A delicate problem, such as diarrhea, was faced by everyone. The cause of its occurrence may be different. However, they are not always detected after the first visit to a doctor. Therefore, to eliminate this condition, experts recommend taking the drug "Diara".
Instructions for use, consumer reviews on the effectiveness of this drug, we will present a little lower. Also in this article you will find information on how you can replace the drug in question, in what form it is made, etc.
Form, description, packaging and composition
In what form can I buy the medicine "Diara"? Analogs of this medication are found in various forms. However, the product we are considering is sold only in the form of chewable tablets in white or with a yellowish tinge. They have a cylindrical shape, at risk, light marbling and anise flavor.
The active ingredient in this medicine is a substance such as loperamide hydrochloride. Chewing tablets also include the following auxiliary elements: colloidal silicon dioxide (or the so-called aerosil), polymethylsiloxane, microcrystalline cellulose, potato starch, lactose, povidone (or collidone 90), aspartame, collidone SR, xylitol, menthol, lactitol, anise oil and magnesium stearate.
The anti-diarrheal preparation is packaged in contour cells and packs of cardboard, respectively.
Features of the drug
What is remarkable for the Diara medication? Instructions for use states that it is a symptomatic antidiarrheal agent. Its active substance binds to opioid receptors, which are located on the walls of the intestine. Thus, modulation of adrenergic and cholinergic neurons via guanine nucleotides occurs.
Also, loperamide hydrochloride reduces the motility and tone of the smooth muscles of the intestine. This process is carried out by inhibiting the release of prostaglandins and acetylcholine. In addition, taking "Diara" helps to slow intestinal motility and increases the transit time of its contents.
The drug in question increases the tone of the anal sphincter, holds feces and reduces the urge to defecate. Its action occurs very quickly and lasts for 4-5 hours (sometimes longer).
Kinetic properties of antidiarrheal agents
Is the medication “Diar” (tablets) metabolized? The instruction states that the metabolism of loperamide hydrochloride is completely carried out in the liver through conjugation.
The half-life of this medicine is 9-15 hours. The drug is excreted mainly with bile, as well as together with urine in the form of metabolites (conjugated).
Indications for taking chewable tablets
Do you know about the purpose of prescribing the medication "Diar"? The use of this drug is indicated for:
- changes in diet, as well as the quality of food;
- malabsorption of food and metabolism;
- chronic and acute diarrhea of various origins (including allergic, emotional, drug and radiation);
- stool regulation in people with ileostomy.
Among other things, such tablets are very often used as an adjuvant for diarrhea, which has an infectious origin.
Contraindications to taking pills
What are the contraindications for the Diar medication? Instructions for use states that there are quite a few prohibitions on this medicine. These include the following diseases and conditions:
- intestinal obstruction;
- diverticulosis;
- diarrhea, which is observed against the background of acute pseudomembranous enterocolitis ;
- first trimester of pregnancy;
- ulcerative colitis, especially in the acute phase;
- breast-feeding;
- monotherapy of dysentery, as well as other infectious diseases of the digestive tract;
- hypersensitivity of the patient to the ingredients of the drug;
- age to six years.
It should also be said that the carefully considered medication is recommended for liver failure.
Chewable tablets "Diara": instructions for use
This medication must be taken orally. Chew the tablet thoroughly, and then wash it down with plain water.
The dosage of this medicine for adults and young children varies significantly.
- For adults with chronic or acute diarrhea, tablets should be taken in an initial dose of 4 mg (i.e. 2 pieces). After this, the drug is prescribed 2 mg (1 tablet), which is taken after each act of defecation (in the presence of loose stool). The permissible daily dosage of this drug is 16 mg or 8 tablets.
- For children over 6 years of age, with acute diarrhea, the drug is recommended to be taken in an initial dose of 2 mg or 1 tablet. Then the medication is given to the child in the same amount, but after each bowel movement (in the presence of loose stools). The permissible daily dosage for children from six years is 6 mg or three tablets.
After normalization of the stool or its absence for more than 11 hours, treatment with "Diaroy" must be stopped.
Side effects
Can the Diar medication cause unwanted reactions? Patient reviews report that while taking chewable tablets, they often have side effects.
From the digestive organs, gastralgia, intestinal colic, dry mouth, vomiting, intestinal obstruction, nausea and constipation develop.
On the part of the nervous system, a person may experience dizziness and drowsiness.
It should also be noted that while taking antidiarrheal tablets, some people have allergic reactions in the form of a skin rash.
Overdose Signs
Only a doctor can prescribe the correct intake of Diara. The instructions for use report that if the dosages of this medicine are not observed, the patient may experience the following undesirable symptoms: drowsiness, central nervous system depression, stupor, miosis, impaired coordination of movements, muscle hypertension, intestinal obstruction and respiratory depression.
As a treatment for such conditions, an antidote, Naloxone, is used. Due to the fact that the duration of action of the active substance "Diara" is longer than that of "Naloxone", it may be necessary to re-introduce it.
As for symptomatic therapy, for its implementation the patient is given activated charcoal and the stomach is washed.
Under medical supervision, the victim should be for two days.
Special recommendations
If the effect of taking the drug is absent, then it should be canceled. You also need to see a doctor to prescribe another drug.
Analogs and cost
If necessary, Diara can be replaced with medicines such as Loperamide, Stoperan, Enterofuril, Lopedium, Entoban and others.
You can buy an antidiarrheal agent at a very reasonable price (about 55-65 rubles).
Consumer Reviews
Along with "Loperamide", the drug "Diara" is especially popular with that category of people who regularly suffer from loose stools. According to their reports, this medication effectively copes with the task.
After several doses of chewable tablets, the bowel movement noticeably decreases, and the stool becomes thicker.
The only drawback of this medicine, patients consider the presence of a large number of contraindications.