If the baby has an intestinal disorder, which is accompanied by diarrhea and deterioration of well-being, the drug “Phthalazole” is often prescribed - an effective medication that can quickly eliminate diarrhea and prevent the undesirable effects of toxicoinfection, colitis, dysentery and other negative conditions. Next, consider how to give Phthalazole to a child.
The pharmaceutical market has a wide variety of effective medicines, but it’s the “Phthalazole” for diarrhea for children that has been recognized by several generations of people, due to its low cost, the ability to purchase this product in any pharmacy, the absence of harmful chemical compounds and a long shelf life.
Pharmacological properties
It is necessary to consider in detail the instruction to "Phthalazole" for children. The drug belongs to the category of sulfonamides, which act exclusively on the digestive tract (rectum, intestines) and have minimal properties absorbed into the bloodstream. This medication does not accumulate in the tissues and is excreted from the body through feces.
The active active element of the drug is able to integrate into the process of folic acid production, which is necessary for pathogenic microorganisms for life and reproduction. The main substance of this medicine is phthalyl sulfathiazole, which is active in the destruction of gram-positive and gram-negative microbes, including pathogens of various intestinal infectious pathologies. Poorly absorbed from the digestive tract and exerts its effect mainly in the lumen of the intestine, where there is a gradual release of sulfonamide parts of its molecules.
The basis in this case is competitive antagonism with PABA and competitive inhibition of dihydropteroate synthetase. This contributes to a disruption in the production of tetrahydrofolic acid, which is necessary for the synthesis of pyrimidines and purines.
In order to ensure the destruction of all pathogenic bacteria in the intestines of the child, experts recommend giving him the “Phthalazole” medication for 5-7 days, since the action of active elements only affects microbial cells at the propagation stage, without affecting those that are in the usual state of
The medication also has an anti-inflammatory effect on the body, prevents an increase in the level of leukocytes in the area affected by pathogenic microorganisms.
Many parents ask if the Phthalazole children can?
Structure
Phthalylsulfathiazole - the main substance of this pharmacological preparation, is exposed to enzymes and at the same time breaks down into the amino group, sulfathiazole molecules and phthalic acid. Talc, potato starch and calcium stearate are additional components of the medicine.
Release form, storage
Phthalazole medication is produced only in tablet form; children's pharmaceutical form (syrup, gel, drops) is not produced by Russian pharmaceutical companies. The shelf life of this medicine must be counted from the release date - it is 5 years. This product is stored in a dry place at a temperature of no more than + 25 ° C. If the package is damaged, as well as improper storage or after the expiration of the storage period, it is not recommended to use the medication, due to its low effectiveness or lack of therapeutic effect.
Tablets are dispensed without a prescription, however, before using this pharmacological agent for the treatment of diarrhea in childhood, it is advisable to consult a specialist. For children under the age of 3 years, the pediatrician will recommend a similar drug with fewer contraindications and adverse reactions.
Indications for use
When is Phthalazole prescribed for a child?
A medical tool in children is used in the development of the following pathological conditions:
- dysentery;
- enterocolitis;
- ulcerative and ulcerative necrotic colitis;
- infectious gastroenteritis;
- dysbiosis;
- infectious inflammatory processes in certain sections of the intestine;
- unwanted complications after surgical and diagnostic procedures;
- foodborne toxicosis;
- salmonellosis;
- diarrhea of various etiologies.
With the development of diarrhea in a child, the antidiarrheal effect is noted for 2-3 days from the start of the use of a drug that inhibits pathogenic microflora, helps to normalize water-salt metabolism and general digestive system indicators. The use of a medication in some cases is prescribed before surgical interventions on the intestine, which helps prevent the negative consequences of an infectious and inflammatory nature. Is Phthalazole always allowed for a child?
Contraindications
This medication has certain contraindications, therefore, before giving a child these pills, it is necessary to consult a pediatrician and carefully study the attached instructions. The medication is not allowed for children to take if they have one or more pathological conditions:
- intestinal bleeding;
- the presence of intestinal obstruction or suspicion of it;
- severe pathologies of the liver and kidneys, which is accompanied by a violation of the functionality of these organs;
- individual intolerance of elements from the composition of the drug.
Another contraindication to the use of "Phthalazole" for a child is the age of 3 years, in which case the prescription of the drug is carried out exclusively by a specialist.
Side effects
When using a pharmacological agent in children, the following side effects may occur (according to the annotation from the manufacturer):
- headaches;
- dizziness, weakness, depression;
- myocarditis;
- changes in blood composition;
- dyspeptic symptoms - bouts of nausea, vomiting;
- swelling in the face;
- allergic reactions;
- skin rashes;
- fever;
- pneumonia.
