Every home medicine cabinet should always have a universal drug that can cope with pain caused by various factors. One of these drugs is Upsarin Upsa, which will be discussed in the framework of this article.
Pharmacological properties
The medicine has a wide range of analgesic effects. The active substance is rapidly absorbed and evenly distributed in all body tissues. The maximum plasma concentration of acetylsalicylic acid is observed after 15-40 minutes after administration. Acetylsalicylic acid as a result of hydrolysis forms an active metabolite - salicylic acid. The bioavailability of the drug is directly proportional to the dose taken.
Acetylsalicylic acid is metabolized in the liver and excreted through the kidneys with urine in the form of glucuronic conjugates and salicylic acid. Acetylsalicylic acid is an anti-inflammatory drug with antipyretic and analgesic properties.
When ingested, the Upsarin Upsa tablets begin to hiss because of the released gas. The resulting buffer solution is better absorbed by the mucous membrane in the acidic environment of the stomach. Compared to classic tablets, the use of Upsarin Ups minimizes the likelihood of irritation of the walls of the stomach.
The drug is dispensed in pharmacies without a doctor’s prescription, but use the medicine with caution. If there are contraindications, taking this drug can cause serious health problems and aggravate the patient's condition.
The drug should be stored in a place protected from children, at a temperature not exceeding +25 degrees Celsius.
Dosage and administration
In order to understand how to take Upsarin Upsa, you must refer to the instructions that the manufacturer applies. Tablets are dissolved in water or juice in a volume of 100-200 ml. Before use, you must wait until the drug is completely dissolved in the liquid. The solution is taken orally after a meal. The maximum daily dose is 6 effervescent tablets, or 3 g of active ingredient. Specify the exact dosage in the instructions, "Upsarin Upsa" 500 mg contains acetylsalicylic acid in 1 tablet. At one time, it is recommended to take no more than one tablet, the subsequent dose can be repeated only after 4 hours. For the elderly, the daily dose is reduced to 4 tablets per day, a single dose in this case should not exceed 1 tablet. Dosage is given taking into account the absence of situations that can cause a number of side effects. In the presence of chronic diseases or other abnormalities, only the attending physician can prescribe the dosage of the drug.
Instructions for use "Uppsarin Upsa" allows for severe pain, taking two tablets at a time, subsequent administration is also possible only after 4 hours. The duration of treatment without the supervision of a specialist should not be more than 5 days if the drug is used as an anesthetic. The use of the drug as an antipyretic may last no more than three days.
Forms of release and composition of the drug "Upsarin Upsa"
The drug is available only in the form of effervescent tablets, which must be dissolved in water. The tablet itself is white, flat, at risk for dividing into 2 oral doses. When the tablet is dissolved, gas is released, which is why contact with water is accompanied by hissing and the formation of small bubbles. The tablets are placed in strips made of foil-coated polyethylene, 4 pieces for each adhesion. Those, in turn, are packed in a cardboard box. Inside you can find detailed instructions for the tablets "Uppsarin Upsa".
One tablet contains 500 mg of salicylic acid - this is the active substance of the drug. As auxiliary components, the following substances are part of the medicine:
- sodium bicarbonate;
- maltodextrin;
- anhydrous citric acid;
- crospovidone;
- anhydrous sodium citrate;
- aspartame;
- povidone;
- flavoring.
Auxiliary components are needed to give the necessary characteristics to the drug. They extend the shelf life, give the solution a pleasant taste and accelerate the dissolution of the drug in the liquid.
Indications for use
Let's try to figure out what Upsarin Upsa helps. The drug should be taken with moderate or mild pain syndromes: headache, migraine, toothache, muscle pain, joint pain. "Upsarin-Upsa" is indicated for use in cases of occurrence of alcohol withdrawal syndrome. The effect of the drug is to relieve the symptoms characteristic of a hangover. "Upsarin Upsa" is prescribed at elevated body temperature, which arose against the background of colds.
