The effect of the drug is observed a few minutes after nasal administration and lasts for several hours.
With local use, the drug is practically not absorbed into the bloodstream, its plasma concentration is so low that it cannot be established using modern analytical methods.
Indications for the use of a pharmacological preparation
As the instruction tells us, the spray "Asterisk Noz" is prescribed when the following pathological conditions occur:
- respiratory diseases with manifestations of acute rhinitis (with symptomatic therapy);
- acute allergic rhinitis;
- sinusitis;
- eustachitis;
- hay fever;
- otitis media (in order to reduce the manifestations of swelling of the mucous membrane of the nasopharynx).
In addition, the medicine is used in preparing the patient for some diagnostic procedures in the nasal passages.
Contraindications
In accordance with the instructions for the "Asterisk Noz" spray, absolute contraindications for the use of this medication are:
- atrophic rhinitis;
- tachycardia;
- severe atherosclerosis;
- arterial hypertension;
- condition after transfenoidal hypophysectomy;
- glaucoma;
- indications of a history of operative manipulations on the meninges;
- inflammatory lesions of the skin or mucous membrane in the nose;
- thyrotoxicosis;
- age less than 6 years;
- pregnancy period;
- concomitant use with monoamine oxidase inhibitors, decongestants, tricyclic antidepressants, medications that increase blood pressure;
- high sensitivity to any of the elements of the drug.
With caution, this medication is used in the following cases:
- coronary artery disease;
- pheochromocytoma;
- diabetes;
- lactation period;
- prostatic hyperplasia;
- high sensitivity to adrenergic drugs, accompanied by arrhythmia, dizziness, insomnia, increased pressure, tremor.
This must be considered before starting the reception.
Spray "Asterisk Noz" - instructions for use
The medicine is applied intranasally. Recommended dosing regimen for adults and children after 6 years of age: 1 spray injection in each nasal passage 3 times a day. You should not use this medication more than 3 times a day. Without consulting a specialist, the course of therapy should not exceed 7 days.
With intranasal administration of the spray, the bottle must be kept upright with the spray. After the injection is made, you need to take a light breath with your nose. Next - close the medication with a lid until the next use.
Side effects
When using the medicinal spray for the nose, “Asterisk Noz”, the following negative adverse reactions may occur:
- Digestive system: dyspepsia, nausea, vomiting.
- Nervous system: headaches, insomnia, with long-term use in high doses - depression, paresthesia, fatigue, excessive anxiety, hallucinations, convulsions (in most cases in children).
- Heart and blood vessels: palpitations, increased pressure, arrhythmia.
- Organs of vision: impaired visual function.
- Respiratory system: hypersecretion, dryness of the nasal mucous membranes, sneezing, tingling in the nose, nosebleeds, reactive hyperemia (increased swelling).
- Immune system: hypersensitivity.
- Local reactions: burning at the site of intranasal administration.
If the above pathological phenomena occur, you must stop using the medication and consult a specialist.
Overdose symptoms
In case of accidental poisoning with xylometazoline when taken orally, it may cause: vomiting, fever, nausea, cyanosis, mydriasis, cramping, hypertension, tachycardia, cardiac arrhythmia, cardiac arrest, collapse, pulmonary edema, respiratory failure, depression of the central nervous system, mental disorders.
In this case, gastric lavage, intake of enterosorbents is prescribed, in severe cases, artificial lung ventilation is performed. If necessary, antipyretic and anticonvulsant drugs are used.
What else can you learn from the instructions for the Sprocket Noz spray for children and adults?
Special recommendations
Before conducting therapeutic procedures, thoroughly clean the nasal passages. Do not often and for a long time use the medication "Asterisk Noz" on the background of chronic pathologies of the nasopharynx. Before intranasal administration of the spray, 2 injections must be made into the air, and after the use of the drug, the dispenser should always be closed with a protective cap.
The use of this drug for a period of more than 7 days can lead to a weakening of the therapeutic effect, and also worsen the likelihood of atrophy of the nasal mucosa and reactive hyperemia. In the case of catarrhal pathologies that occur with the formation of crusts in the nose, it is best to use gel medicines.
The medicine "Asterisk Noz" does not adversely affect the ability to drive a car and other mechanisms that require concentration. However, with a prolonged course of therapy with dosages in excess of those prescribed by the doctor, the risk of a systemic effect of the drug increases. In such situations, caution is advised.
Prescription during pregnancy and lactation
Use of this pharmacological drug during pregnancy is contraindicated. During lactation, the Sprocket of Noz spray can be used only after the recommendation of a specialist.
The use of medication in children
Children under 6 years of age, the medicine "Asterisk Noz" is not prescribed. At an older age, the use should occur strictly under the supervision of a physician.
Drug interaction
In accordance with the instructions, this medication cannot be used in combination with MAO inhibitors, tri- and tetracyclic antidepressants, other local vasoconstrictors, leading to an increase in blood pressure.
Analogs of this drug
Similar medicines Spray "Asterisk Noz" are:
- "Rino grippostad";
- "For carrying";
- "Galazolin";
- "Influorin";
- "Suprim-NOZ";
- "Dr. Theiss Rinotayss";
- "Xylometazoline-Betalek";
- Snoop
- "Xylometazoline";
- "Tizin Xilo";
- Xylene
- "Xylometazoline";
- "Nosolin";
- Otrivin;
- "Tizin";
- Xymelin
- Xymelin Eco;
- "Rinostop";
- "Evkazolin Aqua";
- Rinorus
- "Sanorin-Xilo";
- Espazolin;
- Rinomaris.
A doctor should select a replacement.
Reviews
About the spray "Zvezdochka Noz" a lot of positive reviews. Patients who have used this spray note that it is very effective and helps to quickly eliminate the symptoms of nasal congestion and excessive mucus secretion. This medication is successfully used in the symptomatic treatment of sinusitis, with severe swelling of the sinuses, as well as with otitis media of various origins.
Despite favorable reviews, there are many indications of the development of adverse reactions when using the medication. Among them, most often there was a burning sensation in the nose, symptoms of dizziness and impaired attention.
We examined the spray "Asterisk Noz" (xylometazoline) and instructions for it.