In the article, we consider the instructions for use, price, reviews and analogues of the Ketoprofen preparation. It is a medicine belonging to the non-steroidal type of anti-inflammatory drugs. It is a derivative of propionic acid. It has an analgesic, antipyretic, anti-inflammatory effect. Used for symptomatic therapy of acute pain accompanying arthritis and other conditions associated with damage to tendons and ligaments. The drug allows you to stop the pain, relieve morning stiffness, swelling in the joints, increase their mobility.
Pharmacological effects
Drugs that are part of the NSAID group contribute to the suppression of the inflammatory process that accompanies pathology of the musculoskeletal system, relief of pain, and temperature reduction. Such a therapeutic effect is due to the ability of the drug to inhibit the synthesis of the enzyme, which is responsible for the production of prostaglandins.
Prostaglandins provoke the occurrence of swelling, pain at the site of localization of inflammation. When using the medication, their synthesis is stopped, thereby the patient’s condition is eased with a variety of diseases associated with damage to blood vessels, veins, joints.
This is confirmed by the instructions for use with Ketoprofen. We will consider the price and reviews below.
Pharmacological forms, composition
The manufacturer produces the drug in several pharmacological forms, such as:
- Ketoprofen gel. Instructions for use indicate that the concentration of the active component in it is 2.5%. The gel is colorless, transparent, may slightly opalescent. Each gram of gel contains 25 mg of ketoprofen and additional components.
- "Ketoprofen" in the form of an ointment, the concentration of the active component in which is 5%. The ointment has a slightly yellow tint, a homogeneous mass, a light lavender aroma. Each gram of ointment contains 50 mg of ketoprofen and auxiliary ingredients, including carbomer, ethanol, lavender oil and others.
Ketoprofen gel and ointment are intended exclusively for external use. Packed in tubes of aluminum, each of which contains 30 grams of substance. Additionally, the tube is packaged in a cardboard box.
- Instructions for use with Ketoprofen Retard tablets indicate that each contains 150 mg of Ketoprofen. They are packaged in a package of 20 pieces.
- Tableted Ketoprofen Forte. The tablet has a blue color, is covered with a film coating. Each tablet contains 100 mg of ketoprofen, as well as additional components. The drug is packaged in blisters, on each of which 20 tablets are placed. One blister is placed in a cardboard box.
- Capsule "Ketoprofen". Each capsule contains 50 mg of ketoprofen, as well as auxiliary components. Each cardboard package may contain 20 or 50 capsules placed on a blister.
- Ketoprofen solution. The solution is used for intramuscular or intravenous administration; it has no color, is transparent, and has a yellowish tint. Packed in glass ampoules, each of which contains 2 ml of solution. Each milliliter contains 50 mg of active ingredient and auxiliary ingredients. Ampoules are packed in a cardboard box. In each such box, 5 or 10 ampoules can be located.
- Ketoprofen in the form of suppositories for rectal administration. Each suppository contains 100 mg of ketoprofen and additional ingredients. They are packed in contour blisters, in a cardboard package contains 12 candles.
Indications for use
According to the instructions for use, "Ketoprofen" in any of its pharmacological forms can be used as part of the complex treatment of diseases of the musculoskeletal system, which are degenerative and inflammatory in nature. Use of the medicine is indicated:
- With ankylosing spondylitis, which is inherently ankylosing spondylitis.
- With gout, pseudogout.
- With tendonitis.
- With osteoarthritis.
- With bursitis, lumbago.
- With rheumatoid, gouty, psoriatic arthritis.
The Ketoprofen tablet and in the form of suppositories, which have an analgesic effect, are often recommended for the treatment of myalgia, pain in the spine, and neuralgia. It is also used for sports injuries that have no complications (with tendon ruptures, bruises, sprains, dislocations). In addition, it can be used as an element of the complex therapy of inflammation of the lymph nodes, lymphatic vessels, veins (periphlebitis, phlebitis, lymphadenitis).
Injection "Ketoprofen" can be prescribed as an additional medication in order to stop the pain syndrome accompanying neuralgia, myalgia, tendonitis, algodismenorea, radiculitis, otitis media, toothache and headache. It is also used to eliminate pain that is accompanied by inflammation that occurs after an injury or surgery. It helps to alleviate the patient’s condition with oncological diseases.
Ointment and gel forms are prescribed for rheumatic and non-rheumatic muscle pains, to relieve inflammation caused by trauma, post-traumatic edema, to increase the range of motion of the joint, eliminate its swelling and stiffness.
This is stated in the instructions for use with Ketoprofen.
Contraindications
The drug is contraindicated if the patient has an individual hypersensitivity to any of its components, with severe renal, cardiac, liver failure, during pregnancy and lactation. Do not use the injectable form in patients under 18 years of age, tableted in patients under 15 years of age, gel and ointment - up to 6 years.
