Cardiovascular diseases are the most dangerous and common ailments in modern society. Patients with a number of problems with the heart, blood pressure and blood vessels are well aware of such a drug as “Lisinopril”. The instructions for use attached to each package of the drug contain information that the drug belongs to the category of antihypertensive drugs. However, the scientific name of the class of a substance will not say anything to the average man, so we turn to its properties.
The drug "Lisinopril" - a description of the pharmacological properties
The action of the drug is based on its ability to dilate blood vessels, as well as reduce the load on the heart muscle - myocardium. In addition, Lisinopril tablets have a natriuretic and cardioprotective effect on the body. They release the drug in the form of tablets, which must be washed down with water. Their action begins in an hour, and by six o’clock the active substance reaches its maximum concentration. The effect remains during the day. To achieve a stable hypotensive effect, "Lisinopril" is prescribed in a course of several weeks. Taking pills requires constant monitoring of the patient's condition.
Side effects and contraindications
Among the conditions in which the drug "Lisinopril" is prohibited, the instructions for use call pregnancy and the period of breastfeeding. In addition, the drug is contraindicated in kidney disease, hypersensitivity to the components of the tablets, as well as children.
Side effects can be divided into three groups:
- frequent manifestations (migraine, nausea, dizziness, dry mouth, weakness and dry cough);
- medium frequency (diarrhea, abdominal pain, mental fatigue, tachycardia, rash, hypotension);
- rare (impaired hematopoietic function, impotence, confusion, liver, kidney dysfunction, mood swings, hyperkalemia, Quincke's edema, as an allergic reaction to "Lisinopril").
The instructions for use also describe such single manifestations of side effects as fever, weight loss, pulmonary hemorrhage and a number of other dangerous disorders.
Method of administration and dosage
Dosage is determined individually, based on body weight, age, as well as the work of the kidneys, liver and other organs, as well as the presence of a reaction to the drug "Lisinopril". Instructions for use contain an indication of the need for a single dose of the daily dose determined by the doctor. There are three dosages: initial, average or, as it is called, supportive and maximum.
The initial dosage is not more than 5 mg, and if there is evidence, the daily norm is reduced to 2.5 mg.
The average dosage of the drug varies from 5 mg to 20 at a time.
The maximum dose for a patient is 80 mg per day. Her appointment is permissible in exceptional cases, only after appropriate examination.
The medicine "Lisinopril" - a description of analogues
Like any medicinal product "Lisinopril" has its own analogues. These include “Lysigamma”, “Lizoril”, “Iramed”, “Diroton”, as well as other drugs containing vasodilating substances of the same group and class as lisinopril.
Special recommendations
Tablets "Lisinopril" should be taken with extreme caution in case of disruption of the internal organs. Especially this recommendation applies to patients with kidney and liver problems. The drug in the process of its action removes a huge amount of salt and liquid from the body. Before taking and during it should constantly replenish the loss.
In especially dangerous situations, the use of the drug is also possible for pregnant women. However, the patient or her relatives are informed in advance about the risk. Treatment is carried out only if there is a threat to the life of the expectant mother.