In the article, we consider the instructions for use and price for the drug "Aldetsin". It is a hormonal medicine used in the presence of allergic or vasomotor rhinitis to relieve and eliminate the main symptoms and inflammation. This drug has contraindications, therefore, before using it, you need to familiarize yourself with the features of the application. Let's start by considering the composition of this medical product.
Structure
According to the instructions to Aldetsin, beclomethasone dipropionate acts as the main component. The medicine also includes sodium dihydrate, dispersed cellulose, glycerol, citric acid monohydrate, benzalkonium chloride and purified water.
Drug action
The anti-inflammatory properties of the drug are achieved by inhibiting chemotaxis, which slows down the development of allergies. The active component helps to increase mucociliary transport, reducing the number of mast cells in the area of the bronchial mucosa.
The medicine "Aldetsin" has a positive effect on the function of external respiration. This medicine helps to restore the patient's reactions to the effects of bronchodilators, due to which their frequency of use is reduced.
This product is characterized by low absorption. This medicine does not possess systemic activity. During use, the drug may enter the digestive system along with saliva. Against this background, its inactivation occurs immediately after passing through the liver. About seventy percent of the drug is excreted after 96 hours with feces, the remaining part of the substance leaves the body through the kidneys.
Release Forms
As the instructions indicate, "Aldetsin" is produced in the form of:
- A spray intended for irrigation of the nose.
- Aerosol for inhalation.
This drug looks like a white opaque liquid in which there are no foreign impurities. A single dose may contain 50 micrograms of beclomethasone.
Nasal spray "Aldetsin" is produced in cylinders. Each of them has a valve. One such bottle contains two hundred doses. The container is packaged in a cardboard box. The kit includes a nozzle that is designed for irrigation of the nose.
Next, we consider the indications and contraindications for the use of the drug in question.
Indications
According to the instructions to Aldetsin, there are not so many indications for this medication. So, the main indications for its use are:
- The presence of vasomotor and allergic rhinitis.
- Polyps in the nasal cavity.
- The patient has bronchial asthma.
Contraindications
Among the contraindications are worth noting:
- Pregnancy along with lactation, and in addition, hypersensitivity.
- The age of the patient is up to six years.
- The development of tuberculosis, and in addition, local and systemic infections.
- The presence of hemorrhagic diathesis in the patient.
- Recent injuries or surgical interventions in the nose.
- The presence of frequent nosebleeds.
With great caution, you can use this tool (after consulting a doctor) for those people who have had a heart attack, as well as those who have a history of glaucoma along with amoebiasis, ulceration of the nasal septum, hypothyroidism, or liver failure.
Mechanism of action
According to the instructions to Aldecin, beclomethasone in the drug is a hormonal corticosteroid that has antihistamine, as well as anti-inflammatory and immunosuppressive effects. It favors the inhibition of the release of inflammatory mediators in mast cells, thereby increasing the production of lipomodulin.
Against the background of taking this drug, the release of arachidonic acid is reduced, and at the same time, the synthesis of metabolic products is inhibited. As a result, a reduction in edema is achieved, secretion of glands in the nasal mucosa is reduced, and at the same time, mucociliary transport is also improved. After inhalation, the drug does not carry out mineralocorticoid activity and does not have a resorptive effect.
Mode of application
When using the container for the first time, it must be carefully prepared by performing calibration. In this case, it is necessary to press the nozzle at least four times in order to establish the correct dosage of the drug. For subsequent use, there is no need to repeat the procedure. Calibration may only be required if the spray has not been used for more than two weeks.
Drops in the nose "Aldetsin" can be used by adults, and in addition, by children, starting from six years. The irrigation procedure includes the following steps:
- Rinse your nose thoroughly.
- The head must be folded back, and then hold one of the nasal passages with your finger.
- A few drops are injected into the free passage. In this case, it is required to inhale deeply with the nose, and then exhale through the mouth.
- It is important not to touch the nasal septum during irrigation.
Inhalation aerosol is intended for the treatment of adults and children from twelve years old. Mouth irrigation occurs three times at 100 micrograms at a time. During the day, it is allowed to use no more than 1 milligram of the drug. As prescribed by the doctor, aerosol can be used to treat children aged six to twelve years. In this case, the dosage per day should not exceed 0.5 milligrams.
Side effects
Side effects may occur in the form of:
- Allergic reactions of a local nature.
- The appearance of nasopharyngeal infections with the addition of a fungus.
- The occurrence of irritation of the nasal mucosa.
- The appearance of rhinorrhea and nosebleeds.
- Adverse reactions in the form of sneezing, dryness and impaired sense of smell are possible.
- Increases in eye pressure along with impaired appetite and glaucoma.
- The development of dyspepsia in the form of nausea, vomiting and diarrhea.
- Headaches and dizziness.
- The development of hypertension and shortness of breath.
With prolonged use of aerosol and Aldetsin nasal spray, perforation of the septum may occur, and therefore the drug cannot be sprayed directly onto it.
Overdose
In case of an overdose, hypercorticism syndrome may be observed along with suppression of adrenal function. If undesirable symptoms occur, it is recommended to reduce the dosage. If overdose symptoms persist, the drug is canceled.
special instructions
This medication should not be sprayed onto the nasal septum. The effect of the medication in question with the intranasal method of use may not occur immediately (if you compare the drug with local vasoconstrictor drugs), but only after a few days. This drug is able to reduce immunity, therefore, cases of the attachment of various infections during its administration are not uncommon. In this regard, people with a reduced immune response must take this factor into account.
Drug interaction
By means of Phenobarbital, Phenytoin, Rifampicin and other microsomal oxidation inducers, the effectiveness of this drug can be reduced.
Estrogens, along with Methandrostenolone, Theophylline, and adrenostimulants, which are taken in parallel with the drug in question, enhance each other's effects. In particular, the effectiveness of adrenostimulants increases.
Reviews about the drug
In general, we can say that consumers are satisfied with this tool. The drug "Aldetsin" on the Internet receives mostly positive reviews. In particular, praise him for helping to combat allergic rhinitis. It is noted that this disease is eliminated in a few days. Thus, its main symptomatology completely disappears in just a couple of days. People write that the spray "Aldetsin" demonstrates a cumulative effect, thanks to this it is possible to significantly improve the state of health after a course of treatment.
With proper use, side effects are extremely rare. The most common of them is called infection of the nasal passage due to the presence of reduced immunity. In the instructions for use, the price of "Aldetsin" is not indicated.
The cost of the drug
The cost of this drug in domestic pharmacies is approximately two hundred rubles. It depends on the region.
Analogs of "Aldetsin
Analogues of this medication are drugs such as Beklata, Beklazona, Bekonase and Nazonex. Cheap substitutes include Beklomethasone along with Nasobek. The medical synonym for the drug in question is Beclomethasone.