If the patient is diagnosed with gastric ulcer, then special drugs can not be dispensed with. Doctors often prescribe a medicine like Pariet, but most patients refuse to buy it as soon as they find out the price in the pharmacy.
Scope of application
The drug “Pariet” is aimed at treating stomach ulcers, it also reduces the acidity of its contents. The combined effect of these tablets allows you to quickly normalize the secretory activity of the stomach. As a result, acidity drops, and patients feel better. As a rule, already on the third day after the start of taking the “Pariet” remedy, the stomach cells begin to function normally, and the condition of the patients is facilitated.
Given the rather high cost, many are looking for drugs-analogues of Parieta, but many patients and doctors claim that it is he who is the most effective. It is this remedy that quickly relieves pain,
lowers acidity and gives a chance for recovery. The main thing is to remember that with an ulcer it is important not only to drink all the prescribed drugs, but also to follow the prescribed diet.
Mechanism of action
The effectiveness of the tablets "Pariet" is provided thanks to the main active ingredient - rabeprazole sodium. It is absorbed into the walls of the stomach and blocks a special enzyme, which is responsible for the secretion of hydrogen protons from cells into the cavity of this organ. Due to this, the production of hydrochloric acid is stopped. Its action begins already an hour after taking the pill, this is confirmed by the instructions for use in each box of the “Pariet” preparation.
Analogues of this tool, which contain the same active substance, have the same effect on the patient’s stomach. It is worth noting that rabeprazole sodium acts for 48 hours, and the maximum effect of its administration occurs somewhere after 4 hours. Recovery to the previous level of secretion after the end of taking the drug is observed after 2-3 days.
It is also worth noting that the drug “Pariet” adversely affects the bacterium Helicobacter pylori, which provokes inflammatory diseases of the walls of the stomach.
Analogs
Fortunately for many patients, pharmacists have also developed a cheap analogue of Pariet. The most affordable is Omeprazole. True, it has another active substance - omeprazole. But the indications for admission are similar:
peptic ulcer of the stomach and duodenum, diseases associated with the action of Helicobacter pylori, erosive lesions.
No less popular are other analogues of "Pariet". A gastroenterologist may advise changing this remedy to a more affordable option, but with the same active substance. Such drugs include Rabeprazole, Zulbeks, Razol, Razol-20, Rabizol, Barol 10, Barol 20, Veloz, Rabifin, Geerdin, Rabijem ”,“ Rabimak ”,“ Ontime ”,“ Noflux ”,“ Bereta ”,“ Hayrabesol ”. True, some of the drugs presented can be quite difficult to find in pharmacies.
Selection rules
But making a choice yourself is not worth it; it is better to consult with your doctor. After all, it is important to choose the right dosage, which will help exactly in your case, the doctor also takes into account all possible complications and contraindications for use, and focuses on excipients that are part of a particular drug.
It is also worth considering that some analogues of Pariet are available in a different dosage form. For example, the drug "Gerdin" is a powder for injection, "Barol" is a capsule. Also, when choosing, take into account the dosage of the active substance in the selected product and the number of tablets in the package. As a rule, they are available in 10 or 20 mg.
Trying to choose a medicine for yourself is not worth it. But by prior agreement with the doctor, you can choose an adequate replacement. For example, Rabeparzol or Zulbeks are the counterparts recognized for the Pariet drug. Reviews about them from patients are not bad. Indeed, in these preparations one and the same active substance.
Contraindications
It doesn’t matter which analogue of the “Pariet” medicine you choose, an instruction is attached to each of them, which you must familiarize yourself with. If the patient is sensitive to any of the components, then you will have to look for a replacement for the chosen remedy.
Also, it is not recommended to use drugs with the active substance rabeprazole for pregnant women and those who breastfeed the baby. To date, there is no reliable information on the safety of the use of this category of funds among such patients. Contraindication is also the age of 12 years.
Before you start taking this class of ulcer drugs, you need to make sure that there are no malignant tumors in the stomach or other part of the digestive tract.
