Cipramil is a known antidepressant that is a selective serotonin reuptake inhibitor. It is used to treat depressive conditions, panic attacks and obsessive-compulsive disorders. In what cases is the drug “Tsipramil” prescribed? Instructions for use, price and possible contraindications are discussed in this article. We will also tell you whether it is possible to take this medicine for pregnant and lactating women.
Composition and form of release
“Tsipramil” is produced in the form of white tablets, film-coated, labeled “C” and “N”.
The active substance is citalopram hydrobromide. Among the auxiliary components include the following: glycerin (85%), magnesium stearate, lactose monohydrate, copovidone, etc. The shell consists of macrogol 400, titanium dioxide, hypromellose 5.
The drug goes on sale in blisters for 14 tablets, which are in a cardboard box.
pharmachologic effect
The drug “Tsipramil”, reviews of real patients about which are presented a little later in this article, is a very effective antidepressant. The medication does not differ in the ability to bind to receptors. According to the instructions, it inhibits cytochrome P450IID6, due to which it does not interact with other drugs that are directly metabolized by this enzyme.
The drug does not affect the functioning of the conduction system of the heart, blood pressure, the functioning of the liver, as well as hematological parameters. The claimed antidepressant effect is manifested after 2-4 weeks of systematic use. Using the medication on a regular basis does not entail an increase in patient weight.
After oral use, the bioavailability of the active component is approximately 80%. Its maximum concentration in the blood is reached after approximately 2-4 hours from the time of administration. The active substance of the drug is excreted along with feces and urine.
Indications for use
In what cases is Tsipramil prescribed? Instructions for use states that this drug is especially effective for prolonged depression and panic attacks. In addition, it is recommended to patients to eliminate feelings of causeless anxiety and so-called agoraphobia. In some cases, a medication is prescribed for obsessive-compulsive disorders.
Contraindications
To whom is Tsipramil categorically contraindicated? Instructions for the use of the drug indicate that the drug should not be taken by patients with hypersensitivity to one or more of the components that make up its composition. In addition, during pregnancy and lactation it is better to abandon its use. The use of the medication is possible only on the advice of a doctor.
The drug "Tsipramil": instructions for use
Therapy is prescribed by a specialist individually.
For depression, the daily dose of Cipramil is 20 mg, taken once a day. According to the doctor’s recommendations, based on the characteristics of the disease, in some cases it is increased to 60 mg. Usually, after two weeks of treatment, the expected antidepressant effect begins to appear, but this does not mean that therapy should be discontinued. To prevent exacerbation of relapses, it is continued for six months.
If a patient is concerned about panic attacks, many doctors also prescribe Cipramil. The instruction for the use of the tablet medicine states that already in the third month of therapy, the desired effect can be expected. Patients in the first week of treatment are usually prescribed 10 mg of the drug once a day, and in the second week - 20 mg. This dosage remains unchanged until the end of the course of therapy.
Daily requirements may vary depending on the patient's age, his general condition and the nature of the nervous pathology. For example, persons with renal insufficiency “Tsipramil” should be taken in smaller volumes (no more than 30 mg per day).
Overdose and side effects
As already noted above, only on the advice of a doctor can you take "Tsipramil". Side effects, reviews of a negative nature clearly prove that the use of a medication in self-medication can significantly worsen the quality of life and the condition of the patient.
When using Tsipramil in an increased dosage, the following symptoms may appear: drowsiness, tachycardia, increased sweating, cyanosis, and vomiting. Based on the fact that a specific antidote does not currently exist, the treatment of this condition should be symptomatic. After taking the tablets, the patient urgently needs to do a rinse, give activated charcoal and immediately seek qualified help.
Pregnancy and lactation
The safety of the drug during lactation or during pregnancy has not been established. The use of Cipramil is justified only when the potential benefit of therapy for a woman significantly exceeds the probable risk to the fetus inside the womb or newborn.
According to the results of experimental studies, no teratogenic effects or negative effects on the reproductive capabilities of the female body were detected.
Drug interaction
How does “Tsipramil” manifest itself with other medicines? Side effects, reviews of a negative nature with chemical incompatibility of this drug were not observed. Combination with MAO inhibitors can provoke symptoms of a hypertensive crisis.
Experts warn that the simultaneous use of the medication and the use of alcohol are not recommended. No pharmacodynamic interaction between cardiotropic drugs and this antidepressant was detected.
special instructions
The experience of treating women in the position of this drug is very limited, so if possible it is better to abandon it. With extreme caution, it is necessary to take medication for persons who are constantly behind the wheel of a car, or their direct labor activity is associated with the maintenance of precise mechanisms.
On the other hand, the activity of the drug in the body does not affect the intellectual function and psychomotor reactions. However, it is extremely important to keep in mind that in patients with diagnosed depression, a decrease in the ability to constantly concentrate is often observed. This may be aggravated when using psychotropic medicines.
All patients, without exception, receiving antidepressant therapy, require constant medical supervision. Particular attention should be paid to patients at the beginning of the course of treatment, when the likelihood of manifestation of suicidal tendencies increases.
The drug "Tsipramil": analogues and prices in pharmacies
The following are analogues of this drug: “Oropram”, “Citalon”, “Cytol”. All medicines have their own characteristics, contraindications and methods of use. That is why it is important to consult a doctor before using them.
How much is Tsipramil? The price in pharmacies for this drug may vary. On average, tablets will have to pay about 900 rubles. The final cost usually depends on the margin of the pharmaceutical company.
Reviews of real people
Is Cipramil Really Effective? Reviews about this drug are the most mixed, but in most cases they are positive.
According to many patients, Tsipramil is a very “serious" medicine. The expected result usually does not come immediately, as we would like. Its reception usually lasts for months. Patients are warned in advance that the effect can be expected no earlier than 2-3 months after the start of therapy. The standard course of treatment is six months. During this period, patients experience a visible improvement. Moreover, some note a complete restoration of health.
It should be noted that the drug has an addictive effect. It is recommended to cancel it gradually to avoid relapse. The prognosis for treatment is favorable only if the medicine is prescribed by a competent specialist. You should not resort to the help of a medication simply because of “sudden depression”. The thing is that its systemic influences and the difficulty in choosing the right dosage can aggravate the condition.
Storage conditions and shelf life
How long can Tsipramil be stored? The instructions for this medicine indicate that the drug should be stored in places inaccessible to children's hands, reliably protected from sunlight. Shelf life is five years.