Many people do not even suspect that disruption of the thyroid gland can cause a lot of problems. Irritability, fatigue, insomnia, swelling - this is only a small part of the clinical manifestations of thyrotoxicosis that patients experience. The consequence of this ailment is a long-term therapy to restore thyroid function and support its condition. In such cases, endocrinologists prescribe the drug "Merkazolil" to patients, analogues of the drug are also prescribed, but a little less often. It is with these medications that help restore the functioning of the thyroid gland and establish the usual pace of life, we will try to understand in more detail.
The drug "Merkazolil"
Before considering the analogues of this medication, its pharmacological properties and other characteristics should be studied.
The drug "Merkazolil" has antithyroid properties and is an antagonist of thyroid hormones. In other words, the drug inhibits the synthesis of thyroxine in the thyroid gland, and therefore, contributes to the normalization of metabolic processes in it.
However, it is worth noting that with diffuse toxic goiter, not only the Merkazolil drug is prescribed. Analogues of the drug, based on the same active substance (tiamazole), are also used quite often.
Means "Tyrosol"
Doctors prescribe this drug to many patients who are diagnosed with thyroid hyperthyroidism. It blocks the enzyme peroxidase, which is involved in the iodination of thyronine. Thanks to this action, the drug is effective for thyrotoxicosis. Do not use the drug with thyroiditis and after treatment with radioactive iodine.
Like the drug "Merkazolil", this medication has many side effects from almost all important body systems. In addition, the active ingredient in these two drugs is identical. Therefore, it is unambiguous to answer the question of “Merkazolil” or “Tyrosol” - which is better, only a doctor can in each case.
The drug "Tiamazole"
Since thyrotoxicosis is today a fairly common ailment throughout the world, the list of drugs that can restore the correct functioning of the thyroid gland is quite wide. Therefore, you should not think that with hyperthyroidism only Merkazolil or Tyrozol can help, many other drugs, including the Tiamozol, can be used for systemic therapy.
It can be prescribed both for medical treatment of the disease, and for preparing patients for the surgical method of getting rid of the disease. In addition, this tool is used to prevent hyperthyroidism in combination with radioactive iodine therapy.
The medicine "Favistan"
Not many of those who have encountered the problem of thyrotoxicosis know about the existence of this synthetic antithyroid drug, which is produced in Germany. It is able to lower the level of basic metabolism and reduce the synthesis of thyroxine, more gently affecting other important systems of the body. In other words, the medicine is effective for thyrotoxicosis, but has fewer side effects than the Merkazolil agent. Analogues of this drug also exist, but, unfortunately, are used only in Western countries.
The drug "Espa-Karb"
The basis of this tool is the substance carbimazole, which, depending on the dose, affects the synthesis of thyroid hormones and helps inhibit the incorporation of iodine into tyrosine. This action of the drug allows symptomatic treatment of the gland, regardless of the etiology of the disease.
The drug is indicated for patients with hyperproduction of thyroid hormones, as well as in preparation for thyroidectomy. The medicine can be used before taking radioactive iodine and after therapy.
It is worth noting that, like the Merkazolil agent, its analogues have many side effects. Reviews confirm this. But, unfortunately, it is impossible to restore the proper functioning of the thyroid gland without medication. Therefore, the doctor, taking into account the individual characteristics of the patient, selects a safer drug. Self-administration of antithyroid drugs or their replacement can aggravate the course of the disease and lead to irreversible consequences in the body.
Which drug is better? Patient opinion
Talking about which drug is better is impractical even to those who have experienced their effects on themselves. After all, the human body is completely individual, therefore, the reaction to the same medication is different for everyone. In addition, the etiology even with the same degree of thyrotoxicosis can be different. So it turns out that one person who took "Tyrozole" leaves the best reviews, and the other patient does not have positive dynamics, therefore, his opinion about the drug is not high. This is only one of the cases that proves that holding a discussion about which medication is better is pointless. It would be more correct in such a situation to trust the attending physician, who monitors the dynamics of the ailment, and take the prescribed medications, whether it is the drug “Merkazolil”, the analogues mentioned above, or other medications.