Many are exposed to stressful conditions today. Constant tension and anxiety lead to the development of symptoms such as headache, fatigue, sleep disturbance. To avoid more serious complications, it is necessary to take a vitamin course, which will help restore lost strength, give vitality. Good reviews can be heard about the Milgamma Compositum. Instructions for use, analogues - all this information should be studied before starting treatment.
Release form
The medicine contains a complex of vitamins of group B. It is produced in the form of a white dragee. The main components in the composition of the product are benfotiamine (100 mg) and pyridoxine hydrochloride (100 mg).
The complex vitamin preparation has a positive effect on the nervous system. Benfotiamine is a fat-soluble derivative of vitamin B1. Participates in the process of glucose synthesis. Helps the body restore energy spent, increase immunity.
Pyridoxine hydrochloride (vitamin B6) is involved in the formation of active amines,
transamination of amino acids, is involved in anabolic and catabolic processes, as well as the decomposition and synthesis of amino acids. To easily cope with stress and normalize sleep, you need to take the Milgamma Compositum dragee. Reviews analogues also have positive. The most popular substitutes will be described below.
Pharmacokinetics
Once inside the body, most of vitamin B1 is absorbed in the duodenum, the smaller - in the small intestine. Especially high levels of coenzyme concentration are observed in the brain, blood, liver, and kidneys. Vitamin B6 is mainly absorbed in the upper stomach in a passive form. In blood serum, the drug combines with albumin. Both vitamins are mainly excreted in the urine. The maximum activity of the drug is achieved two hours after administration.
Indications and contraindications
The drug is prescribed for neurological pathologies, when there is a deficiency of vitamins B1 and B6. Also, medication is indicated for stressful situations, after severe intoxication and severe illness.
Contraindications:
- childhood;
- heart failure;
- gestation;
- lactation;
- hypersensitivity to the components of the drug;
- fructose intolerance.
Before starting treatment, it is necessary to carefully study all contraindications for the use of Milgamma Compositum tablets. Analogs are also worth using after studying this information.
Dosage
The medicine is prescribed orally. Adults need only one tablet once a day. The tool should be taken without chewing and drinking plenty of water. In rare cases, on the recommendation of a doctor, a medicine is prescribed three times a day. The daily norm can be adjusted depending on the severity of the disease, as well as the individual characteristics of the body.
The risk of overdose is low. Only in rare cases, a manifestation of neurotoxic effects can be observed. With a long course and increased dosage, neuropathy may develop. Also, taking the drug in high doses can trigger seizures. In case of symptoms of poisoning, the patient needs to rinse the stomach, give a sorbent to drink and use detoxification therapy.
Interaction with other drugs
Co-administration with such groups of drugs is not recommended:
- agents that are antagonists of vitamin B6;
- contraceptives that have estrogens in their composition;
- ethanol-based drugs;
- preparations containing fluorouracil.
Any analogue of Milgamma Compositum tablets will have the same recommendations.
Side effects
Basically, the vitamin complex is well tolerated by patients. But in exceptional cases, the following reactions can be observed:
- allergy, which is characterized by skin rashes and may be complicated by Quincke's edema and anaphylactic shock;
- headache, sensory neuropathy with a long course;
- nausea;
- increased sweating;
- acne;
- tachycardia.
special instructions
It is not recommended to take the medicine in childhood and in patients with pathology of the kidneys and liver. The drug must be stored at a temperature of no more than 25 degrees, in a dry place inaccessible to children. In a pharmacy, the Milgamma Compositum tablets are dispensed without a prescription. Analogs (domestic or foreign) should be used after consultation with a specialist. Next, we consider some of them in more detail.
Vitagamma
The medicine is a complex of B vitamins. The product is available in the form of a solution for intramuscular injection. The main substances in the composition of the drug are lidocaine hydrochloride, pyridoxine hydrochloride, thiamine hydrochloride and cyanocobalamin. The solution is packaged in dark ampoules of 2 ml each.
