There is an opinion among the population that there are substances that can inhibit oxidative processes in the body caused by the destructive effect of free radicals, thereby slowing down the aging of cells. These substances can be of natural or synthetic origin, and they are called antioxidants. One of these drugs, belonging to the antioxidant group, is Neurox. The use of the drug is better to start as directed by a doctor than to prescribe it yourself. This is due to the opinion of medical experts that food additives containing antioxidants in their composition can be dangerous to humans and can harm their body.
Main components
The main component of the drug is eilmethylhydroxypyridine succinate, the dose of which in 1 ml of the substance is 50 mg. In addition, the drug includes auxiliary components: sodium disulfate - 1 mg, water for injection - not more than 1 mg. The release form of the Neurox drug is injections. Instructions for use are always attached to the drug, which is offered to customers in ampoules of 2 or 5 ml. Ampoules are packed in cardboard boxes of 5, 10, 20 pieces (50 ml can be packed in 2 ml).
Exposure to the body
Neurox, reviews of which are both positive and negative, reliably protects the membranes of neurons (brain cells) from any external influences. The presence of this drug promotes more efficient blood circulation in the vessels of the brain, which, in turn, improves saturation neurons with oxygen. Under the influence of "Neurox" in the brain increases the concentration of dopamine (in other words, this substance can be called the hormone of pleasure) .This leads to the fact that fear and tension go away, anxiety is relieved a person taking “Neurox” is able to withstand stress more effectively. It activates mental activity, reduces the likelihood of developing convulsive states, normalizes the cyclic nature of sleep-wakefulness processes. It has Neurox indications for use and, if necessary, normalization of metabolic processes in ischemic myocardium.The drug will reduce the necrotic zone, restore (or significantly improve) the contractility of the heart muscle, its electrical activity.
With intramuscular administration, the effect of the influence of Neurox will last up to 4 hours. To achieve the highest concentration, 20 to 40 minutes after injection are necessary. The main active ingredient quickly passes from the blood to organs and tissues. The drug is excreted from the body with urine, previously decomposed in the liver into metabolic products.
Indications for use
The antioxidant drug "Neurox" is prescribed as part of complex therapy for any cerebrovascular accident. Neurox is indicated for use as a drug that is effective as part of complex therapy for ischemic strokes and its various consequences. The use of a drug for neurocirculatory dystonia and discirculatory encephalopathy will be justified. It is appropriate to use the drug in neurotic and neurosis-like anxiety conditions, a good effect can be expected if it is necessary to relieve withdrawal symptoms in alcoholism, and poisoning with antipsychotic drugs.
We can talk about the effectiveness of the drug with the appearance of disorders of attention and memory, a decrease in the level of performance. For the elderly, its use in neurological and mental age-related problems, cerebral arteriosclerosis is relevant.
In addition, Neurox (injections) instructions for use are positioned as an effective drug in such acute purulent-inflammatory processes of the abdominal cavity as acute necrotic pancreatitis and peritonitis (as part of complex therapy).
Who should refrain from taking?
A contraindication for taking absolutely any drug is the individual intolerance of its components. This is relevant for the drug "Neurox". Instructions, reviews of experts do not recommend introducing it to people suffering from acute disorders in the functioning of the kidneys and liver. Pregnancy and lactation are also an undesirable time for the use of the drug, since there is currently no clinical experience with the use. In addition, there are age restrictions - children under 18 years of age (efficacy and safety have not been determined).
Caution should be given to people with a history of allergic diseases and reactions.
Dosage regimen
The dosage regimen of the Neurox preparation, the instructions for use (the price of the medicine, by the way, is directly dependent on the volume of the package), are recommended to be selected specifically for a particular patient, focusing on his health condition and the presence of certain diseases. The release form of the drug allows you to enter it intramuscularly or intravenously in the form of injections. In a jet, the drug is administered no faster than 5-7 minutes. With the drip method, from 40 to 60 drops in one minute. Usually, the appointment of the drug begins with a dose of 50-100 mg. Injections can be made from one to three times during the day. Further, the dose is gradually increased until a stable therapeutic effect is obtained. The maximum possible volume of Neurox is not more than 800 mg in 1 day.
If patients have acute circulatory disorders in the brain, 200-300 mg of the drug is administered intravenously (once) in the first 2-4 days. Further, until the end of the course, 100 mg is administered intramuscularly three times a day. If the patient suffers from various kinds of neurosis, neurocirculatory dystonia, he is usually prescribed to inject from 50 to 400 mg of the drug intramuscularly during the day for 2 weeks.
