One of the most reliable cough medicine is Tos May. Instructions for use allow it to be given to children from the age of two. The drug is well tolerated and very rarely causes negative consequences.
Composition and packaging
The Tos-May preparation contains 2 mg dextromethorphan hydrobromide , 0.2 mg benzocaine, 15 mg sodium benzoate, and 35 mg potassium guaiacol sulfonate. Additional substances are: mannitol (E421), menthol, povidone, sodium saccharin, anise essence, talc, magnesium stearate.
The tablets are white and hard blotches. Enclosed in a blister of eight pieces. The package contains 8 or 16 Tos-May tablets, instructions for use.
The medicine belongs to the antitussive group and to the examiners. Has the ATC code R05F B. It is dispensed in pharmacies without a prescription.
Pharmacological properties of the drug
The Tos-May preparation has confirmed its effective effect on the body many times. The instruction for use gives it mucolytic, expectorant and antitussive properties.
Dextromethorphan as part of a medicinal product has an effect on the central point of manifestation of cough in the medulla oblongata, increasing the antitussive period. It also affects the peripheral chain of the cough reflex by inhibition of arising afferent impulses entering together with the mucous membrane of the respiratory tract. It does not have a narcotic and analgesic effect. The antitussive function is similar to codeine, but not addictive, unlike the latter. Does not inhibit the work of the respiratory center and the action of the ciliary epithelium of the respiratory system.
Benzocaine is an effective topical local anesthetic. Does not cause resorptive effects on the body. When using this substance in combination with other components, the brightness of the pain syndrome, which often appears with a strong dry cough, decreases.
Potassium guaiacol sulfonate has a pronounced expectorant effect. It activates the secretion of elements of bronchial mucus with a low proportion of viscosity. Hydrolyzes mucopolysaccharides and increases the effect of cilia of ciliated epithelial tissue of the respiratory tract. Reduces the upper tension and adhesive properties of the removed sputum, making its viscosity lower. Promotes the release of mucus from the organs of the upper respiratory tract. It has low antiseptic and anesthetic qualities.
Sodium benzoate is a direct mucolytic substance. When used orally, it increases the secretion of the glands of the bronchi, dilutes sputum, removes it from the respiratory tract. Endowed with a slight antibacterial and antifungal effect.
Pharmacokinetics of the drug
Tos-May tablets (the instruction fully describes all the intricacies of their use) are highly active and are rapidly absorbed into the walls of the digestive tract. Antitussive properties appear 15-30 minutes after taking the pill inside. Valid for 5-6 hours. The highest concentration of the drug in the blood is observed after two hours.
After two hours, the concentration of dextromethorphan in the blood serum reaches a maximum. It is rapidly metabolized in the liver. The half-life is six hours. It is excreted mainly by the kidneys. The main part comes in the form of residual metabolites, and a small dose - in the previous unchanged form.
Potassium guaiacol sulfonate is instantly absorbed by the digestive tract. After taking the pill, the highest concentration of the active component in the blood occurs after a couple of hours. The therapeutic effect lasts for six hours. The half-life is 2 hours. It is excreted in sputum and excreted from the body with urine in the form of metabolite products and partially in unchanged form.
Indications for use of medicine
Tos-May tablets (instructions for use should be read before treatment) are recommended for use in symptomatic dry irritating mucous coughs, which often occurs during the period of illness with influenza and SARS. It can be observed in acute tracheitis, bronchitis of varying severity, laryngitis and whooping cough. The drug is also used during the complex treatment of pneumonia, pleurisy, tuberculosis. Doctors prescribe a medicine before preparing the patient for bronchoscopy.
Contraindications
A good result is the treatment with the Tos-May drug. Tablets (the instruction draws attention to contraindications and side effects of the drug), despite their effectiveness, you can not drink with hypersensitivity to dextromethorphan and other ingredients that make up the medication. A ban on use is respiratory failure, asthma, pulmonary emphysema, children under two years of age.
An overdose of the drug can cause nervous tension, excessive excitability, a sense of anxiety and irritability, confusion, vomiting. If one or more symptoms occur, you should do a gastric lavage and stop taking the medicine.
Tos-May cough tablets: instructions for use
Dosage and administration are calculated based on the age of the patient. So, in the age category of twelve years or older, as well as adults, the drug is prescribed to take 1-2 tablets with a frequency of 4-6 times a day. The daily dose should not exceed sixteen tablets.
For children aged 6 to 12 years, the medicine is prescribed one tablet four times a day, the maximum dose is eight tablets. In children from 2 to 6 years, it is shown to take ½ tablets four times a day. The daily dose should not exceed four tablets "Tos-May."
Pills instruction advises not to swallow, but dissolve under the tongue. Thus, the medicine will be better absorbed by the body, and the effect will be achieved faster.
Undesirable consequences
Despite the effectiveness of the medication, side effects are sometimes observed after consuming Tos-May. Tablets (the instruction notes that it is necessary to consult a doctor before use) can cause drowsiness, nausea and pain in the abdomen, sleep disturbance. In some cases, patients suffered from diarrhea, flatulence and constipation. All these ailments disappeared immediately after the withdrawal of the drug.
special instructions
You should not take the drug at the same time as antidepressants (monoamine oxidase inhibitors), for example, with Nialamide or Pyrazidol, the drug Tos-May.
Instructions for use (reviews of the drug say that it is able to remove a cough in two days), advises not to exceed the indicated doses. If side effects occur, tablets should be discontinued. It is impossible to combine the use of the drug with the use of alcohol, and it should not be used for chronic cough during a period of bronchial asthma and pulmonary emphysema.
During pregnancy and lactation, before using tablets, consult your doctor. There is a possibility that during the treatment you will need to abandon breastfeeding. With extreme caution, the medicine is prescribed for liver diseases.
During treatment, some patients noted drowsiness, decreased reaction. The last symptom should be considered when driving a car and work associated with a special concentration of attention.
He talks about what should be stored in a dry and cool place, away from sunlight and be inaccessible to children, the drug "Tos-May" (tablets), instructions for use.
Cough Tablet Analogs
Drug substitutes are selected by the ATC code (R05FB02) and the active components that make up the drug. The main active substance in Tos-May is dextromethorphan hydrobromide. There were no analogues similar to the active substance, and the following medications are presented by the ATC code:
- Ambrobene.
- "Ambroxol 15".
- "Ambronol".
- "Ambrosan."
- Ambrospray.
- "Pectolvan Stop."
- Stoptussin.
This is just a small list of drugs that have a similar effect, in fact there are much more. The decision to replace one medicine with another should only be made by the therapist. Self-medication in this case will not give positive results, but will only exacerbate the situation, complicate the course of the disease and delay recovery.
The drug "Tos-May" - a reliable assistant in the fight against cough. It effectively and quickly eliminates the disease and does not cause side effects. Prevents the development of the disease.