Nausea and vomiting are very unpleasant phenomena that can be caused by various reasons. If the problems are related to poisoning, in no case should the process be stopped. Vomiting helps rid the body of toxins. It is important to restore water balance. If nausea is not associated with poisoning, the Motizhect tool will help get rid of it. Instructions for use describe in which cases you can use the drug.
Release form and composition
Motizhect is a central-action antiemetic drug, which is available in the form of tablets. The active ingredient is domperidone. Additionally, the composition of the drug includes substances such as lactose, potato starch, magnesium stearate, hydroxypropyl cellulose, colloidal silicon dioxide, povidone, polyethylene glycol, talc, titanium dioxide. The tablets go on sale in blisters.
The drug is characterized by a peripheral mechanism of action. The main component acts on the receptors responsible for the gag reflex. If vomiting is not caused by poisoning, Motizhect (tablets) can be used. Instructions for use indicate that the drug increases the duration of peristaltic contractions of the atral stomach. As a result, nausea stops.
Pharmacokinetics
If the medicine is taken orally on an empty stomach, it is absorbed quickly enough. In this case, the patient's condition improves almost instantly. After eating, you can also use Motizhect tablets. Instructions for use informs that in this case the bioavailability of the active ingredient is somewhat reduced.
Domperidone binds to blood proteins by 90%. The active ingredient easily penetrates into any body tissue. Metabolism occurs in the walls of the intestines and liver. Not more than 60% of the active ingredient is excreted through the intestine. The rest is excreted by the kidneys.
Indications and contraindications
When is it worth taking Motizhect tablets? Instructions for use indicate that the drug can be used for nausea and vomiting of various origins. The only exceptions are cases of poisoning, when vomiting is a normal reaction of the body and helps to remove toxins. Motizhect tablets help relieve nausea during radiation and chemical therapy. Also, the drug can be used in the postoperative period when vomiting occurs as a reaction to anesthesia.
Nausea and vomiting are the accompanying symptoms of many ailments associated with the work of the stomach. A gastroenterologist may also be prescribed the Motizhekt drug. Instructions and contraindications will be available at the first appointment with a specialist. Tablets can be prescribed for diseases such as dyskinesia, flatulence, atony of the stomach, cholangitis, cholecystitis.
The Motizhekt means has a number of contraindications. Instructions for use make it possible to understand that a medicine cannot be recommended for children under 5 years of age. The medicine is not used for mechanical gastric obstruction, gastric bleeding, prolactinoma. In rare cases, hypersensitivity to one of the ingredients of the drug may develop.
special instructions
Must be studied before using the drug "Motizhect" instructions for use. The description of the medicine says that it can not be used during the first trimester of pregnancy. Women with nausea and vomiting should consult a doctor. Often, such symptoms indicate pregnancy.
The medication is not prescribed for children under 5 years of age. Restrictions apply to older children, whose weight does not exceed 20 kg. If a child experiences nausea of an unknown genesis, parents should seek the help of a pediatrician. The specialist will be able to find out the cause of the poor patient's well-being and prescribe the appropriate treatment.
In case of impaired liver and kidney function, it is worth taking Motizhect tablets with caution. Instructions for use of the drug indicate that for patients with such problems, the dosage of the drug should be reduced.
Dosage
Children and adults are prescribed to take Motizhect tablets at a dosage of 10 mg (1 tablet) three times a day. It is advisable to use the drug an hour before meals. So you can quickly achieve the desired effect. With severe nausea, you can double the dosage. With renal failure, the frequency of doses decreases. The course of treatment depends on the condition of the patient and the form of the disease.
In case of an overdose, adverse reactions may develop. Most often they appear in the form of an allergy. The patient has rashes on the body, which are characterized by itching. This phenomenon does not require drug withdrawal. In this case, the doctor should review the dosage. If, after reducing the frequency of administration, unpleasant symptoms do not disappear, the specialist selects a substitute.
In rare cases, adverse reactions associated with the nervous system may develop. They appear in the form of dizziness, sleep disturbance, irritability. Symptoms such as dry mouth and thirst may also appear. These phenomena are only temporary and can be observed only at the beginning of therapy.
Drug interaction
The bioavailability of the main component is significantly reduced while taking medication with antacids. If there is a need to use anticholinergics, it is worth remembering that they inhibit the action of domperidone. The combination of drugs will lead to the fact that nausea will only intensify.
The use of certain antifungal drugs can lead to an increase in the concentration of domperidone in blood plasma.
Patients who have chronic ailments and are forced to constantly take any medications should notify the doctor. The specialist will conduct a thorough analysis and conclude that it is advisable to prescribe Motizhect tablets in a particular case.
Analogs
What should I do if I could not find the necessary medication in the pharmacy kiosk? How to replace Motizhect tablets? Instructions for use, reviews, prices for them - all this information is studied by the patient before starting therapy. There are many drugs that have a similar composition. The most popular antiemetic drugs will be described below.
For adults and children over 5 years old, experts often prescribe the drug Motilium. A domperidone-based medicine can help with nausea and vomiting. Do not use the medication during gestation and lactation. With caution, tablets are used for renal failure. The dosage is determined by the doctor, in accordance with the form of the disease, as well as the individual characteristics of the patient's body. For one package of medicine you have to pay about 300 rubles.
Passazhitks is another domperidone-based medicine that is prescribed for nausea and vomiting if these symptoms are not caused by poisoning. The medicine is also not used during pregnancy and lactation. For one package you will have to pay about 130 rubles.
It is also possible to replace the Motizhect drug with Motilak, Domperidon-Teva, and Motonoyum tablets.
What do patients say?
Reviews show that adverse reactions do not develop if the instructions for use have been studied before using the Motizhect drug. Price is another pill advantage. For one package of medicine you will have to pay about 150 rubles.
Patients claim that pills perfectly relieve nausea. A more tangible effect is observed if you take the drug on an empty stomach.