Possible side effects
But even if the patient has no contraindications, problems with taking the pills can still occur. It doesn’t matter what kind of analogues you choose for the Pariet drug, the price of them also does not play a decisive role, digestion disorders, nausea, vomiting, and pain in the epigastric region can occur from each of the drugs .
Although their cost varies significantly. So, the price of the drug “Pariet” for 14 tablets of 10 mg each is about 1100-1300 rubles. In this case, the usual "Rabeprazole" will cost no more than 200, "Zulbeks" a little more than 400, "Hayrabesol" - about 300 rubles.
In addition, any of the agents with rabeprazole can cause headaches, dizziness, insomnia, or drowsiness. In some cases, the onset of depression and visual impairment were even noted.
In addition to the above reactions, taking drugs can lead to an inflammatory or infectious disease of the upper respiratory tract, in very rare cases, the onset of bronchitis or sinusitis was noted.
But allergic reactions, which are expressed by itching, rash, pain, excessive sweating, are quite common. Urinary tract infections, flu-like symptoms, chills, and fever are also noted.
Dosage and administration
Regardless of which particular Parieta analogues you decide to purchase, all preparations with the active substance rabeprazole sodium are prescribed according to the same scheme. So, tablets are drunk in the morning on an empty stomach. It is advisable to swallow them whole without crushing and chewing.
Patients with gastric ulcers with exacerbation of the disease are prescribed 20 mg per day. Drink them recommend at least 4 weeks. If, after such a course, healing, according to doctors, is insufficient, then treatment will need to be continued. Usually, a second course is prescribed for another 4 weeks.
For patients with a duodenal ulcer, the appointment depends on the course of the disease. The doctor may recommend taking 10 or 20 mg 1 time per day from morning to meal. Treatment will last at least 6 weeks, and if necessary, it can be continued for another period.
Gastroesophageal reflux disease is treated for 4-8 weeks. If necessary, the doctor may then prescribe supportive therapy, in which you will have to drink 10 or 20 mg of the drug with the active substance rabeprazole once a day.
But when Helicobacter pylori is detected, it will be necessary to select special schemes aimed at destroying this bacterium. Rabeprazole in this case is prescribed in a dosage of 20 mg, but it must be drunk with antibacterial agents. When prescribing, doctors, as a rule, are guided by the already developed treatment regimens.
In this case, the form of release of the drug is not important, it can be either tablets or Barol capsules. The instructions for each of them contain a detailed description of the schemes by which they must be drunk.
Features of the reception
If you have serious health problems, in which it is necessary not only to follow a strict diet, but also to use special drugs that suppress the formation of hydrochloric acid in the stomach, then you need to remember a number of rules. If the patient notices an increase in drowsiness, which may well be when taking this class of drugs, he needs to abandon driving vehicles and other activities that require concentration.
It is not recommended for pregnant and lactating women, peptic ulcer therapy for this category of patients should be prescribed only by a specialist, taking into account their situation. In addition, people with impaired liver function should be careful and carefully monitor the slightest changes in their condition.
Do not forget that rabeprazole reduces the plasma concentration of such an antifungal agent as ketoconazole and does not interact with liquid antacids designed to neutralize hydrochloric acid in the stomach.
Drugs "Rabelok" and "Geerdin"
It is not worth it to carry out the selection of a generic on your own, this should only be done after consulting a doctor. Only a specialist, knowing the composition of various drugs, can advise an adequate replacement. So, for example, the medicines “Rabelok” and “Gerdin” are an proton pump inhibitor, they have the same effect as the “Pariet” remedy. They lead to the fact that the formation of hydrochloric acid is blocked in the stomach. But the drugs "Rabelok" and "Gerdin" in Russia are sold only in the form of a lyophilisate used to prepare a solution that is administered intravenously.
This product is manufactured in India. Of course, the price set for the Rabelok preparation is high. One bottle costs an average of about 300-380 rubles.
Means "Geerdin" is significantly cheaper. But in many Russian pharmacies you can’t find it, only in some they offer to purchase it on order. At the same time, the compositions of Rabelok and Geerdin funds do not particularly differ. The instructions for the drugs indicate that these drugs are available in the form of a lyophilisate with 20 mg of the active substance.