How should I use the drug "Genferon" (spray)? Instructions for using the local remedy will be presented later. You will also learn about what is included in this medication, how much it costs, whether it has contraindications and side effects.
Composition, packaging, description
In what packaging is Genferon (spray) sold? Instructions for using this medication are enclosed in a cardboard box, where the dark glass bottle with a dispensing cap is located.
The agent in question is available in the form of a clear and clear liquid. The active ingredients of the local drug are recombinant human interferon alpha-2b, as well as taurine. In addition, the spray contains additional components such as sodium chloride, dextran 40,000, glycerol, disodium edetate dihydrate, sodium hydrogen phosphate dodecahydrate, potassium dihydrogen phosphate, water for injection, potassium chloride, methyl parahydroxybenzoate, polysorbate 80 and peppermint oil.
Pharmacological properties
What properties does Genferon have? Spray has the following effects:
- immunomodulating (there is a harmonization of the functions of the immune system);
- antivirus;
- antiproliferative (inhibits the growth of bacteria and cancer cells);
- mediated antimicrobial;
- immunostimulating (improves immunity);
- anti-inflammatory.
Mechanism of action
How does the drug "Genferon"? The spray, or rather, its active component, has an indirect effect on intracellular pathogens (chlamydia and other viruses), changing the metabolism and stopping cell replication, as well as preventing their further spread.
According to experts, interferon also affects neighboring cells, thereby initiating reactions that lead to inhibition of the production of viral proteins. The result of this effect is the death of the virus and blocking its further reproduction.
In addition, interferon is able to activate a number of genes that play a crucial role in the antiviral defense of the body, and also triggers the mechanism of destruction of infected cells.
Another direction of interferon is the activation of immunity. As a result of this effect, the cells of the immune system effectively fight various bacteria and viruses.
As for taurine, it improves the metabolism of both individual cells and tissues in general. Also, this substance stimulates regenerative processes, stabilizes and improves the structure of cell membranes.
Taurine is called an antioxidant. It interacts with active oxygen compounds, preventing tissue damage.
Pharmacokinetics of local drugs
What pharmacokinetic properties does Genferon (spray) have? Experts say that the intranasal use of this drug is characterized by a pronounced antiviral and immunostimulating effect. This effect is due to the high concentration of interferon in the pathological focus.
Due to the special molecular structure of the nasopharyngeal mucosa, the medication does not reach the bloodstream. Although a certain amount of the active ingredient still enters the bloodstream. This contributes to the immunomodulatory effect.
Indications for use
What is the purpose of prescribing the nasal preparation "Genferon"? The spray, the price of which is indicated below, is used for injection into the nasal passages in the following conditions:
- flu, a cold;
- acute respiratory infections (infections, viruses).
Contraindications
What contraindications does Genferon have? Spray (the price of this tool depends on the margin of the pharmacy network) in no case should be prescribed for:
- severe pathologies of the heart;
- the presence of allergies, as well as sensitivity to the ingredients of the drug;
- under the age of 14;
- epilepsy.
It should also be noted that people who suffer from regular nosebleeds should use the nasal preparation with extreme caution and under the strict supervision of specialists.
The drug "Genferon" (spray): instructions for use
How should i use nasal spray? This medication is used by introducing the tip of the bottle into the nasal cavity and one quick press on the dispenser.
When ARVI or influenza begins, the patient is prescribed one injection of the drug in both nasal passages. The frequency of use of the drug is three times a day, and the duration is 5 days.
In order to prevent influenza or SARS (for example, after contact with infected people), and also after hypothermia, the following scheme should be followed: one injection in both nasal passages twice a day for a week.
Stepwise Application Method
How is it necessary to inject Genferon? The spray is used as follows:
- remove the protective cap;
- repeatedly press on the dispenser until a not very large jet appears (only during first use);
- give the bottle with the drug a vertical position;
- administer the drug by single and quick pressure on the dispenser (alternately in both nasal passages);
- close the protective cap.
To avoid the spread of infection, the vial should be used only by one person.
Cases of overdose and side effects
Does Genferon Light cause unwanted effects? ” Spray (the price of this medicine is not very high) never causes any side effects.
It should also be noted that in the instructions attached to the medication, there is no information about cases of overdose with this drug.
Can Genferon be prescribed for children?
Spray with interferon is not recommended for use by children under 14 years of age. However, in some cases, drugs with such an active substance are still prescribed for newborns and premature babies with pneumonia, sepsis or meningitis.
At what dosage is Genferon prescribed for children? Spray for adolescents over 14 years of age is recommended to be used in the same dose as adults.
Pregnancy period
Is it possible to use Genferon (spray) during pregnancy? The use of the drug during gestation is possible. However, such a medication should be used only according to indications and strictly after consultation with the attending physician.
Analogs and cost
Do you know how much the Genferon Light nasal preparation (spray) costs? The price of this medication may be different, depending on the margin of the pharmacy network, as well as the place of residence of the patient (region). On average, the cost of this tool varies between 240-250 rubles.
As for analogues, the drug in question, intended for injection into the nasal cavity, can be replaced by the Nazoferon spray. There are also other means with other routes of administration. These include drops in the nose “Grippferon”, injections “Alfarekin” and ointment “Virogel”.
Reviews on nasal agent
Spray "Genferon Light" has an already established reputation. Patients respond about him on the positive side. Many people were able to prevent the development of acute viral infection by using the drug in prophylactic dosages.
Most often, reviews about this drug are left by parents of adolescents. They claim that after just a few injections of the spray, the condition of the children improves markedly.
In addition to the positive reviews on the nasal preparation "Genferon", there are also negative ones. As a rule, they are associated with the ineffectiveness of therapy. However, experts argue that the lack of effect with immunomodulating and antiviral treatment can be explained by the severe course of the disease, as well as the lack of an integrated approach.
By the way, some patients are unhappy with the price of this drug. They consider her overpriced.