In order to enhance antimicrobial efficacy, a medication can be used with simultaneous treatment with antibacterial agents.
This is confirmed by the instructions for "Phthalazole" for children.
Dosage and administration
The tablets are taken orally by swallowing whole, or after dividing at risk into 2 or 4 parts. Drink the drug is recommended a large volume of water. If the child cannot swallow the tablet, it is allowed to grind it to a powdery mass and dissolve in warm water.
The dosage of Phthalazole for children is determined taking into account the type of disease for the treatment of which it is used in a particular case, as well as the age of the child. Detailed information on the dosage regimen can be found in the instructions for the medication, but most often it is determined by the doctor.
When combating dysentery, no more than 50-70 tablets are allowed for the entire therapeutic course, which corresponds to 25-30 grams of the main active element. The maximum single dose for a child is 1000 mg, daily - 5000 mg. For children weighing up to 10 kg, daily doses should not exceed 3000 mg.
It is extremely important to adhere to the time intervals between taking the tablets of this medication. Night breaks of up to 8 hours are allowed. The average course of therapy with Phtalazole lasts about a week. When using a medication to treat diarrhea of unknown etiology, a signal to stop taking the drug is to stop the diarrhea in the child within 10 hours.
What else does the application instruction for Phthalazole for children tell us?
Drug interaction
It is allowed to combine this drug with antibiotics of different groups in order to enhance the antimicrobial effect. In addition, also with the aim of expanding the spectra of antimicrobial activity and enhancing the effect, Phthalazole can be given to children in combination with sulfanilamide drugs that are well absorbed into the bloodstream (for example, Sulfadimezin, Biseptol, Etazol).
Phthalazole tablets for children cannot be used in the treatment of diarrhea simultaneously with the following pharmacological agents:
- paraaminosalicylic acid agents - Anestezin, Novocain, Dikain;
- salicylates (Aspirin-Cardio, Aspirin);
- barbiturates (Phenobarbital, Pentobarbital, Penobarbital, etc.);
- "Diphenyl";
- nitrofurans (for example, "Furazolidone" and others);
- "Oxacillin";
- "Calcium chloride";
- "Thioacetasone";
- vitamin K;
- "Levomycetin";
- indirect anticoagulants (Thrombostop, Warfarin, etc.);
- "Hexamethylenetetramine."
Special recommendations
The experience of using this medication among children under 8 years of age is limited, however, if necessary, a specialist can prescribe these tablets to a child, calculating the dose individually, depending on body weight. The medicine does not adversely affect the central nervous system and the speed of psychomotor reactions.
So it is said in the instructions for the use of Phthalazole tablets for children.
Analogs
The medicine has many analogues on the pharmaceutical market, which include medicines with an identical spectrum of effects and therapeutic activity, containing an excellent basic substance. The following medicines are included in the list of Phthalazole analogues:
- Bactrim
- "Biseptolum";
- "Berlocide";
- "Brifesceptol";
- "Co-trimoxazole";
- "Dvaseptol";
- "Metosulfabol";
- Sinersul
- Oriprim;
- Sulotrim;
- Ftazin;
- "Sulgin";
- "Furazolidone."
Reviews
Almost all reviews of this pharmaceutical product are positive. Parents of children who have been treated with this drug indicate that the main disadvantages are the following qualities of the drug - the large size of the tablets, unpleasant taste, and in certain cases the need to take them for a long time to completely eliminate the symptoms of diarrhea in the child. Parents consider the advantages of the drug “Ftalazol” to be its high efficiency, moderate cost, lack of signs of addiction, as well as the ability to purchase literally in any pharmacy, which is very important in emergency situations. In addition, the long term of use is considered an advantage of the medication, which allows to confirm its safety and harmlessness.
Parents consider the rare occurrence of allergic reactions and side effects as well as the fact that the medicine works even when modern probiotics are powerless (Enterol, Bactisubtil) as another positive quality of Phthalazole.
Parents also note that the remedy is effective not only in the development of diarrhea in children, but also in case of symptoms of poisoning, with vomiting, nausea, excessive gas formation, etc. There is also information that this medication was used in the treatment of diarrhea in infants. However, in most cases they did not have side effects, the drug was well tolerated.
We reviewed the instructions for the use of "Phthalazole" for children. This will allow us to draw conclusions about the advisability of using the drug in a particular case.