The drug 'Platifillin'. Instructions, indications, contraindications

Medication "Platifillin" refers to the group of m-anticholinergic drugs. The medicine is available in tablet form, in the form of a solution for injection, drops, suppositories.

The drug "Platifillin" instruction recommends for peptic ulcer of the duodenum and stomach, intestinal, biliary and renal colic, cholelithiasis, cholecystitis, pylorospasm. Indications also include bronchorrhea, arterial hypertension, angiotrophoneurosis, spasm of cerebral arteries. The medication "Platifillin" the instruction recommends for bronchial asthma for the prevention of laryngo-and bronchospasm. In combination with other means, the drug is used for angina pectoris. The medicine "Platifillin" is indicated for the expansion of the pupil during diagnostic measures in ophthalmology, with acute inflammatory eye diseases, injuries.

Strengthened antispasmodic effect have drugs "Platifillin" with "Papaverine," if used in combination. As a result of this effect, blood pressure decreases, vascular tone decreases, and smooth muscles of the internal organs (urogenital, digestive and respiratory systems) relax.

The tool "Platifillin" the instruction does not recommend for acute bleeding, mitral stenosis, coronary heart disease, heart failure (chronic), tachycardia, atrial fibrillation, hypertension and other pathologies of the cardiovascular system, against which increased heart rate reduction may be an undesirable consequence. Contraindications include thyrotoxicosis, diseases of the digestive system complicated by obstruction (pyloric stenosis and achalasia), reflux esophagitis and a hiatal hernia combined with it, elevated temperature. The drug "Platifillin" the instruction does not recommend in case of hypersensitivity, pathologies complicated by high intraocular pressure, with intestinal atony in debilitated or elderly patients, open-angle glaucoma. The medicine is not prescribed to patients after forty years (long), with ulcerative colitis, liver failure, myasthenia gravis. The drug is not recommended for dry mouth, chronic pulmonary pathologies (especially in debilitated patients and young children), autonomic neuropathy. Contraindications include prostate hypertrophy without obstructive lesions of the urinary tract, the presence of urinary retention and predisposition to it, brain injury and central paralysis in children, preeclampsia, and Down's disease.

The drug "Platifillin" is not recommended during pregnancy. In the first trimester, the use is prohibited. In subsequent periods - only on the recommendation and under the supervision of a doctor. If a medicine is prescribed to a nursing woman, she should be warned about the need to stop lactation.

Among the side effects of the medicine, experts call convulsions, photophobia, headache, dizziness, intestinal atony, mydriasis. The use of the drug "Platifillin" can provoke a decrease in blood pressure, thirst, acute psychosis, urinary retention, lung atelectasis.

The introduction to eliminate pain of a spastic nature, a persistent attack of asthma, peripheral and cerebral angiospasm is carried out in a dosage of 1-2 milliliters (two percent solution). Injections are made once or twice a day. For infants and newborns, the dosage is 0.035 mg / kg, from one to five years - 0.03 mg / kg, from six to ten years - 0.025 mg / kg, from eleven to fourteen years - 0.02 mg per kilogram of body weight.

Inside, ten to fifteen drops of a solution of 0.5% are prescribed. Frequency of use - up to three times a day. In suppositories, it is recommended to use the drug "Platifillin" in a dose of 0.01 grams twice a day.

The therapeutic course is from ten to twenty days.


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