Vitamin complex helps to normalize metabolism, improve the function of motor, sensory and autonomic nerves. Participates in nerve impulses, has antioxidant activity, accelerates regenerative processes in the nervous tissue, participates in the synthesis of myelic acid. To restore the strength of the body, increase immunity, it is necessary to take a course of taking the drug "Vitagamma". The same effect is exerted on the body by Milgamma Compositum. Analogs can fully replace it, since they have an identical composition and indications for use.
Indications, contraindications, side effects
Individually, the drug is prescribed for neurological problems associated with vitamin B deficiency. The complex is indicated for neurological diseases of various etiologies.
Contraindications:
- varicose veins;
- childhood;
- pregnancy;
- breast-feeding;
- low pressure;
- hypersensitivity to the components of the solution.
With prolonged use of the drug, the following side effects may develop:
- tachycardia;
- allergic reactions;
- cramps
- excitation;
- pressure reduction;
- increased sweating.
A cheap analogue (Milgamma Composite - a rather expensive remedy), Vitagamma, can be purchased at almost any pharmacy.
Mode of application
The solution is administered intramuscularly once a day. The course of treatment is from 5 to 7 days, taking into account the severity of the disease and the individual characteristics of the body. If necessary, then after a week's intake, you can inject the medicine every other day in the same dosage for up to one month.
Kombilipen
This is also a complex of vitamins of group B. The product is made in the form of a pink solution with a specific smell. The main components in the composition of the drug are vitamins B1, B6 and B12, as well as lidocaine hydrochloride. It is produced in dark ampoules of 2 ml of solution in each.
A multivitamin preparation of a combined composition helps with degenerative and inflammatory processes in the nervous system and musculoskeletal system. Participates in the conduct of a nerve impulse, metabolism, is necessary for normal blood formation.
Lidocaine, which is part of the drug, has an anesthetic effect, dilates blood vessels, and promotes the rapid absorption of vitamins. The drug “Combilipen” can be prescribed alone or in combination with other means. It is a substitute for the famous Milgamma Compositum. The Russian analogue is available at any pharmacy and has an acceptable cost.
Indications and contraindications "Combilipene"
The drug in complex therapy is used for the following diseases:
- various forms of neuralgia;
- diseases of the spine and pain associated with this pathology;
- polyneuropathy of different origin.
Contraindications:
- severe form of cardiovascular disease;
- pregnancy;
- breast-feeding;
- childhood;
- hypersensitivity to the components of the drug.
Dosage "Combilipen"
The drug is administered intramuscularly once a day for 10 days. Further, if necessary, you can inject the solution every other day. The course of treatment is one month. It is imperative to inject the drug deep into the muscle and only with a sterile syringe.
Overdose
In rare cases, the following symptoms may develop:
- tachycardia;
- increased sweating;
- allergy.
If an overdose occurs, the patient needs to undergo detoxification therapy and prescribe somatic treatment.
Reviews
Specialists speak positively about the Milgamma Compositum. Analogs also have good reviews. The described agents can be purchased in the form of tablets and an injection solution. After the course, the body's immunity rises, inflammation and pain in the spine go away, the causes of stress are eliminated and sleep is normalized. At the beginning of treatment, you can inject the medicine for seven days, and then switch to the tablet form.
Experts note that the complex of vitamins of group B has a good effect on hair growth, skin and nails. It is recommended to undergo a course of therapy once a year if there is a deficiency in the body. The medicine is especially useful for degenerative changes in the cervical, lumbar and thoracic spine.
Only after studying the instructions and consulting with a doctor, it is worth using the drug Milgamma Compositum. Self-medication is undesirable. Negative reviews provide an opportunity to understand that neglect of the doctor’s recommendations can lead to the development of side effects.
Other analogues:
- "Neuromultivitis";
- Binavit
- "Neurobion";
- "Neurorubin";
- Neurobeks.