"Fluconazole" is a pharmacological group of drugs that relates to antifungal drugs. What is Fluconazole-Teva used for? The medication is used to eliminate various fungal infections that are sensitive to the active component of the drug by pathogens.
What components does the drug contain?
The drug is available in the form of capsules for oral use. The main active ingredient is fluconazole, its concentration in one capsule is one hundred and fifty milligrams. The structure of the medication also includes additional substances, which include:
- Silica.
- Salt of magnesium and stearic acid.
- Starch.
- Sodium salt of lauryl sulfuric acid.
- Carbohydrate disaccharide group.
There is only one capsule in the package, which is placed in the blister.
Pharmacological actions
According to the instructions for use, "Fluconazole" 150 mg has increased activity in inhibiting the growth of fungal bacteria. The action of the drug is to block the activity of enzymes.
After using the capsule, the orally active component is well and instantly absorbed into the general bloodstream. The active substance evenly spreads throughout the tissues, perfectly accumulates in the stratum corneum of the epidermis and its appendages, exchanges in the liver with the formation of inactive decay products, which are excreted mainly with urine.
"Fluconazole-Teva": indications
For the use of the drug, there are a number of specific indications that include fungal infections, for example:
- Cryptococcal meningitis is a fungal infection of the membranes and brain matter in people with weakened immune systems.
- Localized candidiasis.
- Dermatomycosis is a fungal skin disease caused by a certain pathogenic microflora.
- Pityriasis versicolor is a fungal infection of the superficial stratum corneum of a person.
- Onychomycosis is a disease that is localized in the area of the nail plate.
- Deep endemic mycoses.
The medication is also used as a preventive measure to prevent the occurrence of a fungal infection in people with normal or impaired body defenses.
What prohibitions does the drug have?
According to the instructions for use, "Fluconazole" 150 mg has certain prohibitions on the use of:
- Joint use with "Terfenadine", "Astemizole", as well as other drugs that lead to an extended ECG interval.
- Children's age up to four years.
- Individual intolerance to the active component.
With extreme caution, the medicine is used for diseases of the kidneys and liver, as well as the appearance of rashes on the skin in patients with fungal infections. Also, with caution, the drug is used by pregnant women.
How to take the drug?
Capsules are intended for oral use. They are not chewed, washed down with water. The dosage of the drug depends on the medical condition:
- With cryptococcal meningitis in adult patients and adolescents over fifteen years of age - on the first day the medication is prescribed at a dose of four hundred milligrams per day, then they switch to a maintenance dosage of two hundred mg per day.
- To prevent exacerbation of cryptococcal meningitis in people with severe immunodeficiency - after completing the course of primary treatment, which is aimed at the maximum elimination of the source of the disease. The medication is prescribed in a daily dosage of two hundred milligrams.
- With generalized candidiasis - on the first day four hundred milligrams per day are prescribed, then they switch to two hundred milligrams per day. In the absence of a sufficient pharmacological effect, they again switch to a dosage of four hundred milligrams.
- Candidiasis, which is localized on the mucous membrane of the oral cavity, esophagus - one hundred fifty milligrams once a day, the duration of the course varies from fourteen to twenty eight days.
- With vaginal candidiasis in women, it is necessary to take one hundred and fifty milligrams once, for prophylactic purposes, to prevent exacerbation after one month, the drug should be repeated.
- For preventive purposes to eliminate candidiasis of various localization - the dosage is set by a medical specialist individually, it can vary from fifty to four hundred milligrams per day.
- With pityriasis versicolor - three hundred milligrams per day once a week for three weeks, such a scheme can be adjusted by the attending doctor if necessary.
- With dermatomycosis, including diseases of the skin of the feet, one hundred and fifty milligrams once a week for four weeks.
- With onychomycosis, one hundred fifty mg is taken once a week, treatment continues until the nail plate is completely restored.
- With deep endemic mycoses - the dosage of the drug varies from two hundred to four hundred milligrams per day, the duration of therapy can reach two months.
According to reviews of Fluconazole-Teva, it is known that the capsule regimen for children has some similarities with adult dosing.
The main condition is the avoidance of high concentrations of the active substance (400 mg) per day. As a rule, the regimen and dosage are established individually by a medical specialist.
Fluconazole 50 mg
According to the instructions for use, it is known that this drug has exactly such indications.
For adults with cryptococcal meningitis, as a rule, four hundred milligrams are prescribed, and then therapy is continued at a dosage of two hundred to four hundred milligrams once a day.
According to the instructions for use with Fluconazole 50 mg, the drug can be used to prevent the recurrence of a dangerous brain disease of an infectious nature in patients with acquired immunodeficiency syndrome.
The duration of therapy depends on clinical efficacy, which is confirmed by mycological research. With cryptococcal meningitis, the duration of treatment is approximately six to eight weeks.
After completing the full treatment of the primary treatment, the drug is prescribed in a dosage of two hundred milligrams per day for a long time. What is the difference between "Fluconazole" and "Fluconazole-Teva"? In the second drug, the dosage is higher than in the first, so when treating a disease it is best suited. You do not need to take many capsules without irritating the mucous cavity of the gastrointestinal tract.
Adverse reactions
When using "Fluconazole-Teva" may occur negative phenomena from various organs and systems:
- Loss of appetite.
- Bloating.
- Migraine.
- Decreased platelet count.
- Leukopenia
- Agranulocytosis.
- Neutropenia
Very rarely, after the start of the course of therapy, hair can fall out, as well as cholesterol and triglycerides increase, the potassium content in the blood decreases, and the functioning of the kidneys is impaired. The appearance of negative pathological symptoms is considered the basis for discontinuation of treatment.
Overdose
According to reviews of Fluconazole-Teva, hallucinations and paranoid behavior may appear when the recommended pharmacological dosage of the capsules is significantly exceeded. In this situation, washing of the stomach and intestines is carried out, enterosorbents are prescribed.
Analogues of "Fluconazole"
Drugs that are similar in composition and pharmacological action are:
- "Mikosist".
- Diflucan.
- Flucostat.
Shelf life of "Fluconazole" is twenty-four months. The drug must be kept in a dark, dry, inaccessible place for children at an air temperature of plus fifteen to twenty degrees of heat. The cost of the drug varies from 150 to 230 rubles.
Opinions
Judging by the available reviews of Fluconazole-Teva, the drug of the Israeli pharmaceutical company is considered a highly effective antifungal drug. The medication allows you to instantly cope with a fungal infection.
Very often, women write positive feedback about the drug from thrush. It is noted that the drug not only eliminates the disease, but also prevent the recurrence of the disease.
Patients, leaving comments on "Fluconazole-Teva", say that the medicine helps instantly, it effectively eliminates the symptoms of fungal diseases.
People mention that capsules are relatively inexpensive, but at the same time help completely get rid of nail fungus and other unpleasant diseases.