Kvamatel is a medicine for the treatment of peptic ulcer from the group of histamine nerve endings blockers. The drug is made in tablet form for oral administration. Each tablet is film-coated and contains twenty milligrams of the active trace element famotidine. The drug is packaged in blisters for fourteen pieces. The article will detail the instructions for using Kvamatel, analogues and prices. Patient drug reviews will also be provided.
Pharmacological properties
According to the instructions to "Kvamatel," the medication belongs to a group of histamine nerve endings blockers. Under the influence of an active microelement, the production of hydrochloric acid and the activity of pepsin are reduced.
Kvamatel has no effect on the promotion of products along the gastrointestinal tract, and also does not affect the exocrine ability of the pancreas.
After taking the pill inside, the pharmacological effect develops after sixty minutes, reaches its maximum mark after three hours and lasts up to twenty-four hours, which directly depends on the dosage taken.
Indications
According to the instructions, Kvamatel is recommended for patients with the following diseases and conditions:
- An ulcer of the stomach and duodenum (a chronic pathology that occurs with the formation of ulcerative lesions in the stomach, a tendency to progression and the formation of complications).
- Ulcerous formations on the mucous membranes of the digestive system.
- Inflammation of the duodenal bulb with ulcerative formations.
- Dyspepsia (a violation of the normal activity of the stomach, difficult and painful digestion).
- Reflux esophagitis (a chronic disease characterized by pathological reflux of the contents of the stomach into the esophagus).
- Repeated bleeding from the upper stomach and intestines.
Contraindications
Like any other medication, Kvamatel has a number of prohibitions on taking:
- Pregnancy.
- Lactation.
- Age to fourteen years.
- Increased sensitivity to drug substances.
- Lactose intolerance.
- Severe liver and kidney disease.
How to use
The rules of admission are described in detail in the instructions for use "Kvamatela". The price of the drug is not indicated in it. The medication must be taken orally. To eliminate exacerbation of a stomach ulcer or duodenal ulcer, one tablet is prescribed in the morning and evening hours.
The drug is consumed before meals. The duration of therapy depends on the severity of the disease. According to the instructions, it should be at least two months. If the prescribed dosage is small, then under the supervision of a doctor, it is increased to eight tablets per day.
For prophylactic purposes, to prevent recurrence of a duodenal ulcer, “Kvamatel” is prescribed one tablet at night. The duration of treatment should be at least thirty days.
To prevent the absorption of gastric juice during anesthesia, take two tablets in the evening on the eve of the operation and in the morning before surgery.
With reflux esophagitis, the patient is recommended to take one tablet in the morning and evening for a month and a half.
Can I take the drug during pregnancy?
There is no information regarding the safety of the influence of the main component of the tablets on the development of the future baby, therefore the drug is not recommended for use by pregnant women.
According to reviews and instructions, Kvamatel is forbidden to be used by nursing mothers, since the active ingredient can pass into breast milk. If necessary, treatment of the mother of the newborn needs to decide on the termination of breastfeeding.
Side effects
During the course of this drug in patients with increased sensitivity, some negative reactions may develop.
From the digestive system, vomiting, dry mouth, flatulence, diarrhea, pain in the stomach, loss of appetite, inflammation in the liver can occur.
The following negative conditions can be observed in the cardiovascular system:
- Lowering blood pressure.
- Violation of the functioning of the heart.
- Cardiac arrhythmia.
- Slow heart rate.
The following negative conditions may also occur:
- Leukopenia and thrombocytopenia (decrease in the number of leukocytes, platelets, agranulocytosis).
- Skin rashes.
- Urticaria (an allergic disease that is manifested by the formation of blisters on the surface of the skin and on the mucous membranes).
- Redness of certain areas of the skin.
- Irritation on the surface of the skin.
- Bronchospasm (a pathological condition that occurs when the smooth muscles of the bronchi are contracted and their lumen is reduced).
- Angioneurotic edema (an acute condition characterized by the rapid development of local edema of the mucous membrane, subcutaneous tissue and the skin itself).
- Drowsiness.
- Weakness.
- Dizziness.
- Depression (a mental disorder characterized by a decrease in mood and loss of ability to experience joy, impaired thinking).
- Increased prolactin hormone production.
- Gynecomastia (breast enlargement with hypertrophy of glands and adipose tissue).
- Violation of the menstrual cycle in women.
- Myalgia (an acquired disease that is characterized by pain in muscles of various nature).
Overdose
When ingested high doses of the drug or prolonged uncontrolled intake of the drug, a person has signs of poisoning:
- Nausea.
- Indomitable vomiting.
- Excitation.
- Irritability.
- Tremor of the limbs.
- Lowering blood pressure;
- Acute vascular insufficiency.
- Tachycardia (increased heart rate).
If such symptoms occur, drug therapy should be stopped, the stomach rinsed, and symptomatic treatment given.
Interaction with other drugs
When taking the medication together with Amoxicillin or other medicines that include clavulanic acid, there may be an increase in the absorption of the latter, which increases the likelihood of severe side effects and poisoning.
