The article describes what the instructions for use with Enam are, at what pressure this drug is prescribed, its composition and analogues are described.
Doctors always pay increased attention to the pathological processes that occur in the vessels and heart. The pharmaceutical market offers a wide selection of drugs that are used to eliminate problems in the vascular system, including those aimed at lowering blood pressure. This is due to the fact that pressure drops in the arteries can provoke serious changes and even lead to death.
One of the common drugs, whose action is aimed at eliminating pathologies of the cardiovascular system, is Enam. The drug is widely used in medical practice and is recognized by experts as an effective tool. Many people wonder at what pressure the drug should be taken, as well as the limitations for its purpose. Let's try to answer these questions.
Structure
According to the instructions for use, Enam is a new generation drug and is part of the group of ACE blockers. The drug is made in India and is included in the list of medicines permitted in our country.
Enam is available in the form of white tablets, round in shape, separated by notch. Enalapril maleate acts as an active component. In addition, the composition of the drug is supplemented with substances such as lactose, zinc stearate and maleic acid.
In the instructions for use, Enam ointment is not described, since the drug only releases in the form of tablets.
The drug is produced in different dosages, which makes the selection of the required amount as convenient as possible. In pharmacies, tablets of 2.5, 5, 10 and 20 mg of the active ingredient can be purchased. One package contains 20 Enam tablets and instructions for use.
The properties
When the drug enters the body, its effect lasts up to a day. The main property of the drug is antihypertensive. Under the influence of enalapril, the process of converting angiotensin of the first type to the second is blocked. In addition, the active component has a positive effect on reducing the resistance of peripheral vessels, as well as on increasing the level of bradycardin.
Enam allows you to normalize the pressure in the arteries, as well as reduce the intensity of left ventricular hypertrophy. Also, the drug reduces myocardial oxygen demand and prevents the development of hypoxia.
Taking pills does not affect lipid and carbohydrate metabolism. The maximum concentration of enalapril occurs in the third hour after taking the drug. The process of excretion of the components of the drug occurs through the kidneys.
Indications
As indicated by the instructions for use with Enam, the following pathological conditions are indications for its use:
- Arterial hypertension in any form, including essential and renovascular.
- In combination with other drugs in the treatment of heart failure.
- To prevent coronary ischemia, as well as heart failure in patients who have revealed a decrease in left ventricular performance.
You can not take the drug on your own, as its uncontrolled intake can lead to negative consequences from all organs and systems.
Contraindications
Each drug has a number of restrictions for admission, and Enam is no exception. According to the attached instructions, the drug is not recommended for use with the following pathologies:
- An allergic reaction to the components of the drug.
- Children under six years old.
- Marked fusion or narrowing of the cusps of the mitral valve.
- The period of gestation and breastfeeding.
- Low blood pressure.
- Lactase deficiency.
- Narrowing the aortic lumen.
This information is presented in the instructions for use with Enam.
Constant monitoring by a cardiologist during the treatment period will be required for the following diseases:
- Coronary artery disease.
- Heart or kidney failure.
- Imbalance of water and salts in the body.
- Pathological disturbance of the circulatory process.
- Stenosis of the arteries of the kidneys.
- The patient is over 65 years old.
The first dose of the drug is recommended by specialists in a hospital.
Instructions for use
Enam can be taken with or without food. The dosage is selected by the cardiologist taking into account the characteristics of the patient and the severity of his condition. The collected history and individual characteristics of the patient are taken into account.
Cardiologists do not recommend dividing the drug several times, but taking the entire daily norm at the same time. After the diagnosis is made, the doctor should describe in detail the regimen for taking the drug, and also determine the duration of the treatment. There is, however, a standard therapy regimen.
At the initial stage of treatment, Enam, according to the instructions for use, uses 5 mg. Further, the dosage can be increased or decreased depending on the reaction of the patient. Recommended dosages are 10-40 mg per day. This scheme is not compatible with drugs from the category of diuretics.
If the doctor prescribes diuretics for co-administration with Enam, the therapeutic regimen is as follows:
- High blood pressure in the arteries. The daily dosage is selected based on the patient's pressure indicators.
- Chronic heart failure. The initial dosage is 25 mg. During treatment, constant monitoring of blood pressure and regular visits to a cardiologist are carried out.
- Prevention of hypertension. If possible, diuretics should be discontinued and 2.5 mg of Enam should be used.
- Diseases of the kidney against diabetes. If the patient has an increased pressure in the arteries, a standard treatment regimen is prescribed. If there is no violation of blood pressure, the dosage is minimal and is 2.5-5 mg.
All of these dosages are recommended, the doctor should prescribe the correct treatment regimen.
Adverse reactions
There are a number of undesirable reactions that can cause the use of Enam:
- Respiratory system: shortness of breath, dry cough.
- Skin reactions: itching, urticaria, edema.
- Digestive system: nausea and vomiting, diarrhea and constipation, pancreatitis, pain, kidney failure, dry mouth.
- Nervous system: headache, dizziness, decreased performance, depression, sleep disturbance, increased nervous irritability, drowsiness, general malaise.
Such adverse reactions to Enam as impotence, decreased libido, and hair loss are much less common. These symptoms appear extremely rarely and depend on the individual reaction of the body to the components of the drug.
The Enam analogues are not indicated in the instructions for use, but they exist and are described below.
Analogs
Sometimes, for one reason or another, the patient should not take Enam. In this case, you can replace it with a drug similar in effect. There are a lot of similar medicines, so the transition to an analogue should be discussed with your doctor.
The following drugs are considered the most common Enam substitutes:
- Burlipril. It is made in Germany. Indications are similar to the original, but the list of contraindications is less.
- Renapril. Similar in composition, however, with higher efficiency and speed. The drug is contraindicated for use during pregnancy, breastfeeding and at the age of under 18 years.
- Enap. The Russian analogue of Enam. The list of indications for the drug is somewhat wider than that of the analogue. The composition is identical.
Reviews
Reviews about Enam are rather controversial. He helped one when other similar drugs were powerless. Enam is often prescribed for older people to normalize pressure after a myocardial infarction.
Some patients complain of a sharp decrease in pressure when taking the drug, even at the prescribed dosages. This condition leads to a significant deterioration in well-being.
Many people switch to taking drugs from other drugs and are satisfied, since this treatment virtually eliminates the adverse reactions that are indicated in the instructions for use. Reviews about Enam, of course, vary, but it is this drug that is chosen by most of our compatriots today, faced with the problem of high blood pressure.