With discirculatory encephalopathy in the stage of decompensation, the course of treatment can last up to 28 days. The first half of the treatment period (2 weeks), the patient is given intravenous injections of 100 mg of the drug 2-3 per day, depending on the state of health. Further to the end of the course - one injection per day intramuscularly without changing the dose. For prophylactic purposes, with such a disease, intramuscular injections of 100 mg of Neurox are made twice a day. The total treatment period can be from 10 days to 2 weeks.
In patients with alcoholism, in order to relieve very unpleasant manifestations of withdrawal symptoms, injections can be made intramuscularly at 100-200 mg 2-3 times a day, or intravenously 1-2 times a day with a dose. The course of treatment usually lasts 5-7 days.
When various types of antipsychotics are poisoned, doctors prescribe intravenous injections with a total daily dose of 50 to 300 mg of the drug. The course can last 1-2 weeks.
In elderly patients with mild cognitive impairment, the treatment period can last from 2 to 4 weeks. The total dosage per day is usually 100-300 mg of Neurox.
Exceeding the permissible dose: consequences
When taking Neurox, increasing the dose above the maximum permissible can cause a disturbance in the cyclic nature of the sleep process (difficulty falling asleep or drowsiness). If the drug was administered intravenously, then blood pressure may slightly increase over the course of 1.5-2 hours. Usually, in some special therapeutic measures is not necessary, the symptoms of an overdose disappear on their own within a day. If the consequences are quite pronounced, then with difficulties falling asleep, the use of one of the following drugs is indicated: Nitrazepam (10 mg), Oxazepam (10 mg), Diazepam (5 mg). If blood pressure has risen to sufficiently serious indicators, you may need to take antihypertensive drugs. The pressure must be constantly monitored.
It should be especially noted that during treatment with Neurox care must be taken when driving a car. In general, any activities requiring concentration and rapid psychomotor response should be performed with caution.
Price range
The price of Neurox (injections) varies depending on the form of release and the number of ampoules in a box. A package of 5 ampoules of 5 ml is offered to customers at a price of 260 to 318 rubles. A package of 10 ampoules of 2 ml can be purchased for an amount from 308 to 420 rubles. However, from a financial point of view, it is more profitable to purchase a package of 50 ampoules of 2 ml each, the cost of which is in the range from 970 to 1070 rubles.
As for the substituents of the Neurox drug (analogues), the price of them has a wide spread and depends on the form of release and the size of the package. For example, the price range of the Mexidol preparation is from 80 to 460 rubles; "Krestor" can be purchased for the amount of 500 to 4500 rubles.
The opinion of consumers about the drug "Neurox"
Having got acquainted with the opinions of people, one can see that reviews on the Neurox drug are not always positive. On the one hand, patients with degenerative lesions of the nervous system write that after a course of various supporting drugs (including Neurox, among others), the physical condition improves significantly, weakness disappears, and it becomes easier to move.
On the other hand, patients with vegetovascular dystonia did not see any visible improvements after a course of treatment with Neurox. Some patients with headaches and vasospasms also did not receive the expected effect.
In such cases, it is important to find a competent and interested doctor in your patient. It is such a doctor who will be able to choose the most compatible drugs for treatment, correctly select the dosage for the needs of this particular patient. Without such a regimen, Neurox is a simple tool that provides the potential to achieve a good result. If the instrument is tuned, a positive effect will be obtained, there will be no effect.
Another specific group of patients expressed their opinion about the Neurox drug: in patients with alcoholism, the antioxidant effectively removes withdrawal symptoms caused by the sudden withdrawal of alcohol. Even the occurrence of small side effects from taking the drug does not detract from the positive impact on health.
Side effects
Almost any drug in the process of taking one or another side effect can be observed. Neurox was no exception. Reviews of patients and medical workers report the possibility of side effects of the use of the drug, especially if it is administered jet, intravenously. Of the most pronounced - a feeling of dry mouth, an unpleasant "metallic" taste. In addition, there may be a kind of “hot flashes” (a sensation of heat spreading over the body), an unpleasant sore throat. If the drug is administered at a faster rate than prescribed by the instructions, discomfort in the chest area may appear, a feeling of lack of air. As a rule, such manifestations are short-term in nature.
The drug "Neurox", the indications and the need for the use of which are evaluated by the attending physician, with a long period of administration can cause nausea, increased gas formation in the intestine, until the appearance of intestinal colic. Possible sleep disorder: insomnia or persistent feeling of drowsiness.
