With the onset of cold weather, many people begin to feel unwell and muscle weakness. Experts say that these are the first signs of a cold. If you do not take action, then in the future, a person manifests symptoms such as nasal congestion, sore throat, dizziness, headaches and fever.
To eliminate all signs of flu and colds, doctors recommend taking an analgesic immediately. “Rinza” is ideally suited as it. Instructions for use, reviews about this medicine, its features, release form and indications for admission will be considered in this article.
Description, shape, packaging and composition
You can buy the mentioned medication in a pharmacy in the following forms:
- Oral drug "Rinza" (tablets). Reviews report that this tool has a round and flat shape. The tablets are available in pink with white and dark pink spots. They have beveled edges and there is a dividing risk (on one side).
The active ingredients of this drug are: phenylephrine hydrochloride, paracetamol, caffeine and chlorphenamine maleate. The following components are used: colloidal silicon dioxide, sodium methyl parahydroxybenzoate, corn starch, sodium carboxymethyl starch, povidone, talc, crimson dye and magnesium stearate.
The drug in tablets goes on sale in blisters, which are placed in boxes of thick paper.
- Solution for oral administration "Rinza" (powder). Customer reviews report that such a medicine can be purchased in bags that are packed in cardboard boxes. The composition of the medicinal powder includes such components as paracetamol, phenylephrine hydrochloride, pheniramine maleate and caffeine. It also contains additional substances.
Drug properties
What are the properties of the drug we are considering? What do the medical reviews say about him? "Rinza" is an antipyretic and analgesic. Also, this drug is assigned anti-congestive, psychostimulating and antihistamine properties.
Pharmacodynamics
How does the Rinza drug work? The instruction (reviews about the medication are presented below) reports that this is a combined remedy. Its therapeutic effectiveness is associated with the combination of properties of each of the components. Let's consider them in more detail.
Paracetamol is able to have antipyretic and analgesic effects. It eliminates pain in the back, head, throat and joints, as well as general discomfort that occurs with colds. In addition, this component effectively reduces the patient’s body temperature.
It should be noted that paracetamol inhibits the COX 1 and 2 enzymes. It reduces the synthesis of prostaglandins, and also affects the thermoregulatory center of the nervous system.
Unlike many non-steroidal anti-inflammatory drugs, the substance does not affect the mucous membranes of the digestive tract. Moreover, in therapeutic dosages, paracetamol does not affect water-mineral and other types of metabolism.
What role does phenylephrine in Rinza play? Reviews of doctors report that this substance belongs to alpha-adrenergic agonists. It helps to reduce the lumen of blood vessels, as a result of which hyperemia and swelling of the mucous membranes of the nose, nasopharynx and sinuses are eliminated.
Chlorphenamine has an antiallergic effect. It is a histamine receptor blocker. This component is able to reduce swelling and hyperemia of the mucous membranes of the nose, sinuses and nasopharynx, as well as weaken exudative manifestations.
As for caffeine, it is no secret to anyone that it has an exciting effect on the nervous system. The mentioned ingredient reduces drowsiness and fatigue, helps to increase physical and mental performance.
It should also be noted that caffeine accelerates and enhances the analgesic and anti-inflammatory effects of paracetamol.
Kinetic indicators
What kinetic properties does the medicine “Rinza” have? Customer reviews will not be able to answer this question. You will find it in the attached instructions. According to her, paracetamol is rapidly absorbed by the digestive system.
This substance is actively associated with plasma proteins. Its highest concentration in the blood is noted 60 minutes after administration.
We can not say that paracetamol penetrates well through the placenta and the blood-brain barrier.
Indications for use
What diseases are most effective for the remedy we are considering? What do the reviews say about this? “Rinza” is actively used by patients in the autumn-winter time, when there is a great chance to catch a catarrhal disease, which is accompanied by fever and nasal congestion.
After taking one tablet or one bag of powder, the patient immediately feels noticeable relief. This tool quickly relieves toothache and headache, as well as pain in the muscles and joints, with neuralgia, injuries and burns.
In addition to these conditions, the drug in question is indicated for use in acute rhinitis (including allergic), pharyngitis and sinusitis.