The medication is widely used for cardiovascular diseases. The drug inhibits the synthesis of thromboxane A2 in cells, this helps to slow the rate of blood clot formation. This property of the drug is used in a number of the following cases:
- painless form of myocardial ischemia;
- myocardial infarction;
- after prosthetics of the heart valve;
- aortoarteritis;
- Dressler's syndrome;
- acute thrombophlebitis;
- pulmonary infarction.
Contraindications
Compliance with the instructions for Upsarin Upsa (effervescent tablets) is mandatory. Serious side effects may occur in a patient without diagnosing contraindications. Reception is prohibited in the presence of hypersensitivity to the components of the drug.
The list of contraindications for taking the medicine is quite large. The instructions for effervescent tablets "Upsarin Upsa" indicate the following risk factors and limitations:
- aspirin asthma ;
- vitamin K deficiency;
- violations of the liver and kidneys;
- hemorrhagic diathesis;
- ulcerative lesions of the gastrointestinal tract;
- phenylketonuria;
- portal hypertension;
- heart failure;
- combination with oral anticoagulants;
- aortic aneurysm.
The drug is contraindicated in children under 15 years of age who have diseases caused by viruses or colds. A healthy child can take this medicine as an anesthetic, provided that its weight is at least 30 kg. In this case, the dosage should be strictly observed, otherwise Reye's syndrome may occur. Symptoms of this disease are: severe vomiting, inappropriate behavior, impaired consciousness.
Uncontrolled intake of the drug is prohibited for women in the 1st and 3rd trimester of pregnancy, as well as during lactation. Acetylsalicylic acid enters the blood plasma and is concentrated in all tissues, passing from the mother's body to the fetus. Before taking the medicine, be sure to consult your doctor. Elderly people should take the drug with caution, strictly following the instructions.
Side effects
Before using the medicine, carefully read the instructions. Upsarin Upsa tablets, like other drugs with a wide spectrum of action, can cause some side effects. The risk of their occurrence depends on the duration of the drug and dosages. Allergic reactions to the components of the drug can occur in the form of:
- rash
- Quincke's edema;
- bronchospasm;
- aspirin triad.
The digestive system may inadequately respond to the active substance of the drug, especially in cases of violation of the schedule of administration and dosage of the drug. From the gastrointestinal tract, the following side effects may occur:
- nausea;
- vomiting
- abdominal pain;
- diarrhea;
- loss of appetite.
If the color of the feces is dark, almost black, this may mean that bleeding has begun in the intestines or stomach. This happens extremely rarely, mainly such a side effect occurs in people with high blood pressure.
Violation of the immune system is manifested as follows: blood pressure decreases, asthma attacks, rhinitis, and nasal congestion may occur. In some cases, anaphylactic shock may occur.
The nervous system may respond to the drug with the following symptoms:
- dizziness;
- headache;
- confusion of consciousness;
- hearing impairment;
- noise in ears.
Instructions for use of effervescent tablets "Uppsarin Upsa" states: prolonged use of the drug can cause thrombocytopenia, leukopenia, hyperbilirubinemia or anemia. In some cases, impaired renal function is observed.
Overdose
In case of exceeding the daily dose of the drug, side effects may occur. A high concentration of acetylsalicylic acid can lead to severe dizziness, nausea, and visual and auditory dysfunction. From the respiratory system, a malfunction can be observed: breathing becomes heavy, arrhythmic. In severe cases, clouding of consciousness may be observed, there is a likelihood of a coma.
If the first signs of an overdose occur, immediately rinse the stomach. During this procedure, part of the drug that has not yet managed to get through the mucous membrane into the blood will be removed from the body.
After cleaning the stomach, it is necessary to take a sorbent - activated carbon, Polysorb or another alternative. In case of an overdose of the drug "Upsarin Upsa", you must consult a doctor without fail, especially if the patient is at risk for age or existing diseases.
Interaction with other substances
Before prescribing the drug, it is necessary not only to monitor for tolerability of the components of the drug, but also to clarify information about other forms of therapy that the patient is undergoing. If the simultaneous administration of different drugs, it is necessary to clarify their composition.
