In the article, we consider the instructions for use for the Enterofuril suspension.
This is a medicine from the broad-spectrum antimicrobial category. The medicine does not have systemic properties and is prescribed for the treatment of infectious diarrhea. The main active element is nifuroxazide, which is a derivative of 5-nitrofuran.
Suspension composition
This medication in the form of a suspension is a thick liquid that has a banana smell and yellow color. The main active element of this agent is nifuroxazide, and additional compounds are carbomer, sodium hydroxide, ethanol, methyl hydroxyparabenzoate, banana flavor, citric acid, water and sucrose.
Enterofuril suspension is contained in dark glass bottles with a volume of 90 ml. Cardboard packaging contains one bottle, a measuring spoon and an annotation with the rules of use.
Pharmacological features
Suspension "Enterofuril" is able to have a bacteriostatic and bactericidal effect, is active against various pathogens of digestive tract infections. The antimicrobial efficacy of this pharmacological drug is dose-dependent, while medium and low dosages have a bacteriostatic effect, and high doses have a bactericidal effect.
The bacteriostatic effect of Enterofuril medication is due to the inhibition of the dehydrogenase functionality, when the biosynthesis of the necessary compounds in the cells of pathogenic microorganisms is impaired. As a result, the main respiratory chain is blocked , the cyclicality of tricarboxylic acids changes, and the pathological cell loses its ability to reproduce.
The bactericidal effect of Enterofuril is due to the ability of high doses of the drug to destroy bacterial cell membranes. Due to such a violation of the integrity of the membrane, the destruction of bacteria occurs. In addition, this drug is able to inhibit the production of exotoxins by pathogen bacteria, resulting in reduced irritation of the intestinal epithelium and fluid production in the lumens of the digestive organs.
By increasing the phagocytic activity, the medication activates the immune system. It does not inhibit non-pathogenic flora, and therefore, with its use, there are no symptoms of dysbiosis. After oral administration of the suspension, Enterofuril is not absorbed in the digestive tract, and there are no systemic effects. The highest concentration of the drug is created in the intestine, after which the substances are excreted in the feces.
In addition to high efficiency in bacterial digestive infections, this pharmacological drug reduces the risk of superinfection in cases of the development of viral diarrhea, therefore, with such a pathology, the use of Enterofuril is very advisable.
Indications for use
According to the instructions for Enterofuril suspension, the main indications for the prescription of this drug are:
- Diarrhea of a bacterial nature of occurrence, in acute and chronic form (in the presence of helminth infestation, this medication is not used).
- Diarrhea in chronic colitis.
- Iatrogenic diarrhea, which is provoked by the use of antimicrobial drugs.
- According to indications, the use of Enterofuril suspension is advisable for diarrhea of unknown etiology.
List of contraindications
This pharmaceutical preparation is contraindicated for use with high sensitivity to nifuroxazide or other nitrofuran derivatives, as well as for the treatment of diseases in children under the age of 1 month. In addition, this medicine is not used to treat diarrhea in premature babies.
Method of application, dosage
In the treatment of diarrhea of various etiologies in patients older than 7 years of age, the medication can be used in capsule form. Up to 7 years old, it is recommended to use Enterofuril suspension. The duration of the treatment course, as well as the dosage in a particular clinical case, is determined by the doctor. The dosage of the medicine for adult patients is 200 mg (which is placed in one scoop) four times a day. The maximum dosage per day is 800 mg. The recommended course of therapy is 7 days.
How to apply Enterofuril suspension for children?
- At the age of 2-7 years, the dosage is 200 mg three times a day. The maximum dosage per day is 600 mg. The duration of treatment is no more than a week.
- Patients from 7 months to 2 years of age are prescribed 100 mg (half a scoop) three times a day. The daily dosage is 400 mg.
- Children 1-7 months old are prescribed 100 mg twice a day.
Enterofuril can be used regardless of the meal regimen. Shake the suspension well before use.
Side effects
This pharmaceutical product is generally well tolerated. In isolated cases, the occurrence of allergic reactions in the form of urticaria and rashes on the skin was observed.
This is confirmed by the instructions for use for Enterofuril suspension for children and adults.
Pregnancy
According to clinical indications, this medication can be prescribed during pregnancy, but only in situations where the benefits to the mother's body outweigh the threat to the fetus.
The active elements of Enterofuril are not able to penetrate into breast milk, therefore, this medication can be prescribed during the lactation process.
Drug interaction
Due to the lack of absorption, the interaction of Enterofuril with other medicines is unlikely. However, it is not recommended to take this medication with drugs containing ethyl alcohol. You can also not use "Enterofuril" in concomitant therapy with enterosorbents, in which case its effectiveness is significantly reduced.
Overdose symptoms
There is no evidence of signs of an overdose with Enterofuril. If you accidentally take high dosages of the drug, non-specific treatment is recommended: enterosorbents, oral, gastric lavage.
Special recommendations
Before using Enterofuril, it is important that you read the annotation carefully. There are some features of the correct administration of the drug in the form of a suspension, the list of which includes:
- During the treatment of severe diarrhea in children, it is important to carry out recovery measures aimed at the flow of fluid and mineral salts into the body.
- During the use of the drug, it is strictly forbidden to take alcoholic beverages.
- Before prescribing a medication, children who are breast-feeding should make sure that there is no insufficiency of the digestive enzymes that are responsible for the breakdown of carbohydrates.
- The main component does not affect the function of the cerebral cortex, the speed of psychomotor reactions and concentration.
This is stated in the instructions for use for Enterofuril suspension. With diarrhea, analogues may be used.
Analogs
The following drugs are similar in therapeutic effect to the medication:
- "Ecofuril" is an antimicrobial agent that is a derivative of nitrofuran. It blocks the functionality of dehydrogenases and respiratory chains, tricarboxylic acid cycles and other biochemical reactions in microbial cells and does not upset the balance of intestinal microflora. With diarrhea of bacterial origin, intestinal eubiosis is restored. When infected with enterotropic viruses, it blocks the development of bacterial superinfection. This medication is prescribed for diarrhea of various origins.
- "Nifuroxazide" is a similar medication with a similar therapeutic effect on the body. I prescribe it for acute and chronic diarrhea, in adults and children after 2 months, as well as for diarrhea, autoimmune gastritis, appendicitis and food intoxication.
- Stopdiar is an antimicrobial pharmacological agent, an absolute analogue of the Enterofuril medication. It has an identical pharmacological effect, indications and restrictions on admission.
Reviews
Given the information contained in the reviews for the medication in question, it is considered one of the most commonly prescribed medication for the treatment of diarrhea of various genesis. Most often it is used in the treatment of this condition in childhood, since the medicine has a pleasant smell and taste, which is very popular with children. Regarding the effectiveness of this medication, the reviews reflect the opinion of many patients who took it, and noted that this remedy helps very quickly and stops diarrhea for several hours.
Side effects from the use of this suspension, none of the people who lagged reviews, not observed. All of them note that the medication is very well tolerated and does not cause dyspeptic disorders.
Experts also left a lot of positive reviews about this medicine. They claim that “Enterofuril” at the moment can be considered one of the most popular and safe medicines on the pharmaceutical market, which has virtually no contraindications and does not provoke adverse reactions.
We reviewed the instructions for Enterofuril suspension for children and adults.