Contraindications
Under what conditions should not take the drug "Rinza"? Customer reviews report that their condition noticeably worsens if the medication was used if:
- hypersensitivity to the components of the drug;
- severe forms of atherosclerosis of the vessels of the heart;
- pyloroduodenal obstruction;
- severe hypertension;
- bronchial asthma;
- severe forms of heart failure, including cardiac arrhythmias;
- Dubin-Johnson syndrome;
- severe forms of hepatic and renal failure;
- pheochromocytomas;
- congenital increase in bilirubin in the blood;
- diabetes mellitus;
- chronic obstructive pulmonary disease;
- insomnia
- hyperthyroidism;
- alcohol addiction;
- blood diseases;
- glaucoma and increased intraocular pressure;
- a decrease in the number of white blood cells in the blood and hemoglobin;
- prostate hyperplasia with difficulty urinating;
- under the age of 15 years;
- epilepsy and convulsive conditions;
- pregnancy and lactation;
- hypersensitivity to xanthine derivatives ("Theophylline", "Theobromine").
It should also be noted that this drug should not be used simultaneously with beta-blockers, antidepressants and monoamine oxidase inhibitors.
The drug "Rinza": instructions for use
Tablets, the reviews of which are more positive, are prescribed for the same indications as the medicinal powder intended for the preparation of an oral solution. However, the methods of their use are significantly different.
Adults and children over 15 years of age, Rinza tablets are prescribed one at a time every 6-8 hours. Such therapy is carried out for no more than five consecutive days.
It is advisable to take the drug 90 minutes after eating. Drink the medicine with plain water. The maximum dosage of the drug is four tablets per day.
Now you know how to take Rinza (tablets). Reviews of experts say that this form of the drug is less preferred by patients. Most often, they acquire the drug in the form of a powder. According to consumers, such a medicine is more convenient to use and tastes good.
Powder Application Method
To make the Rinza drug solution, the contents of one sachet must be poured into a 250 mg beaker and poured with hot water. After thoroughly mixing the components, you should wait until the medication is completely dissolved. After that, it must be taken in small sips.
To obtain a therapeutic result, Rinza powder must be used three times a day. Treatment with this tool should be carried out no more than five days in a row.
If after taking the drug in question the patient's condition has not improved, then you need to see a doctor.
Side effects
What side effects does the drug we are considering cause? What do the reviews say about this? Rinza is well tolerated by patients. Side effects on the background of its intake are very rare. As a rule, undesirable reactions occur with long-term use of the medication, as well as when its doses are exceeded.
According to the instructions, this tool can cause the following side effects:
- heartburn, stool retention, pain in the stomach, increased activity of liver enzymes, loose stools, increased salivation, vomiting, poor appetite, impaired liver function, nausea, hepatonecrosis;
- bradycardia, heart palpitations, rhythm disturbance, heart pain, shortness of breath;
- hypoglycemia;
- feeling of anxiety, irritability, weakness, headaches, dyskinesia, increased irritability, depression, insomnia, convulsive states, tinnitus, coma;
- hallucinations;
- increase in blood pressure;
- anemia (including aplastic and hemolytic), thrombocytopenia, pancytopenia, agranulocytosis, neutropenia, leukopenia;
- nephritis, renal colic, dysuria, difficulty urinating;
- bronchospasm in people with allergies to NSAIDs and aspirin;
- dry eyes, impaired accommodation, dilated pupils, increased intraocular pressure;
- urticaria, skin rash, Stevens-Johnson syndrome, pruritus, toxic epidermal necrolysis, Quincke edema, anaphylactic shock.
Drug overdose
Paracetamol is able to have a toxic effect on the human body after taking a dose of 10-15 g. In this case, the following symptoms occur:
- a decrease in the value of prothrombin, an increase in the level of bilirubin;
- lack of appetite, pallor of the skin, nausea, discomfort in the stomach, diarrhea;
- weakness, pain in the right hypochondrium, sweating, hepatomegaly, jaundice, increased activity of liver enzymes;
- hepatonecrosis, hypoglycemia, metabolic acidosis, rhythm disturbance, coma, convulsive state, cerebral edema, collapse.
With an overdose of phenylephrine, there are: nervousness, confusion, dizziness, tremor of the extremities, arrhythmia, anxiety.
Signs of an overdose of chlorfenmin: intestinal atony, hypotension, dilated pupils, dry mouth, photophobia, hyperthermia, bradycardia.
Symptoms of an overdose of caffeine: headache, tremor, irritability, the appearance of extrasystoles.
To eliminate such conditions, gastric lavage, sorbent intake and symptomatic therapy are required.
Consumer and medical reviews
Rinza is a very effective and effective drug. This is the opinion most doctors adhere to. They prescribe this medication at the first symptoms of the flu and the common cold.
As for patients, they also argue that this tool is very effective in coping with the task. After several doses of the drug (in the form of tablets or powder), their condition improves markedly: body temperature decreases, nasal congestion is eliminated, muscle weakness and joint pain go away.
The main advantage of the medication in question is that it can be purchased at any pharmacy at a very reasonable price.