Enterosorbents in combination with Kvamatel reduce the absorption of the main trace element, which leads to a decrease in its pharmacological action.
When used together with drugs that suppress hematopoiesis in the bone marrow, the likelihood of neutropenia increases (lowered level of neutrophilic granulocytes in the general cellular composition of the blood to a level less than normal). This tells us the instructions to the "Kvamatel." The price of the drug will be provided below.
Features
Therapy using Kvamatel can lubricate the clinical picture of malignant neoplasms of the stomach and mask it under an ulcer, therefore self-medication is contraindicated.
Before treatment, the patient must undergo a thorough examination, including blood tests for tumor markers.
It is not recommended to abruptly discontinue therapy, since in this situation a person may experience withdrawal syndrome with an exacerbation of the clinical picture of the disease.
For people with liver disease, the daily dosage is determined by the doctor.
Positive dynamics to a large extent depend on diet. During therapy, do not take foods and drinks that irritate the mucous membranes of the digestive system.
During therapy, a person needs to refrain from driving a car or mechanisms that require increased attention. About this warns the instruction to "Kvamatel."
Analogs
Substitute drugs are:
- "Famonite."
- Ulfamide.
- "Ranitidine."
- "Gastrosidine".
- Nizatidine
- Cimetidine.
- "Famotidine."
- Lafutidin.
- "Roxatidine."
Let us consider in more detail some of the analogues from the above list.
"Ranitidine"
The drug belongs to the therapeutic group of histamine nerve endings blockers. The medication is used to reduce the acidity of the gastric juice in various diseases of the gastrointestinal tract.
The main active ingredient of the drug is ranitidine hydrochloride. Its concentration in one tablet can be one hundred fifty or three hundred milligrams.
The presence of products in the gastrointestinal tract does not affect the degree of absorption of the main trace element. It evenly spreads over all body tissues, from the blood it enters the mucous membrane of the stomach, where it has a therapeutic effect. It is excreted from the body with urine. "Ranitidine" penetrates the body of an unborn baby through the placenta, as well as into milk during lactation.
An active microelement blocks the specific histamine nerve endings of the parietal glandular cells of the gastric mucosa, which are responsible for the production of hydrochloric acid. The price of the drug is from 13 rubles per pack of 20 tablets.
"Gastrosidine"
The medication inhibits the production of hydrochloric acid. Reduces pepsin activity. Increases the protective mechanisms of the mucous membrane of the gastrointestinal tract. Increases the production of gastric mucus and the concentration of glycoproteins in it, activates the secretion of bicarbonate by the gastric mucosa.
In addition, "Gastrosidin" increases in it the endogenous synthesis of prostaglandins and the speed of recovery, with which the drug helps to heal the damaged gastric mucosa.
The effect of the drug occurs an hour after use and persists for a day after administration.
Reviews about the medication are mostly positive. "Gastrosidine" effectively reduces the increased acidity of the stomach and eliminates the unpleasant symptoms associated with it. The cost of the drug varies from 15 to 20 rubles.
As a drawback, patients note that "Gastrosidin" can not be bought at every pharmacy.
Ulfamide
The drug is actively used for stomach ulcers and duodenal ulcers. Ulfamide is available in tablet form. The drug relieves negative symptoms, allows you to get rid of heartburn. The main indication for taking the medication is the presence of dyspepsia.
"Ulfamide" is recommended for symptomatic and stressful ulcers of the stomach and intestines. The drug effectively eliminates reflux esophagitis, as well as polyendocrine adenomatosis. It is also used to prevent the prevention of bleeding. The cost of the medicine is from 53 to 74 rubles per pack of 20 tablets. This drug is also not sold in every pharmacy.
Storage conditions
Kvamatel can be bought at any pharmacy, but only by prescription. The drug must be stored at room temperature. So the instructions for use indicate. The price of Kvamatel is from 106 rubles per pack of 14 tablets.
Reviews
Basically, patients and doctors leave positive feedback about the drug, since it helps to quickly eliminate the negative symptoms of increased acidity of the gastric juice, if the treatment instructions follow the application of “Kvamatel”. In reviews of the price of the drug, it is reported that it is very low, and medication can be purchased at almost every pharmacy.
In exceptional situations, patients stop using Kvamatel. This is mainly due to side effects.
Most people take the drug with them on vacation to help the stomach cope with the excess load from the food they eat and not to suffer from complications of gastritis on vacation.
The drug is also effective in eliminating unpleasant symptoms when using medications that irritate the gastric mucosa.
Negative feedback about the Quamater is rare. They are usually left by patients who have experienced withdrawal symptoms. After a sharp cessation of the drug, the production of hydrochloric acid may become even greater than before the start of therapy. Therefore, do not throw sharply the reception of “Kvamatel”. You need to do this gradually, reducing the dosage to zero.
We reviewed the instructions for use "Kvamatela" and analogues. In the reviews about the price of all these drugs, it is noted that it is low, affordable for people with any material income. However, some drugs can only be found in online pharmacies.