For the treatment of various infectious diseases, antibiotics and antimicrobial agents are prescribed - drugs that act detrimental to the cell of the microorganism, destroying and killing it. A large number of such drugs have been developed, and recently, drugs that are effective in infections of various organs have been widely used.
And now antibiotics of a wide spectrum of action acting on various groups of bacteria are most often prescribed. Among these medicines, there is such a drug as Ciprolet.
Antibiotic or not, what is its effect, what properties does it possess? These questions are asked by patients who are prescribed drugs of this group. This medicine is manufactured by Dr Reddy's, an international pharmaceutical company that aims to produce new affordable and effective drugs.
Antimicrobial agents
Antimicrobial substances are represented by several groups. One of the most popular and widely used are fluoroquinolones, a striking representative of which is Tsiprolet. Antimicrobial agents are chemicals that successfully fight microorganisms by disrupting their cell growth and stopping their activity. There are no analogues of fluoroquinolones in nature: they have not yet been invented in terms of chemical structure, composition and origin of such antibiotics.
Fluoroquinolones
Fluoroquinolones are substances that destroy bacteria, preventing them from multiplying and growing. Antibiotics have the same effect. However, by definition: antibiotics are substances that are produced by microorganisms, the main effect of which is to inhibit and stop the growth and reproduction of pathogenic bacteria.
Antibiotics are highly selective: some microbes die immediately under their influence, while others do not react in any way to their presence. Only the bacteriostatic effect of antibiotics was revealed: they only stop the growth of microorganisms. Antibiotics are obtained only chemically. Is Ciprolet an antibiotic is not a significant problem, the healing it brings is important.
Is Ciprolet an antibiotic?
So is Ciprolet an antibiotic or not? There is no answer to this question. Although it is a chemical substance, it has the most pronounced bacteriostatic activity, it affects a wide variety of microbial agents. Surprisingly, this drug has been used for a long time. It was created in 2007 and still has not lost its relevance due to good antimicrobial activity, accessibility and a minimum of side effects.
In any field of medicine, Ciprolet is used. What group of antibiotics is represented by this drug, without which no first-aid kit can do? This medicinal substance belongs to the group of fluoroquinolones. This group, like all antibiotics, has a destructive effect on the bacterial cell. The active substance of Ciprolet and its analogues is ciprofloxacin, which, entering the bacterial organism, destroys the DNA enzyme, which stops the synthesis of cellular proteins and kills both adult microorganisms and those that are in the process of reproduction. Rarely observed resistance or resistance to the drug "Tsiprolet 500". Antibiotic or not, this is not so important. From how to correctly name it and to which group it belongs, its excellent therapeutic effect does not become less. Free penetration into the cell of a drug substance that does not stop either the enzymes or the bacterium itself, makes DNA synthesis impossible, the cell stops and stops dividing. And at the same time irreversible processes occur in the nucleus, cytoplasm and membrane: the microorganism dies.
What explains the popularity of this substance
Many patients use the drug "Tsiprolet." An antibiotic or not is of little interest to people. An excellent result, a minimum of side effects and a low cost of the drug are important.
Among its positive qualities, the following should be noted:
- the mechanism of its “blow” to bacteria is unique;
- the degree of activity is high;
- it is possible to treat a wide variety of infections caused by gram-positive, gram-negative, aerobes, anaerobes, mycoplasmas, chlamydia, mycobacteria;
- microbes are unstable to its action;
- good tolerance to patients;
- quickly creating the right concentration for treatment;
- the half-life makes it possible to use it twice a day;
- increased effects of other antibiotics when combined with Ciprolet;
- compatibility with many types of antimicrobial agents ;
- treating an infection of any organ or system;
- the possibility of treating children, pregnant and lactating mothers;
- effect in the treatment of one drug without supplementation with other antibiotics;
- excellent tolerance with a minimum of side effects.
Application. How and how much
Important when familiarizing yourself with the action of the drug "Tsiprolet" instructions for use. An antibiotic due to the long half-life and prolonged post-antibiotic effect is prescribed 2 times a day after 12 hours. In severe cases, it is possible to prescribe 3-4 times a day, both parenterally and orally. In severe infections, 500-750 mg is used twice a day, and in mild forms of infectious inflammation, 250 mg is used with the same frequency. The course of treatment is 7-10 days, and sometimes 14 days.
How to use eye drops
Eye drops are used for inflammatory and ulcerative lesions of various membranes of the eyeball. Drop 1-2 drops into the affected eye every 4-6 hours. And treatment of a serious infection requires installation every hour, and in some cases, for example, with a bacterial corneal ulcer even every 15 minutes with a gradual decrease in the number of injections.
"Step therapy"
In severe cases of infectious diseases, "step therapy" is used: first, intravenous administration of the drug is prescribed, and then, when the patient's condition is relieved, they switch to tablet forms.
A good effect can be achieved if you do not use the Tsiprolet solution, but tablets. Instructions for use indicate that the highest concentration in the blood is achieved using the drug on an empty stomach in the absence of side effects: nausea, vomiting, dyspeptic disorders.