There are a number of restrictions on the use of other medicines, the list is contained in the instructions for Upsarin Upsa. The use of effervescent tablets is contraindicated with the following drugs:
- Anticoagulants. It is necessary to pay attention to signs of the presence of internal or external bleeding. Acetylsalicylic acid can cause bleeding in a patient undergoing thrombolytic therapy.
- Platelet Aggregation Inhibitors. The drug increases the risk of bleeding if used together with drugs such as Ticlopidine, Clopidogrel, etc.
- Nonsteroidal analgesics. Elevated levels of acetylsalicylic acid can cause gastrointestinal ulcers or bleeding.
- Systemic glucocorticoids. There is an increased risk of side effects from the gastrointestinal tract.
- "Digoxin". There is an increase in plasma concentration.
- Alcohol. Interaction can lead to indigestion, bleeding.
- "Methotrexate". Methotrexate is displaced from association with plasma proteins.
- Diabetes Remedies There is a decrease in blood sugar.
- Valproic acid. The displacement of valproic acid from the connection with plasma proteins.
- Antidepressants. Increased risk of gastrointestinal bleeding.
Do not take “Upsarin Upsa” simultaneously with drugs that reduce the effectiveness of therapy. These are: diuretics, angiotensin-converting enzyme inhibitors, uricosuric agents.
Precautionary measures
Before prescribing the drug, make sure that the patient does not take other drugs, which include acetylsalicylic acid. Otherwise, the body may receive an overdose, the risk of side effects will increase. With a long course of taking analgesics, a headache may occur, to remove which you will need another dose of the drug, which, in turn, will increase pain.
Long-term use of the drug can lead to kidney disease, the risk of analgesic nephropathy is high. In the presence of serious chronic diseases, it is necessary to monitor before prescribing the drug. Perhaps the medicine will aggravate the situation and provoke an exacerbation of the disease.
Self-administration of "Uppsarin Ups" is not recommended for elderly people and children with low body weight. The effect of the drug on the body will persist for several days, so it is necessary to warn the patient about the risk of bleeding, which due to the action of the drug will be difficult to stop. It should be avoided during pregnancy due to the increased risk of bleeding.
Do not take medicine at the same time as alcohol. Abundant internal bleeding may occur due to the negative effects of alcohol and drugs on the mucous membrane of the gastrointestinal tract, side effects are described in the instructions for use. Upsarin Upsa effervescent tablets in combination with alcohol can be dangerous for people suffering from liver diseases, kidneys, stomach ulcers or other gastrointestinal diseases.
Consumer Reviews
According to consumers, “Uppsarin Upsa” is a universal remedy that should be in everyone’s first-aid kit. Taking the drug is not only convenient, but also comfortable in terms of speed of action. Improvement is observed within 15-20 minutes after administration. According to reviews, "Uppsarin Upsa" tastes good. Some note that the medicine reminds them of mineral sparkling water. When consumed, a pleasant, slightly pronounced citrus aftertaste remains.
Side effects are quite rare. In special cases of individual intolerance or violation of the regimen of admission, signs of poor health, dizziness, nausea, and a malfunction of the gastrointestinal tract may occur.
An important factor, according to consumers, is that the drug does not cause drowsiness or distraction. It can be safely taken in any situation: at the wheel, at an important meeting, at school, etc.
The drug is actively used by consumers to relieve alcohol withdrawal symptoms. There is an improvement in general condition, headache and dizziness go away. The drug lowers blood pressure and has a general analgesic effect. In this case, it can be taken only 6-8 hours after taking alcohol. Otherwise, complications can occur, up to the formation of gastrointestinal bleeding.
Finally
Summing up, it can be noted that the drug "Uppsarin Upsa" has become a universal remedy for relieving pain of various kinds, as well as an antipyretic medicine. The action of the drug is faster than conventional tablets, and the solution is safer for the stomach. The affordable cost and effectiveness of the drug makes it very popular among consumers.