Tivikai is a second-generation integrase inhibitor and is used to treat HIV. Its main active ingredient, dolutegravir, is patented by ViiV Healthcare. It can bind an enzyme that catalyzes the incorporation of HIV into the chromosome of human cells. This tool is recommended both for patients who have not previously received therapy, and for those who have experience with HAART.
Where can I buy the drug “Tivikai” cheaper
The described drug is an effective tool in the fight against HIV infection. It is able to normalize the patient's condition, reduce the concentration of viral RNA in plasma and significantly reduce the risk of complications.
But the price for Tivikai tablets in Moscow is around 25,000 rubles. for packaging, and since this drug will have to be taken for a long enough time, then treatment with it can noticeably hit the patient’s pocket. In early 2017, the Indian company HETERO announced the launch of the reproduction of the generic Tivikai under the local name DOLUVIR . Starting generic sales in India is a lifeline for many HIV patients whose treatment regimens are outdated or have little effect. Now for those who want to buy Tivikai at a lower price, there is an opportunity to purchase it at - Website of an Indian drug provider.
Here you can buy generics - drugs manufactured under license and having the active substance identical to the branded drug. The low cost of a generic is due only to the fact that for its release the company did not need to spend money on development, research and an advertising company. All this, respectively, and makes it possible to make a profit at a much lower retail cost of drugs.
Application and dosage
Tivikai tablets are prescribed in combination with other drugs for the treatment of HIV-1 infection for both adult patients and children over 12 years old, with a body weight exceeding 40 kg.
The named drug is prescribed only by a specialist. It is taken regardless of food. The dose recommended for patients who do not have resistance to InI is 50 mg once a day. And for those who suspect or have documented it, 50 mg is divided into 2 doses.
If you have missed taking Tivikai tablets for any reason, you should take them as soon as possible, but on condition that at least four hours are left before the next dose. Otherwise, it is better to wait for the next reception time according to the existing schedule.
Contraindications
The reviews available on the Tivikay preparation describe this remedy as highly effective and having a high threshold of resistance. But the purpose of this tool has its limitations. So, tablets are not used in case of:
- hypersensitivity to their main active substance (dolutegravir) or to other components of the drug;
- the need for the use of drugs containing dofetilide;
- at the age of 12 years and body weight less than 40 kg.
The drug is used cautiously if the patient has a severe liver dysfunction.
Side effects
The undesirable effects that may occur during the administration of Tivikai tablets include the following:
- diarrhea
- nausea, often accompanied by vomiting;
- flatulence;
- abdominal pain (in the upper sections);
- headache;
- vivid dreams;
- insomnia
- Dizziness
- skin rash and itching;
- fatigue.
Since the use of dolutegravir can cause the development of opportunistic infections or other complications, the treatment with this drug should be carried out only under the strict supervision of a specialist who has experience in treating HIV.