When used
In all medical institutions in Russia, fluoroquinolones are included in the list of vital drugs. Along with tablets, solutions are widely used.
Instructions for use will tell you about all the diseases in which the drug is prescribed to the Ciprolet tool: the antibiotic acts on a number of different pathogenic microorganisms that affect the organs of the respiratory, digestive, urinary systems, skin and soft tissues, with osteomyelitis, meningitis, encephalitis, septic infections, abdominal infections, sexually transmitted diseases, inflammation of the oral cavity.
Do you treat toothache?
Some people use antibiotics for toothaches. Ciprolet helps only if the pain symptom is caused by an infection: pulpitis, gingivitis, periostitis, peridontitis. This is an incomplete list of diseases that can be treated and even achieve good results, quick recovery and reduce the degree of contamination of blood and other organs with pathogenic bacteria when using the medicine "Tsiprolet 500". An antibiotic or not - doctors do not think about this issue when they see how a seriously ill patient is recovering.
What are the side effects?
It doesn’t matter what “Ciprolet” is called - an antibiotic or not, but it has the same complications when used as this group of drugs. Special, pronounced side effects are not observed. The drug is generally well tolerated. In some cases, drowsiness or insomnia, depression or increased irritability, headaches, causeless fears, absent-mindedness are possible.
Nausea, vomiting, diarrhea, an unpleasant aftertaste in the mouth, loss of appetite - these are symptoms characteristic of treatment with any antibiotic.
From the side of the heart and blood vessels, a drop in blood pressure, heart rhythm disturbances, a feeling of heartbeat are possible.
The urinary system also responds to Cyprolet: polyuria, urinary retention, crystalluria, bleeding, glomerulonephritis.
The liver reacts with the onset of hepatitis, a decrease in the functional state: an increase in bilirubin, urea in the blood.
Allergic reactions can be in the form of a skin rash or even anaphylactic edema. But this can be prevented by a blood test: with an increased number of eosinophils, the drug is better to cancel. In the blood, there may also be erythremia, leukopenia, thrombocytopenia.
The list of side effects is great, but reading reviews of Dr Reddy's Ciprolet antibiotics, we can conclude that with proper use, the frequency of adverse symptoms is negligible - from 3% to 20%. And in only 2.5% of cases, the severity of reactions requires discontinuation of the drug.
Additional recommendations
When using fluoroquinolones, it is necessary to adhere to some rules:
- avoid prolonged exposure to the sun to exclude photosensitivity;
- to prevent the formation of kidney stones, drink plenty of fluids;
- carefully used for cerebrovascular accident, convulsive syndrome, epilepsy, atherosclerosis (severe forms);
- during treatment with “Tsiprolet” one should not engage in work related to increased concentration of attention;
- if the treatment is carried out on an outpatient basis, then constant monitoring by a doctor is necessary;
- mandatory use of antihistamines, pro and prebiotics.
Instructions for use indicate that the drug can not be used for children under 15 years old, pregnant, lactating. However, it was found that the harmful effect of its use does not exceed the positive therapeutic effect that ciprofloxacin exerts in the treatment of infections in these groups of patients.
Alcohol + "Tsiprolet"
The antibiotic Tsiprolet and alcohol are incompatible. You should not even drink beer if you are undergoing treatment with fluoroquinolones, because in any case, the liver suffers with antibiotic therapy (this is indicated in the instructions), and alcohol not only destroys hepatocytes, but also blocks the activity of ciprofloxacin. In some cases, a violation of the central nervous system is possible up to a coma. And with such a frivolous approach to treatment, recovery cannot occur.
Strengthening or weakening the action of Cyprolet
If, together with Ciprolet, drugs are used that lower the pH of the gastric juice, then the absorption of ciprofloxacin will decrease. The same thing happens when iron, magnesium, zinc, aluminum-containing preparations are used together.
Nonsteroidal anti-inflammatory drugs and Ciprolet increase the likelihood of convulsive activity.
"Tsiprolet" and "Cyclosporin" increase the adverse effect on the kidneys.
Ciprofloxacin potentiates the effect of Warfarin, and theophylline slows down the process of eliminating Ciprolet.
The drug goes well with taking other antibiotics: while the effect of each is enhanced.
Release Forms. Price
The drug is available in the form of tablets of 500, 250 mg, solutions for intravenous administration of 100 ml, which contain 200 mg of the active substance, and eye drops.
In any pharmacy without a prescription, you can buy Ciprolet-500 (antibiotic). Its price is affordable: eye drops cost only 60 rubles. 50-90 rubles is a solution for intravenous or intramuscular injection. Ciprolet manufactured by Dr Reddy's can be purchased in the following packaging: 10 tablets of 500 mg for 110-120 rubles, a blister of 250 mg for 50-60 rubles.
Based on the foregoing, the use of Ciprolet for the treatment of infections is extremely effective: with the right dosage, taking into account interactions with other drugs, and choosing the benefit or risk ratio, treatment with this drug is safe, affordable and effective.