About the drug "Coraxan" reviews are various. Some patients note pronounced effectiveness of the drug. In others, taking the medicine caused only side effects. This suggests that all people have a different perception of a drug. In order to avoid the development of any unpleasant consequences, before using the medicine, it is necessary not only to study the annotation, but also consult a doctor.
The medicine "Coraxan" is available in the form of tablets, coated with a bright orange shell. The company logo is engraved on one side. The other side of the tablet contains the number "5" (the drug "Coraxan 5") or "7.5". The active ingredient is ivabradine hydrochloride.
Means "Coraxan" application instructions refers to the group of antianginal drugs. The mechanism of action of the drug is based on specific and selective inhibition of the channels that regulate the heart rate and diastolic depolarization (spontaneous).
The active substance of the drug does not have an effect on intracardiac conduction, ventricular repolarization, or contractility.
Medication "Koraksan" application instruction recommends for the treatment of stable angina pectoris with normal sinus rhythm in patients with contraindications or intolerance to beta-blockers.
The medicine is taken with food, inside.
As a rule, the initial dose of the drug is ten milligrams per day (per tablet (five milligrams) twice a day). In accordance with therapeutic efficacy, after three to four weeks of using the drug, a dose increase of up to 15 mg is allowed (7.5 mg per tablet twice a day).
With the development of symptoms of bradycardia (arterial hypotension, dizziness, fatigue) or with a decrease in the heart rate to less than fifty beats per minute, a lower dosage should be established. If, after adjustment, the indicators do not change, the drug is canceled.
For elderly patients (over seventy years), the prescription of the drug "Coraxan", the instructions for use recommend starting with a dosage of two and a half milligrams (half a tablet of five milligrams) twice a day. In accordance with the condition of the patient, a gradual increase in dose is possible in the future.
Taking the medicine may cause some negative reactions. Side effects of the drug "Coraxan" instructions for use include the phenomenon of changes in light perception (photopsy), bradycardia, atrioventricular block, extrasystole (supraventricular), palpitations. Probably also worsening of angina pectoris, development of ventricular tachycardia, myocardial infarction, atrial fibrillation. The use of the medication can provoke diarrhea, headache, constipation, muscle cramps, nausea, shortness of breath, eosinophilia, dizziness.
"Coraxan" is contraindicated in cases of sinoatrial blockade, acute heart attack, cardiogenic shock, heart rate less than sixty beats per minute at rest, severe liver failure. Do not prescribe medication for unstable angina, atrioventricular block in the third, second degree. The drug "Coraxan" is not recommended during pregnancy. If necessary, use the medicine during lactation, feeding is stopped.
The medication is ineffective in the prevention and treatment of cardiac arrhythmias. The effect of the drug decreases with tachyarrhythmia.
Not recommended for patients with atrial fibrillation and other arrhythmias associated with the activity of the sinus node.
Before prescribing the drug, it is necessary to examine the patient for heart failure (chronic course).