For what purpose is a drug such as Buscopan prescribed? What does this medicine help from? You will find answers to these and other questions regarding the medication mentioned in the materials of this article. From it you will learn about what contraindications, side effects and indications have this drug, how it should be taken, what is its composition and so on.
Composition, form, description
What is the Buscopan medication (what is this medicine taken for, we will talk a bit further)? According to experts, the main active ingredient of such a drug is hyoscine butyl bromide. Also, its composition includes auxiliary components in the form of starch, calcium hydrogen phosphate, silicon dioxide, colloidal, tartaric and stearic acids.
This medication is available in the form of round, white and biconvex tablets, which are coated with a sugar coating. Also, this drug goes on sale in the form of smooth and oblong ivory candles.
Pharmacological properties
What features does the Buscopan medication have? What is it for? This drug is able to have an antispasmodic effect, which is aimed at the gall bladder, smooth muscles of the genitourinary organs and gastrointestinal tract. Also, as a result of taking this drug, the secretion of food glands is reduced. This medication does not produce an anticholinergic effect on the nervous system.
What other properties does Buscopan have? For headache, this drug is prescribed only if it contains such a medicinal substance as paracetamol. As a rule, this component is part of a product called Buscopan Plus. It has a highly effective antispasmodic effect and quite quickly eliminates the cause of pain, producing a muscle-relaxing effect.
Pharmacokinetic parameters of the drug
What pharmacokinetic parameters does Buscopan have? What is he appointed from? The active component of this drug is characterized by a slight absorption from the digestive tract.
After taking the medicine inside, it is absorbed by 8%. Moreover, the average absolute bioavailability of the drug is 1%. A single dose of hyoscine butyl bromide at a dose of 20-400 mg leads to the highest concentration in the plasma after two hours.
The main distribution of the active substance is observed in the cells of the muscles of the pelvis and abdominal cavity. The interaction of the drug with the movement of choline in the epithelial cells of the human placenta was also noted.
The predominant part of the metabolism of the drug relates to the hydrolysis of the ether bond. The medication is excreted through feces and urine.
The drug "Buscopan": what helps?
What is the purpose of the drug in question for patients? According to the instructions attached to the drug, it is especially effective in:
- spasms of the genitourinary organs and gastrointestinal tract (for example, with pylorospasm, renal colic, intestinal colic and cholecystitis);
- exacerbation of an ulcer of the duodenum and stomach;
- dyskinesia of the gallbladder and bile ducts;
- algodismenorea and so on.
It should also be noted that the medication in question is prescribed to patients before labor.
Contraindications to the use of the drug
Does a drug like Buscopan have contraindications? From what this medicine is used, we described above. As for this section of the article, we decided to tell you about the cases in which this drug is forbidden to be taken:
- kids under 6 years old;
- in the presence of myasthenia gravis, angle-closure glaucoma, megacolony and pulmonary edema;
- in the presence of increased sensitivity to the components of Buscopan.
These contraindications are true when it comes to the tablet form of the drug. As for candles, they are not used for:
- prostate adenoma;
- deviations in the work of the heart and blood vessels of the brain.
Instructions for use of the drug and its dosage
Now you know the list of indications for the use of the drug "Buscopan." Why these pills are needed, we discussed above. Now I want to tell you about the dosage at which this medicine should be taken.
The drug is in the form of tablets intended for oral administration. Patients over 6 years of age are prescribed 1-2 pieces three times a day (drink plenty of water).
As for Buscopan candles, they are used rectally. For patients from 6 years of age, the drug is prescribed in the amount of 1 piece three times a day. Suppositories are preliminarily released from the membrane and inserted into the rectum.
The duration of therapy with such a drug is determined only by the attending physician.
Drug overdose
What are the symptoms of increased Buscopan medication? From what this medicine helps, we have already told. However, abuse is highly discouraged. Otherwise, the symptoms described in the “Side Effects” section may occur.
In such situations, it is necessary to carry out the following treatment procedures:
- washing the stomach of the victim;
- the intake of activated carbon, as well as other means of a similar effect;
- the use of cholinomimetics (intramuscularly or intravenously).
As for other complications, they require symptomatic therapy.
Side effects
Taking the drug in question can cause side effects that are associated with the anticholinergic properties of the drug. As a rule, they are distinguished by rather weak severity and pass as soon as possible without any intervention.
Most often, patients are concerned about:
- peeling of the skin, itching, urticaria, irritation;
- difficulty breathing
- dry mouth;
- arrhythmia and tachycardia;
- problem urination and stuff.
Drug interaction
Simultaneous administration of the drug "Buscopan" and antihistamines, tricyclic antidepressants, "Amantadine", "Hindin" and "Disopyramide" can significantly enhance its anticholinergic effect.
The combined use of the drug in question with dopamine antagonists (for example, metoclopramides) significantly reduces the effect of each drug on the digestive tract.
Combined therapy with beta-adrenergic drugs and Buscopan quite often enhances tachycardia.
Special recommendations
Treatment with this drug requires strict adherence to all medical recommendations. For example, Buscopan therapy should be discontinued gradually. This is due to the fact that a sharp cessation of its intake can easily cause nausea, dizziness and sweating.
It should also be noted that during treatment with "Buscopan" it is necessary to refrain from heavy physical exertion and overheating (you can not stay in the heat, in a hot bath or sauna for a long time).
If dry mouth does not disappear within two weeks, then the risk of damage to the gums, tooth enamel and the development of fungal infections increases significantly.
During treatment with "Buscopan" you must be extremely careful while driving and in other activities that require special attention.
The use of alcoholic beverages during therapy with this drug is strictly prohibited. This is due to the fact that taking ethanol can easily provoke the development of a number of undesirable effects.
Analogues of the drug and its price
Now you know what Buscopan is. From what this drug helps, we also told.
In the pharmaceutical market, this product has no analogues in the active substance. However, the following drugs are included in the list of analogues in the pharmacological group: Atropine, Atrovent, Gastrozem, Gastrocepin, belladonna extract, Driptan, Novitropan, Midriacil, Trigan, Spazmeks and others.
The price of these products may vary depending on the active substance, the manufacturer and the number of tablets in the package. As for the cost of the original product, it ranges from 280 to 380 rubles.
Medication Reviews
This drug is discussed by many patients. Especially often pregnant women speak about them. This is due to the fact that before delivery, Buscopan suppositories are very often prescribed to prepare the cervix for the process. However, most mothers note that the effectiveness of suppositories is not always manifested.
In addition to suppositories, doctors often prescribe to their patients a tablet form of the drug. As a rule, such a medication quite effectively eliminates pain and colic in the abdomen, greatly facilitating the patient's condition.