Analogs
The antioxidant Neurox has analogues in many drug groups. Similar in the medical field are called interchangeable drugs that have similar indications for use and belong to the same pharmacological group. Neurox has a lot of analogues, but before you buy any of them, you must consult with a specialist about a replacement. In addition, you need to study the instructions for use of the drug "Neurox", reviews about it and the proposed analogue.
Drugs from the nootropin group (Piracetam) have a similar effect to Neurox on the human body. Nozepam and Sibazon - benzodiazepine tranquilizers - are also analogues of Neurox. Drugs that regulate cerebral circulation (Vinpocetin) and antioxidants (vitamins C and E) have a similar effect on the body.
Vinpocetine is one of the most famous analogues of the Neurox drug for a wide range of consumers. Instructions for use (the price of both drugs is close to each other) recommends taking "Vinpocetine" for those patients who have problems with cerebrovascular insufficiency (encephalopathy, various stages of stroke, ischemic attack). Also, the drug is prescribed to those who have mental disorders and neurology, manifested in impaired memory and motor coordination, in headaches and dizziness. Ophthalmologists prescribe Vinpocetine for patients with vascular diseases of the retina, lining of the eye, in the presence of symptoms of secondary glaucoma. In otolaryngology, this analogue of "Neurox" is prescribed by specialists in developing senile hearing loss, with dizziness.
One of the often used analogues of Neurox is Mexidol. The drug is prescribed in the presence of acute cerebrovascular accidents and diseases caused by such disorders. Indication for the use of Mexidol is a violation of the functioning of the autonomic nervous system (vascular tone decreases). Also, the drug can be prescribed to relieve withdrawal symptoms (occurs after the sudden cessation of alcohol, drugs) in people with alcoholism or drug addiction.
It has Neurox analogues in the group of drugs designed to combat high cholesterol. One of these - "Crestor" - is prescribed if the patient has such a disease as hypercholesterolemia. The drug is prescribed both at the initial stage of the disease (type 2a), but in a mixed form (type 2b), if non-pharmacological methods (changing the diet, physical activity, weight loss) did not give the desired effect.
Insufficiency of cerebrovascular activity (mismatch of the brain’s oxygen demand with its intake) can be regulated by such an analogue of Neurox as Vazobral. The drug is successfully used for cerebral atherosclerosis, effective in reducing mental activity and attention, impaired memory and orientation in space. Specialists prescribe Vizobral for prophylaxis for patients suffering from migraine, dizziness, tinnitus, and damage to the walls of the vessels of the retina (retinopathy). The drug is also effective in chronic venous insufficiency.
Vijaysar is another analogue of the Neurox drug. Instructions for use, reviews of patients and specialists characterize it as an effective tool for normalizing blood glucose levels and for patients with non-insulin-dependent diabetes mellitus. In addition, the drug can be recommended for the prevention of cardiovascular diseases (hypertension, ischemia, atherosclerosis). A drug is used in the presence of chronic diseases of the liver, gastrointestinal tract, and dysbiosis. The presence of various manifestations of allergies also serves as a sufficient reason to take Vijaysar.
CardiASK is another well-known analogue of the Neurox drug. Instructions for use (analogues are also accompanied by such a document) regulates the drug as a good prophylactic against such formidable diseases as acute and repeated myocardial infarction. An unstable form of angina pectoris, prevention of stroke, thromboembolism (after surgical and invasive interventions on the vessels), deep vein thrombosis - all this is the reason for the medical specialist to prescribe the drug.
For the treatment of patients suffering from various kinds of abnormalities in the cerebral circulation, which can be expressed in a decrease in memory, attention, and deterioration of intellectual abilities, another analogue of Neurox is used - Ginkoum. Usually, medical specialists prefer to prescribe this drug as a component of complex therapy with a deterioration in blood microcirculation and peripheral circulation. Symptoms of such a disease are pain when walking, a feeling of coldness in the limbs, cramps of the calf muscles.In addition, this analogue drug is effective in worsening the functioning of the inner ear, which is expressed in impaired coordination, dizziness, and tinnitus. According to consumer reviews, Ginkoum is a worthy analogue of the Neurox drug, the price of which can range from 170 to 280 rubles per package.
Conclusion
That, perhaps, is all that can be said about the Neurox drug. Reviews, price, effect of the application, indications and contraindications - all this was described in detail in the review.
( !), . , «», , .