Its use is not recommended in the presence of ulcerative-erosive lesions in the digestive tract, proctitis, gastric, as well as intestinal bleeding. The list of contraindications also includes impaired blood coagulation (hemophilia), polyposis of the paranasal sinuses and nose, bronchial asthma, intestinal inflammation, intolerance to acetylsalicylic acid.
Use with caution
Particular caution should be exercised when using "Ketoprofen" in patients with marked hypertension, diabetes mellitus, anemia, and alcoholism. If therapy with medication is necessary, then treatment should be carried out under the supervision of a physician. The ointment and gel forms of Ketoprofen should not be used for eczema, infected wounds, weeping dermatoses and other dermatological diseases.
Instructions for use with "Ketoprofen"
Gel and ointment forms can only be used externally. Patients from 12 years old should be applied about 3-5 cm of the drug up to three times a day. The medicine should be applied in a thin layer, after which it should be carefully rubbed into painful and inflamed areas.
Patients 6-12 years old should use up to 2 cm of the drug, the frequency of use - up to two times a day. Therapy without medical advice can last no more than 14 days.
Quite often, such forms are used during phonophoresis.
The price in the instructions for use with "Ketoprofen" is not indicated. We will give it below.
When using a tablet medication, the dosage should be selected by a specialist individually. Most often, therapy for adult patients begins with a minimum dose, which is 300 mg in total for three doses. At the same time, 300 mg is the maximum daily dose.
Suppositories are used in a dosage of up to 200 mg. The duration of therapy is determined by the doctor.
How to apply injections?
In accordance with the instructions for use with Ketoprofen, injections are intended to be administered intramuscularly or intravenously 100 mg of the substance once, if it is necessary to stop the pain syndrome or relieve chronic inflammation. Infusion of the drug should be carried out only in stationary conditions. The maximum allowable amount of drug per day is 200 mg. The course of therapy should not exceed 3 days, in the future it is recommended to transfer the patient to "Ketoprofen" in other dosage forms.
An injection drug can be combined with potent analgesics of narcotic origin. That is, its mixing with morphine is allowed, for example. After which the mixture is diluted using saline. Combined injections should be given every 8 hours.
Negative impact
Instructions for use and reviews of "Ketoprofen" confirm that the following adverse reactions may develop during therapy:
- Purple, thrombocytopenia, anemia, agranulocytosis.
- Menometrorrhagia.
- Hemoptysis.
- The development of adipose tissue necrosis, abscess, infiltrate at the injection point of the drug.
- Hematuria
- Interstitial nephritis.
- Impaired renal function.
- Peripheral puffiness.
- Arterial hypertension.
- Tachycardia.
- Conjunctivitis.
- Blurred vision.
- Change in taste.
- Noise in ears.
- Speech disorder.
- Disorientation.
- Hallucinations.
- Peripheral polyneuropathy.
- Migraine.
- Nightmares.
- Nervousness.
- Fatigue.
- Drowsiness
- Dizziness.
- Headache.
- Bleeding in the stomach or intestines.
- Exacerbation of Crohn's syndrome.
- The appearance of ulcerations in the gastrointestinal mucosa.
- Dry mouth.
- Abdominal pains.
- Dyspepsia.
- Anaphylactoid reactions.
- Angioneurotic edema.
- Bronchospasm.
- Dyspnea.
- Rhinitis.
- Skin reactions.
That is, "Ketoprofen" has a fairly extensive list of negative reactions, in connection with which its use is possible only as directed by the doctor. In this case, all medical recommendations should be strictly observed. This will prevent the occurrence of side effects or minimize their number and severity.
This is indicated in the instructions for use with Ketoprofen.
Price
On average, the cost of a tube of Ketoprofen gel is 70 rubles, tablets, depending on their dosage, 200 rubles, capsules 100 rubles, suppositories 150 rubles. It depends on the region and the pharmacy network.
Analogs
If replacement of the drug with a similar agent is required, then the specialist may recommend the use of one of the following medicines:
- Flamax Forte.
- Fastum Gel
- "Ketoprofen Werth."
- Ketoprofen Organics.
- Ketonal Uno.
- Ketonal.
- "Quick gel."
- "Artrum."
The choice of an analogue remains with the specialist, since each of these drugs has features and its own contraindications.
We will not consider in detail instructions for use with Ketoprofen analogues.
Reviews
Quite often, there are patient reviews about the use of the gel form of the drug. They celebrate its effectiveness, affordable price. The medicine allows you to quickly get rid of the painful sensations that accompany a variety of injuries of a domestic nature.
The Ketoprofen tablet and suppositories have also gained the trust of specialists and patients. The medication anesthetizes well in case of toothache, headache, diseases of the musculoskeletal system, after operations.
Perhaps the only drawback of this medication is an extensive list of negative effects that it can provoke. To prevent their development, the patient should start therapy only on the recommendation of a doctor.
We have reviewed the instructions for use, price, and analogues of the Ketoprofen preparation.